Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Carolyn A, Fairbanks"'
Autor:
Miles C. Smith, Lalitha R. Belur, Andrea D. Karlen, Olivia Erlanson, Justin Furcich, Troy C. Lund, Davis Seelig, Kelley F. Kitto, Carolyn A. Fairbanks, Kwi Hye Kim, Nick Buss, R. Scott McIvor
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 1, Pp 101201- (2024)
Mucopolysaccharidosis type II (MPS II) is an X-linked recessive lysosomal disease caused by iduronate-2-sulfatase (IDS) deficiency, leading to accumulation of glycosaminoglycans (GAGs) and the emergence of progressive disease. Enzyme replacement ther
Externí odkaz:
https://doaj.org/article/a2a8c79881364444bb7633c2c34e66ec
Autor:
Caroline C. Churchill, Cristina D. Peterson, Kelley F. Kitto, Kelsey R. Pflepsen, Lalitha R. Belur, R. Scott McIvor, Lucy Vulchanova, George L. Wilcox, Carolyn A. Fairbanks
Publikováno v:
Frontiers in Pain Research, Vol 4 (2024)
Agmatine, a decarboxylated form of L-arginine, prevents opioid analgesic tolerance, dependence, and self-administration when given by both central and systemic routes of administration. Endogenous agmatine has been previously detected in the central
Externí odkaz:
https://doaj.org/article/52efa26146094fbbb8d8e7459e96d505
Autor:
Christina M Larson, Cecilia Barajas, Kelley F Kitto, George L Wilcox, Carolyn A Fairbanks, Cristina D Peterson
Publikováno v:
PLoS ONE, Vol 19, Iss 3, p e0298819 (2024)
Buprenorphine in an extended-release formulation intended for use in laboratory subjects is frequently administered to rats to provide extended analgesia without repeated handling. While levels of buprenorphine may persist in serum once extended-rele
Externí odkaz:
https://doaj.org/article/8f8b209ddf5c4759a7b57fb4d45318e3
Publikováno v:
Frontiers in Pain Research, Vol 4 (2023)
Throughout history humanity has searched for an optimal approach to the use of opioids that maximizes analgesia while minimizing side effects. This review reflects upon the conceptualization of the opioid receptor and the critical role that the pharm
Externí odkaz:
https://doaj.org/article/bc811923188c4fef94552d55839b8b82
Autor:
Reshma Gore, Tina Esmail, Kelsey Pflepsen, Ezequiel Marron Fernandez de Velasco, Kelley F. Kitto, Maureen S. Riedl, Andrea Karlen, R. Scott McIvor, Christopher N. Honda, Carolyn A. Fairbanks, Lucy Vulchanova
Publikováno v:
Frontiers in Pain Research, Vol 4 (2023)
Investigation of neural circuits underlying visceral pain is hampered by the difficulty in achieving selective manipulations of individual circuit components. In this study, we adapted a dual AAV approach, used for projection-specific transgene expre
Externí odkaz:
https://doaj.org/article/267d366a68584b458e50530348ee8317
Autor:
Alexander G. J. Skorput, Reshma Gore, Rachel Schorn, Maureen S. Riedl, Ezequiel Marron Fernandez de Velasco, Bailey Hadlich, Kelley F. Kitto, Carolyn A. Fairbanks, Lucy Vulchanova
Publikováno v:
PLoS ONE, Vol 17, Iss 3 (2022)
Adeno-associated viral (AAV) vectors allow for site-specific and time-dependent genetic manipulation of neurons. However, for successful implementation of AAV vectors, major consideration must be given to the selection of viral serotype and route of
Externí odkaz:
https://doaj.org/article/6fb643af031c48b9a9569490d07460b9
Autor:
Lalitha R. Belur, Megan Romero, Junggu Lee, Kelly M. Podetz-Pedersen, Zhenhong Nan, Maureen S. Riedl, Lucy Vulchanova, Kelley F. Kitto, Carolyn A. Fairbanks, Karen F. Kozarsky, Paul J. Orchard, William H. Frey, Walter C. Low, R. Scott McIvor
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Mucopolysaccharidosis type I (MPS I) is an inherited metabolic disorder caused by deficiency of the lysosomal enzyme alpha-L-iduronidase (IDUA). The two current treatments [hematopoietic stem cell transplantation (HSCT) and enzyme replacement therapy
Externí odkaz:
https://doaj.org/article/612b20e3a1914626b04655208aae2b85
Autor:
Cristina D. Peterson, Jonathan J. Waataja, Kelley F. Kitto, Samuel J. Erb, Harsha Verma, Daniel J. Schuster, Caroline C. Churchill, Maureen S. Riedl, Lalitha R. Belur, Daniel A. Wolf, R. Scott McIvor, Lucy Vulchanova, George L. Wilcox, Carolyn A. Fairbanks
Publikováno v:
Molecular Therapy. 31:1123-1135
Autor:
Cristina D. Peterson, Lukas Caye, Kelley Kitto, George L. Wilcox, Laura Stone, Swati More, Carolyn A. Fairbanks
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Drug Discovery and Development.
Autor:
Tongzhen Xie, Rachel E. Schorn, Cristina D. Peterson, Lucy Vulchanova, George L. Wilcox, Carolyn A. Fairbanks
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Central Nervous System Pharmacology - Neuropharmacology.