Zobrazeno 1 - 10 of 24 pro vyhledávání: '"Carolyn A. Sawyer"'
1
Successful Kinetic Impact into an Asteroid for Planetary Defense
Autor: R. Terik Daly, Carolyn M. Ernst, Olivier S. Barnouin, Nancy L. Chabot, Andrew S. Rivkin, Andrew F. Cheng, Elena Y. Adams, Harrison F. Agrusa, Elisabeth D. Abel, Amy L. Alford, Erik I. Asphaug, Justin A. Atchison, Andrew R. Badger, Paul Baki, Ronald-L. Ballouz, Dmitriy L. Bekker, Julie Bellerose, Shyam Bhaskaran, Bonnie J. Buratti, Saverio Cambioni, Michelle H. Chen, Steven R. Chesley, George Chiu, Gareth S. Collins, Matthew W. Cox, Mallory E. DeCoster, Peter S. Ericksen, Raymond C. Espiritu, Alan S. Faber, Tony L. Farnham, Fabio Ferrari, Zachary J. Fletcher, Robert W. Gaskell, Dawn M. Graninger, Musad A. Haque, Patricia A. Harrington-Duff, Sarah Hefter, Isabel Herreros, Masatoshi Hirabayashi, Philip M. Huang, Syau-Yun W. Hsieh, Seth A. Jacobson, Stephen N. Jenkins, Mark A. Jensenius, Jeremy W. John, Martin Jutzi, Tomas Kohout, Timothy O. Krueger, Frank E. Laipert, Norberto R. Lopez, Robert Luther, Alice Lucchetti, Declan M. Mages, Simone Marchi, Anna C. Martin, Maria E. McQuaide, Patrick Michel, Nicholas A. Moskovitz, Ian W. Murphy, Naomi Murdoch, Shantanu P. Naidu, Hari Nair, Michael C. Nolan, Jens Ormö, Maurizio Pajola, Eric E. Palmer, James M. Peachey, Petr Pravec, Sabina D. Raducan, K. T. Ramesh, Joshua R. Ramirez, Edward L. Reynolds, Joshua E. Richman, Colas Q. Robin, Luis M. Rodriguez, Lew M. Roufberg, Brian P. Rush, Carolyn A. Sawyer, Daniel J. Scheeres, Petr Scheirich, Stephen R. Schwartz, Matthew P. Shannon, Brett N. Shapiro, Caitlin E. Shearer, Evan J. Smith, R. Joshua Steele, Jordan K. Steckloff, Angela M. Stickle, Jessica M. Sunshine, Emil A. Superfin, Zahi B. Tarzi, Cristina A. Thomas, Justin R. Thomas, Josep M. Trigo-Rodríguez, B. Teresa Tropf, Andrew T. Vaughan, Dianna Velez, C. Dany Waller, Daniel S. Wilson, Kristin A. Wortman, Yun Zhang
Publikováno v: Nature
Nature, 2023, 616, pp.443-447. ⟨10.1038/s41586-023-05810-5⟩
While no known asteroid poses a threat to Earth for at least the next century, the catalog of near-Earth asteroids is incomplete for objects whose impacts would produce regional devastation. Several approaches have been proposed to potentially preven
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4f78e5a4ef0a89a92cae13658ec5011
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2
Feasibility of a Clinic-Community Partnership to Treat Childhood Obesity
Autor: Jessica Hoffman, Leah Frerichs, Kiah Gaskin, Sarah C. Armstrong, Carolyn M. Sawyer, Asheley Cockrell Skinner, Maria Andrews
Publikováno v: Clinical Pediatrics. 57:783-791
Background. “Bull City Fit” is a childhood obesity treatment partnership between Duke Children’s pediatric weight management clinic and Durham Department of Parks and Recreation. Objectives. Report on feasibility and implementation, characteris
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::685ff7075f07b682557fe08bc1640100
https://doi.org/10.1177/0009922817734359
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4
A Novel Healthcare-community Partnership for Childhood Obesity Treatment: Study Design and Baseline Findings
Autor: Kiah Gaskin, Maria Andrews, Sarah C. Armstrong, Jessica Lyden, Carolyn M. Sawyer, Leah Frerichs, Asheley Cockrell Skinner
Publikováno v: Innovations in Obesity Prevention, Assessment and Treatment Forum.
Significance Childhood obesity disproportionately impacts low-income and racial and ethnic minority communities, yet effective interventions accessible to these communities remain limited. Recommendations for treating childhood obesity encourage link
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9955bec3eaf967cc5d7cd003d721334b
https://doi.org/10.1542/peds.141.1_meetingabstract.224
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5
A tingling sanshool derivative excites primary sensory neurons and elicits nocifensive behavior in rats
Autor: Mirela Iodi Carstens, Margaret Ivanov, Jay Patrick Slack, Carolyn M. Sawyer, Stephan Furrer, Karen L. Zanotto, Susan Cheung, Amanda H. Klein, Earl Carstens, Christopher T. Simons
Publikováno v: Journal of Neurophysiology. 105:1701-1710
Szechuan peppers contain hydroxy-α-sanshool that imparts desirable tingling, cooling, and numbing sensations. Hydroxy-α-sanshool activates a subset of sensory dorsal root ganglion (DRG) neurons by inhibiting two-pore potassium channels. We presentl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0d81409041633f436edf89d91ace8fd
https://doi.org/10.1152/jn.00922.2010
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6
Activation of Lumbar Spinal Wide-Dynamic Range Neurons by a Sanshool Derivative
Autor: Carolyn M. Sawyer, Mirela Iodi Carstens, Christopher T. Simons, Jay Patrick Slack, T. Scott McCluskey, Earl Carstens, Stefan Michael Furrer
Publikováno v: Journal of Neurophysiology. 101:1742-1748
The enigmatic sensation of tingle involves the activation of primary sensory neurons by hydroxy-α-sanshool, a tingly agent in Szechuan peppers, by inhibiting two-pore potassium channels. Central mechanisms mediating tingle sensation are unknown. We
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e532280363d3f217c42218e617e0cf1
https://doi.org/10.1152/jn.91311.2008
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8
Capsaicin avoidance as a measure of chemical hyperalgesia in orofacial nerve injury models
Autor: Carolyn M. Sawyer, Yves Boucher, Earl Carstens, Austin W. Merrill, Mirela Iodi Carstens, Karen L. Zanotto
Publikováno v: Neuroscience letters. 543
Many patients suffer from trigeminal neuralgia and other types of orofacial pain that are poorly treated, necessitating preclininal animal models for development of mechanisms-based therapies. The present study assessed capsaicin avoidance and other
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d50001f6e7846798f9a7fbfbb8400799
https://pubmed.ncbi.nlm.nih.gov/23562513
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9
Topical hindpaw application of L-menthol decreases responsiveness to heat with biphasic effects on cold sensitivity of rat lumbar dorsal horn neurons
Autor: Mirela Iodi Carstens, Auva Davoodi, Margaret Ivanov, Kenichi Takechi, Amanda H. Klein, Earl Carstens, Carolyn M. Sawyer
Menthol is used in pharmaceutical applications because of its desired cooling and analgesic properties. The neural mechanism by which topical application of menthol decreases heat pain is not fully understood. We investigated the effects of topical m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44129849c174dab368daacd256036672
https://europepmc.org/articles/PMC3402706/
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10
Self- and cross-desensitization of oral irritation by menthol and cinnamaldehyde (CA) via peripheral interactions at trigeminal sensory neurons
Autor: Amanda H. Klein, Susan Cheung, Earl Carstens, Margaret Ivanov, Karen L. Zanotto, Mirela Iodi Carstens, Carolyn M. Sawyer
Publikováno v: Chemical senses. 36(2)
Menthol and cinnamaldehyde (CA) are plant-derived spices commonly used in oral hygiene products, chewing gum, and many other applications. However, little is known regarding their sensory interactions in the oral cavity. We used a human psychophysics
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::900bd8f8a556da1419aebf75a9fbfe3f
https://pubmed.ncbi.nlm.nih.gov/21059698
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