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pro vyhledávání: '"Caroline Wingolf"'
Autor:
Stefan Oswald, Eva Mangelsen, Markus Keiser, Beatrice Kisser, Claus-Dieter Heidecke, Lars Ivo Partecke, Christer Tannergren, Caroline Wingolf
Publikováno v:
Current Protocols in Pharmacology
The Ussing chamber is an old but still powerful technique originally designed to study the vectorial transport of ions through frog skin. This technique is also used to investigate the transport of chemical agents through the intestinal barrier as we
Autor:
Anna-Lena Ungell, Christer Tannergren, Mareike Lutz, Anders Borde, Caroline Wingolf, Åsa Sjöberg
Publikováno v:
European Journal of Pharmaceutical Sciences. 48:166-180
The purpose of this study was to evaluate the use of human intestinal tissue in Ussing chamber to predict oral and colonic drug absorption and intestinal metabolism. Data on viability, correlation between apparent permeability coefficients (P(app)) a