Zobrazeno 1 - 10 of 15 pro vyhledávání: '"Carolyn G. J. Moonen"'
1
Akademický článek
TREM2 Promotes Immune Evasion by Mycobacterium tuberculosis in Human Macrophages
Autor: Ankita Dabla, Yi Chu Liang, Nusrah Rajabalee, Courtney Irwin, Carolyn G. J. Moonen, Jessie V. Willis, Stefania Berton, Jim Sun
Publikováno v: mBio, Vol 13, Iss 4 (2022)
ABSTRACT Macrophage surface receptors are critical for pathogen defense, as they are the gatekeepers for pathogen entry and sensing, which trigger robust immune responses. TREM2 (triggering receptor expressed on myeloid cells 2) is a transmembrane su
Externí odkaz: https://doaj.org/article/3fbff13b69614e4ea3be03628ae8cd32
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2
Akademický článek
Chronic Exposure of Gingival Fibroblasts to TLR2 or TLR4 Agonist Inhibits Osteoclastogenesis but Does Not Affect Osteogenesis
Autor: Gerasimos D. Karlis, Emily Schöningh, Ineke D. C. Jansen, Ton Schoenmaker, Jolanda M. A. Hogervorst, Henk A. van Veen, Carolyn G. J. Moonen, Katarzyna B. Łagosz-Ćwik, Tim Forouzanfar, Teun J. de Vries
Publikováno v: Frontiers in Immunology, Vol 11 (2020)
Chronic exposure to periodontopathogenic bacteria such as Porphyromonas gingivalis and the products of these bacteria that interact with the cells of the tooth surrounding tissues can ultimately result in periodontitis. This is a disease that is char
Externí odkaz: https://doaj.org/article/7fd462e788424f469fa633b27601df2b
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3
Akademický článek
The Challenge of Teaching Essential Immunology Laboratory Skills to Undergraduates in One Month—Experience of an Osteoimmunology Course on TLR Activation
Autor: Teun J. de Vries, Ton Schoenmaker, Henk A. van Veen, Jolanda Hogervorst, Przemek M. Krawczyk, Carolyn G. J. Moonen, Ineke D. C. Jansen
Publikováno v: Frontiers in Immunology, Vol 10 (2019)
Acquiring immunology laboratory skills during undergraduate studies is often a prerequisite for admission to Masters’ programs. Many broad liberal arts and sciences honors degree colleges struggle in teaching these essentials since only limited tim
Externí odkaz: https://doaj.org/article/2c59bf22cb70408586a41bdaedc480d4
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4
Akademický článek
Oral Neutrophils Characterized: Chemotactic, Phagocytic, and Neutrophil Extracellular Trap (NET) Formation Properties
Autor: Carolyn G. J. Moonen, Josefine Hirschfeld, Lili Cheng, Iain L. C. Chapple, Bruno G. Loos, Elena A. Nicu
Publikováno v: Frontiers in Immunology, Vol 10 (2019)
Maintenance of oral health is in part managed by the immune-surveillance and antimicrobial functions of polymorphonuclear leukocytes (PMNs), which migrate from the circulatory system through the oral mucosal tissues as oral PMNs (oPMNs). In any micro
Externí odkaz: https://doaj.org/article/1b636b7396824ae09d7578c49709b62e
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5
Akademický článek
The Possible Role of Neutrophils in the Induction of Osteoclastogenesis
Autor: Carolyn G. J. Moonen, Teun J. de Vries, Patrick Rijkschroeff, Patrice E. Poubelle, Elena A. Nicu, Bruno G. Loos
Publikováno v: Journal of Immunology Research, Vol 2019 (2019)
The ligand of the receptor activator of NF-κB (RANKL) is a key molecule in the formation of osteoclasts, the key cells that cause the disease-associated alveolar bone resorption in periodontitis. We hypothesized that polymorphonuclear leukocytes (PM
Externí odkaz: https://doaj.org/article/e0784bcbcb0f433184ca58077adea348
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6
Akademický článek
Survival, Retention, and Selective Proliferation of Lymphocytes Is Mediated by Gingival Fibroblasts
Autor: Carolyn G. J. Moonen, Sven T. Alders, Hetty J. Bontkes, Ton Schoenmaker, Elena A. Nicu, Bruno G. Loos, Teun J. de Vries
Publikováno v: Frontiers in Immunology, Vol 9 (2018)
Periodontitis, a chronic inflammatory disease of the periodontium, is characterized by osteoclast-mediated alveolar bone destruction. Gingival fibroblasts (GFs) present in the bone-lining mucosa have the capacity to activate the formation of osteocla
Externí odkaz: https://doaj.org/article/17885d6ba1db4f25a31a0355f90b725a
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8
Characterization, Quantification, and Visualization of Neutrophil Extracellular Traps
Autor: Josefine, Hirschfeld, Ilaria J, Chicca, Carolyn G J, Moonen, Phillipa C, White, Martin R, Ling, Helen J, Wright, Paul R, Cooper, Mike R, Milward, Iain L C, Chapple
Publikováno v: Methods in molecular biology (Clifton, N.J.). 2588
Following the discovery of neutrophil extracellular traps (NETs) in 2004 by Brinkmann and colleagues, there has been extensive research into the role of NETs in a number of inflammatory diseases, including periodontitis. This chapter describes the cu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9cbba1b65e252eed5410a60859b8c25c
https://pubmed.ncbi.nlm.nih.gov/36622545
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9
Periodontal therapy increases neutrophil extracellular trap degradation
Autor: Sergio Bizzarro, Carolyn G. J. Moonen, Kirsten Gd Buurma, Elena A. Nicu, Mouri Rj Faruque, Bruno G. Loos, Erol Liefferink, Maria G. Balta
Publikováno v: Innate Immunity, Vol 26 (2020)
Innate Immunity
In periodontitis, polymorphonuclear leucocytes (PMNs) are activated. They entrap and eliminate pathogens by releasing neutrophil extracellular traps (NETs). Abnormal NET degradation is part of a pro-inflammatory status, affecting co-morbidities such
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae46ab5d1b3ad7af59780ca72c714496
https://doi.org/10.1177/1753425919889392
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10
Chronic exposure of gingival fibroblasts to TLR2 or TLR4 agonist inhibits osteoclastogenesis but does not affect osteogenesis
Autor: Emily Schöningh, Gerasimos D. Karlis, Teun J. de Vries, Jolanda M. A. Hogervorst, Carolyn G. J. Moonen, Ton Schoenmaker, Ineke D. C. Jansen, Tim Forouzanfar, Henk A. van Veen, Katarzyna B. Łagosz-Ćwik
Publikováno v: Karlis, G D, Schöningh, E, Jansen, I D C, Schoenmaker, T, Hogervorst, J M A, van Veen, H A, Moonen, C G J, Łagosz-Ćwik, K B, Forouzanfar, T & de Vries, T J 2020, ' Chronic exposure of gingival fibroblasts to TLR2 or TLR4 agonist inhibits osteoclastogenesis but does not affect osteogenesis ', Frontiers in Immunology, vol. 11, 1693 . https://doi.org/10.3389/fimmu.2020.01693
Frontiers in Immunology, 11:1693. Frontiers Media S.A.
Karlis, G D, Schöningh, E, Jansen, I D C, Schoenmaker, T, Hogervorst, J M A, van Veen, H A, Moonen, C G J, Łagosz-Ćwik, K B, Forouzanfar, T & de Vries, T J 2020, ' Chronic Exposure of Gingival Fibroblasts to TLR2 or TLR4 Agonist Inhibits Osteoclastogenesis but Does Not Affect Osteogenesis ', Frontiers in Immunology, vol. 11, 1693 . https://doi.org/10.3389/fimmu.2020.01693
Frontiers in Immunology, Vol 11 (2020)
Frontiers in immunology, 11:1693. Frontiers Media S.A.
Frontiers in Immunology
Chronic exposure to periodontopathogenic bacteria such as Porphyromonas gingivalis and the products of these bacteria that interact with the cells of the tooth surrounding tissues can ultimately result in periodontitis. This is a disease that is char
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96856eaeb5a3c58ceeb61386d508d517
https://research.vu.nl/en/publications/4f4fa955-52b1-4b06-bd09-78a51de01e38
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