Výsledky vyhledávání - "Carolyn G Marsden"

Akademický článek

The Tumor-Associated Variant RAD51 G151D Induces a Hyper-Recombination Phenotype.

Autor: Carolyn G Marsden, Ryan B Jensen, Jennifer Zagelbaum, Eli Rothenberg, Scott W Morrical, Susan S Wallace, Joann B Sweasy

Publikováno v: PLoS Genetics, Vol 12, Iss 8, p e1006208 (2016)

The RAD51 protein plays a key role in the homology-directed repair of DNA double-strand breaks and is important for maintaining genome stability. Here we report on a novel human RAD51 variant found in an aggressive and therapy-refractive breast carci

Externí odkaz: https://doaj.org/article/862a410adb6e4d8390160c03ec59b5dd

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Akademický článek

Disseminated breast cancer cells acquire a highly malignant and aggressive metastatic phenotype during metastatic latency in the bone.

Autor: Carolyn G Marsden, Mary Jo Wright, Latonya Carrier, Krzysztof Moroz, Brian G Rowan

Publikováno v: PLoS ONE, Vol 7, Iss 11, p e47587 (2012)

BACKGROUND: Disseminated tumor cells (DTCs) in the bone marrow may exist in a dormant state for extended periods of time, maintaining the ability to proliferate upon activation, engraft at new sites, and form detectable metastases. However, understan

Externí odkaz: https://doaj.org/article/065566f1bcd040589ce48c7ec8b3360d

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