Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Carolyn K Suzuki"'
Autor:
Eman Rashed, Paulo Lizano, Huacheng Dai, Andrew Thomas, Carolyn K Suzuki, Christophe Depre, Hongyu Qiu
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119537 (2015)
Stress-inducible heat shock protein 22 (Hsp22) confers protection against ischemia through induction of the inducible isoform of nitric oxide synthase (iNOS). Hsp22 overexpression in vivo stimulates cardiac mitochondrial respiration, whereas Hsp22 de
Externí odkaz:
https://doaj.org/article/6328ef46f74b46dd9325c8c0c7908df2
Autor:
Yujie Li, Dawei Huang, Lianqun Jia, Fugen Shangguan, Shiwei Gong, Linhua Lan, Zhiyin Song, Juan Xu, Chaojun Yan, Tongke Chen, Yin Tan, Yongzhang Liu, Xingxu Huang, Carolyn K. Suzuki, Zhongzhou Yang, Guanlin Yang, Bin Lu
Publikováno v:
Research, Vol 6 (2023)
Interorganelle contacts and communications are increasingly recognized to play a vital role in cellular function and homeostasis. In particular, the mitochondria–endoplasmic reticulum (ER) membrane contact site (MAM) is known to regulate ion and li
Externí odkaz:
https://doaj.org/article/685beb4752a3456b9a45618c253a4478
Publikováno v:
MedEdPORTAL, Vol 16 (2020)
Introduction As evidenced by student performance on various assessments, pharmacotherapy remains a comparative weakness in undergraduate medical education, with several institutions developing novel strategies for students to apply these principles i
Externí odkaz:
https://doaj.org/article/3d7c98895bd14ea39622bc50b57fceca
Autor:
Tong Liu, Michinari Nakamura, Mingming Tong, Junichi Sadoshima, Lin Yan, Toshihide Kashihara, Carolyn K. Suzuki, Diego Fraidenraich, Erdene Baljinnyam, Sundararajan Venkatesh, Lai-Hua Xie, Hong Li, Shin Ichi Oka
Publikováno v:
Am J Physiol Regul Integr Comp Physiol
Mitochondria play key roles in the differentiation and maturation of human cardiomyocytes (CMs). As human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) hold potential in the treatment of heart diseases, we sought to identify key mi
Autor:
Yujie Li, Dawei Huang, Fugen Shangguan, Lianqun Jia, Linhua Lan, Shiwei Gong, Yingchao Shi, Zhiying Song, Juan Xu, Chaojun Yan, Tongke Chen, Mingjie Xu, Xingxu Huang, Carolyn K. Suzuki, Zhongzhou Yang, Guanlin Yang, Bin Lu
Protein quality control is pivotal to cellular homeostasis and integrity of cardiomyocytes for maintenance of normal heart function. The unfolded protein response (UPR) is an adaptive process to modulate protein quality control in the endoplasmic ret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aaba5bd0cb4231c155be19d67222d64f
https://doi.org/10.21203/rs.3.rs-1136819/v1
https://doi.org/10.21203/rs.3.rs-1136819/v1
Autor:
Jae Lee, Ashutosh K. Pandey, Sundararajan Venkatesh, Jayapalraja Thilagavathi, Tadashi Honda, Kamal Singh, Carolyn K. Suzuki
Publikováno v:
The Journal of biological chemistry. 298(3)
The mitochondrial protein LonP1 is an ATP-dependent protease that mitigates cell stress and calibrates mitochondrial metabolism and energetics. Biallelic mutations in the LONP1 gene are known to cause a broad spectrum of diseases, and LonP1 dysregula
Autor:
Shuijie Li, Wenyu Li, Juan Yuan, Petra Bullova, Jieyu Wu, Xuepei Zhang, Yong Liu, Monika Plescher, Javier Rodriguez, Oscar C. Bedoya-Reina, Paulo R. Jannig, Paula Valente-Silva, Meng Yu, Marie Arsenian Henriksson, Roman A. Zubarev, Anna Smed-Sörensen, Carolyn K. Suzuki, Jorge L. Ruas, Johan Holmberg, Catharina Larsson, C. Christofer Juhlin, Alex von Kriegsheim, Yihai Cao, Susanne Schlisio
Publikováno v:
Nature Metabolism. 4:1421-1421
Autor:
Min Li, Satvik Mareedu, Carlos López-Otín, Ghassan Yehia, Sundararajan Venkatesh, Toshiro Saito, Peiyong Zhai, Mingming Tong, Clea Bárcena, Carolyn K. Suzuki, Junichi Sadoshima, Eman Rashed
Publikováno v:
Journal of Molecular and Cellular Cardiology
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Rationale LonP1 is an essential mitochondrial protease, which is crucial for maintaining mitochondrial proteostasis and mitigating cell stress. However, the importance of LonP1 during cardiac stress is largely unknown. Objective To determine the func
Autor:
Shuijie Li, Wenyu Li, Juan Yuan, Petra Bullova, Jieyu Wu, Xuepei Zhang, Yong Liu, Monika Plescher, Javier Rodriguez, Oscar C. Bedoya-Reina, Paulo R. Jannig, Paula Valente-Silva, Meng Yu, Marie Arsenian Henriksson, Roman A. Zubarev, Anna Smed-Sörensen, Carolyn K. Suzuki, Jorge L. Ruas, Johan Holmberg, Catharina Larsson, C. Christofer Juhlin, Alex von Kriegsheim, Yihai Cao, Susanne Schlisio
Publikováno v:
Li, S, Liu, W, Yuan, J, Bullova, P, Wu, J, Zhang, X, Yong, L, Plescher, M, Rodriguez, J, Bedoya Reina, O, Jannig, P R, Valente-Silva, P, Yu, M, Arsenian-Henriksson, M, Zubarev, R A, Smed-Sörensen, A, Suzuki, C K, Ruas, J L, Holmberg, J, Larsson, C, Juhlin, C C, von Kriegsheim, A, Cao, Y & Schlisio, S 2022, ' Impaired oxygen-sensitive regulation of mitochondrial biogenesis within the von Hippel-Lindau syndrome ', Nature Metabolism . https://doi.org/10.1038/s42255-022-00593-x
Mitochondria are the main consumers of oxygen within the cell. How mitochondria sense oxygen levels remains unknown. Here we show an oxygen-sensitive regulation of TFAM, an activator of mitochondrial transcription and replication, whose alteration is
Publikováno v:
MedEdPORTAL : the Journal of Teaching and Learning Resources
MedEdPORTAL, Vol 16 (2020)
MedEdPORTAL, Vol 16 (2020)
Introduction As evidenced by student performance on various assessments, pharmacotherapy remains a comparative weakness in undergraduate medical education, with several institutions developing novel strategies for students to apply these principles i