Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Carolyn A. Rahn"'
Autor:
CHIN K. LEE, BUDDY G. BROWN, BESTY A. REED, CAROLYN A. RAHN, CHRISTOPHER R. E. GOGGINS, DAVID J. DOOLITTLE, A. WALLACE HAYES
Publikováno v:
Toxicological Sciences. 19:141-146
Publikováno v:
Mutation Research/Genetic Toxicology. 260:9-18
Cigarette smokers have been reported to void urine which is more mutagenic than that voided by non-smokers, but the specific urinary mutagen(s) have not been identified. Since mechanistic studies are best performed in animal models, the objective of
Autor:
David J. Doolittle, Michael F. Borgerding, A. Wallace Hayes, J. Donald deBethizy, Johnnie R. Hayes, John Hughes Reynolds, Kevin T. McManus, Riley A. Davis, Gary T. Burger, Carolyn A. Rahn, John H. Robinson
Publikováno v:
The Journal of Clinical Pharmacology. 30:755-763
Cigarettes can be developed that heat rather than burn tobacco. Such products would be expected to have less "tar" and other combustion products than cigarettes that burn tobacco. With one product of this type, benzo(a)pyrene, N-nitrosamines, phenoli
Publikováno v:
Environmental and molecular mutagenesis. 17(4)
Cigarette smokers have been reported to void urine that is more mutagenic, as measured in the Salmonella/microsome assay, than urine voided by nonsmokers. Several previous studies have attempted to correlate indices of tobacco smoke exposure (e.g., n
Autor:
David J. Doolittle, Elliot S. Vesell, Carolyn A. Rahn, Gary T. Burger, George Howard, A.W. Hayes, G.T. Passananti, E. Riccio
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 28(9)
Measuring the mutagenicity of urine is widely viewed as a means of evaluating human exposure to potentially genotoxic materials. Diet and cigarette smoking have both been reported to affect the mutagenicity of human urine, but the relationship betwee
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 888:1-9
Because the intestine is the first pass organ for orally administered drugs and because some of these drugs are known to undergo oxidative metabolism leading to the formation of free radicals, we investigated the potential for this to occur in cell s
Effect of cooking methods on the mutagenicity of food and on urinary mutagenicity of human consumers
Autor:
B. A. Reed, G.T. Passananti, Gary T. Burger, Elliot S. Vesell, George Howard, Carolyn A. Rahn, David J. Doolittle, Chin K. Lee, E. Riccio, A.W. Hayes
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 27(10)
The effects of cooking methods on the in vitro mutagenicity of individual foods, the in vitro mutagenicity of meals containing those foods, and the mutagenic exposure of human volunteers following consumption of the meals were examined using Ames bac