Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Carolyn J Padoa"'
Publikováno v:
BMC Endocrine Disorders, Vol 22, Iss 1, Pp 1-8 (2022)
Abstract Background Vitamin D deficiency and the vitamin D pathway have previously been associated with type 1 diabetes (T1D). The majority of vitamin D is transported through the blood bound to the vitamin D binding protein (VDBP). Two polymorphisms
Externí odkaz:
https://doaj.org/article/125692aebbbd402a8bdd477a77f93023
Publikováno v:
BMC Endocrine Disorders, Vol 21, Iss 1, Pp 1-8 (2021)
Abstract Background Autoantibodies to β-cell specific antigens are markers of type 1 diabetes. The most recently identified autoantibodies are targeted to the zinc transporter 8 (ZnT8) protein located in the membrane of β-cell insulin secretory gra
Externí odkaz:
https://doaj.org/article/aa701a4f223547f98e14be673245489a
Publikováno v:
Southern African Journal of HIV Medicine, Vol 21, Iss 1, Pp e1-e15 (2020)
Background: The measurement of serum creatinine is a standard requirement of the medical management of people living with HIV. Renal dysfunction is common, both as a complication of HIV-infection and as a result of its treatment. The detection of abn
Externí odkaz:
https://doaj.org/article/82dd87db9e964421b5c17e8103d1b1e7
Publikováno v:
Kidney & Blood Pressure Research, Vol 45, Iss 6, Pp 1009-1017 (2020)
Introduction: The C allele of the ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP-1) rs1044498 polymorphism has previously been associated with increased binding of ENPP-1 to the insulin receptor (IR), resulting in decreased IR signalling an
Publikováno v:
BMC endocrine disorders. 22(1)
Background Vitamin D deficiency and the vitamin D pathway have previously been associated with type 1 diabetes (T1D). The majority of vitamin D is transported through the blood bound to the vitamin D binding protein (VDBP). Two polymorphisms in the V
Publikováno v:
BMC Endocrine Disorders
BMC Endocrine Disorders, Vol 21, Iss 1, Pp 1-8 (2021)
BMC Endocrine Disorders, Vol 21, Iss 1, Pp 1-8 (2021)
Background Autoantibodies to β-cell specific antigens are markers of type 1 diabetes. The most recently identified autoantibodies are targeted to the zinc transporter 8 (ZnT8) protein located in the membrane of β-cell insulin secretory granules. Th
Autor:
J. Paul Banga, Laszlo Hegedüs, Jacqueline A. Gilbert, Daniel El Fassi, Carolyn J. Padoa, Claus Henrik Nielsen
Publikováno v:
El Fassi, D, Banga, J P, Gilbert, J A, Padoa, C, Hegedüs, L & Nielsen, C H 2008, ' Treatment of Graves' disease with rituximab specifically reduces the production of thyroid stimulating autoantibodies ', Clinical Immunology, vol. 130, no. 3, pp. 252-258 . https://doi.org/10.1016/j.clim.2008.09.007
Udgivelsesdato: 2008-Oct-27 Treatment of Graves' disease (GD) with the B-lymphocyte depleting agent rituximab in addition to standard methimazole-therapy prolongs remission. Paradoxically, it does not mediate a reduction in thyrotropin receptor antib
Autor:
Nigel J. Crowther, Carolyn J. Padoa
Publikováno v:
Diabetes Research and Clinical Practice. 74:S51-S62
A revolution has occurred in the field of antibody engineering since Kohler and Milstein described a technique for the production of monoclonal antibodies in 1975. Their paper paved the way for future discoveries which have culminated in the use of r
Autor:
E Ortqvist, Mona Landin-Olsson, Carolyn J. Padoa, James W. Thomas, Carina Törn, T. R. Hall, Christiane S. Hampe
Publikováno v:
Clinical and Experimental Immunology. 146:9-14
Summary Autoantibodies to insulin (IAA) are one of the first markers of the autoimmune process leading to type 1 diabetes (T1D). While other autoantibodies in T1D have been studied extensively, relatively little is known about IAA and their binding s
Autor:
J. Paul Banga, Jefferson Foote, Carolyn J. Padoa, Christiane S. Hampe, Eva Örtqvist, T. R. Hall, Marinos C. Dalakas, Raghavanpillai Raju
Publikováno v:
The Journal of Immunology. 175:7755-7762
Autoantibodies to the 65-kDa isoform of glutamate decarboxylase GAD65 (GAD65Ab) are strong candidates for a pathological role in Stiff-Person syndrome (SPS). We have analyzed the binding specificity of the GAD65Ab in serum and cerebrospinal fluid (CS