Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Carolyn D. Jackson"'
Autor:
Daniel S. Greenspan, Kate Fisher, Sreemoti Banerjee, Catherine B. Lawrence, Carolyn D. Jackson, Katherine A. B. Kellett, Christopher J. Duff, Nobuyo Maeda, Nigel M. Hooper, Robert J. Andrew
Publikováno v:
Scientific Reports
Banerjee, S, Andrew, R J, Duff, C J, Fisher, K, Jackson, C D, Lawrence, C B, Maeda, N, Greenspan, D S, Kellett, K & Hooper, N 2019, ' Proteolysis of the low density lipoprotein receptor by bone morphogenetic protein-1 regulates cellular cholesterol uptake ', Scientific Reports . https://doi.org/10.1038/s41598-019-47814-0
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Banerjee, S, Andrew, R J, Duff, C J, Fisher, K, Jackson, C D, Lawrence, C B, Maeda, N, Greenspan, D S, Kellett, K & Hooper, N 2019, ' Proteolysis of the low density lipoprotein receptor by bone morphogenetic protein-1 regulates cellular cholesterol uptake ', Scientific Reports . https://doi.org/10.1038/s41598-019-47814-0
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
The development of cardiovascular disease is intimately linked to elevated levels of low-density lipoprotein (LDL) cholesterol in the blood. Hepatic LDL receptor (LDLR) levels regulate the amount of plasma LDL. We identified the secreted zinc metallo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ae9398889d0b645d0a6175f4006391d
https://pubmed.ncbi.nlm.nih.gov/32042031
https://pubmed.ncbi.nlm.nih.gov/32042031
Autor:
Herbert Baybutt, Isobel J. Whitehouse, Jean Manson, Debbie Brown, Pedro Piccardo, Anthony J. Turner, Carolyn D. Jackson, Heledd H. Griffiths, Nigel M. Hooper, Katherine A.B. Kellett
Publikováno v:
Griffiths, H H, Whitehouse, I J, Baybutt, H, Brown, D, Kellett, K A, Jackson, C D, Turner, A J, Piccardo, P, Manson, J C & Hooper, N M 2011, ' Prion protein interacts with bace1 and differentially regulates its activity towards wild type and swedish mutant amyloid precursor protein ', Journal of Biological Chemistry, vol. 286, no. 38, pp. 33489-33500 . https://doi.org/10.1074/jbc.M111.278556
In Alzheimer disease amyloid-β (Aβ) peptides derived from the amyloid precursor protein (APP) accumulate in the brain. Cleavage of APP by the β-secretase BACE1 is the rate-limiting step in the production of Aβ. We have reported previously that th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a495d596c0a192d64f5998d8bc4cfc7
https://doi.org/10.1074/jbc.m111.278556
https://doi.org/10.1074/jbc.m111.278556
Publikováno v:
Journal of Alzheimer's Disease. 22:1023-1031
The cellular form of the prion protein (PrPC) has been shown to inhibit the production of amyloid-β which is critically involved in the pathogenesis of Alzheimer's disease (AD). We examined the expression of PrPC by immunoblot analysis in the hippoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6ec8ebeb42998e9366749f6b90bcb3e
https://doi.org/10.3233/jad-2010-101071
https://doi.org/10.3233/jad-2010-101071
Publikováno v:
Journal of immunological methods. 429
Half-antibody fragments are a promising reagent for biosensing, drug-delivery and labeling applications, since exposure of the free thiol group in the Fc hinge region allows oriented reaction. Despite the structural variations among the molecules of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b801853d7ff1222d511b63c49585c52
https://pubmed.ncbi.nlm.nih.gov/26779832
https://pubmed.ncbi.nlm.nih.gov/26779832
Autor:
Rachel Dahan, Shoshana Keynan, Kay Barnes, Mogher Khamaisi, Anthony J. Turner, Itamar Raz, Carolyn D. Jackson
Publikováno v:
Journal of Vascular Research. 41:131-140
Endothelin-1 (ET-1) is both a potent vasoconstrictor and mitogenic factor that has been implicated as a cause of the micro- and macrovascular complications of diabetes mellitus. The pathway by which the high-glucose environment of diabetes mediates i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e2416c8f544d4dcc48b64bda56658c
https://doi.org/10.1159/000077132
https://doi.org/10.1159/000077132
Publikováno v:
Experimental biology and medicine (Maywood, N.J.). 231(6)
Endothelin-converting enzyme (ECE-1) is a critical enzyme in the production of the potent vasoconstrictor peptide endothelin (ET-1). It has previously been shown that the levels of both ET-1 and ECE-1 are raised in atherosclerosis, but the possible r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0027b439917ea615b2ab45f69507285a
https://pubmed.ncbi.nlm.nih.gov/16741001
https://pubmed.ncbi.nlm.nih.gov/16741001
Autor:
Carolyn D, Jackson, Anthony J, Turner
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 206
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d7f9ca88d90b0ba66aa4ef5d6a214e96
https://pubmed.ncbi.nlm.nih.gov/12152223
https://pubmed.ncbi.nlm.nih.gov/12152223