Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Caroline Waltzinger"'
Autor:
Reinhard Dummer, Marina Bacac, Pablo Umana, Mitchell P Levesque, Christine Trumpfheller, Mi He, Bhavesh Soni, Petra C Schwalie, Tamara Hüsser, Caroline Waltzinger, Duvini De Silva, Ylva Prinz, Laura Krümpelmann, Samuele Calabro, Ines Matos, Maries van den Broek, Stephan Gasser
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/86af3a62742e4d618016ad79388f8eb6
Autor:
David Coelho, Patrick Dufour, Caroline Waltzinger, V. Holl, Pierre Bischoff, Jean-François Keyser, Luc Silbernagel
Publikováno v:
Biochemical Pharmacology. 60:1565-1577
The alkylating agent, nitrogen mustard (HN2), is thought to cause apoptosis through production of free oxygen radicals. To explore the mechanism of HN2-induced apoptosis, we utilized ebselen, a selenoorganic compound with potent antioxidant activity.
Autor:
Margarida Correia-Neves, Caroline Waltzinger, Jean-Marie Wurtz, Christophe Benoist, Diane Mathis
Publikováno v:
The Journal of Immunology. 163:5471-5477
Some TCR variable regions are preferentially expressed in CD4+ or CD8+ T cells, reflecting a predilection for interacting with MHC class II or class I molecules. The molecular basis for MHC class bias has been studied previously, in particular for V
Publikováno v:
European Journal of Immunology. 29:2916-2922
Combining CD5-null, MHC-deficient and lineage-specific reporter animals, we have investigated the influence of CD5 on positive selection and the choice of CD4- versus CD8-lineage commitment on broad populations of thymocytes. CD5 has no obvious quant
Publikováno v:
The EMBO Journal. 13:4482-4489
Recent experiments have re-awakened interest in a stochastic/selective model of positive selection of T lymphocytes. A revised version of the model has been proposed whereby commitment of double-positive thymocytes to either the CD4 or CD8 lineage re
Publikováno v:
European Journal of Immunology. 22:1765-1771
The expression of minor lymphocyte stimulatory locus (Mls) determinants in combination with murine major histocompatibility complex (MHC) class II molecules, leads to the destruction of lymphocytes bearing specific V region-encoded T cell receptor (T
Publikováno v:
International Immunology. 4:707-710
Our aim was to assess the generality of the observation that positive selection of CD4+ T cells is mediated by MHC class II molecules on epithelial cells of the thymic cortex. By appropriate matings of previously established transgenic and mutant mou
Publikováno v:
The Journal of Experimental Medicine
To ascertain how the actual repertoire of T cell receptors (TCRs) deviates from the theoretical, we have generated a large number of junctional region sequences from TCRs carrying the V beta 17 variable region. The greater than 600 sequences analyzed
Autor:
Matthias P. Wymann, Bart Vanhaesebroeck, Klaus Okkenhaug, Antonio Bilancio, Hong Ji, Thomas Rückle, Christian Rommel, Felix Rintelen, Emilio Hirsch, Wayne Pearce, Montserrat Camps, Caroline Waltzinger, Dominique Bertschy Meier
Publikováno v:
Blood. 110(8)
Mice lacking both the p110gamma and p110delta isoforms display severe impairment of thymocyte development. Here, we show that this phenotype is recapitulated in p110gamma-/-/p110delta(D910A/D910A) (p110gamma(KO)delta(D910A)) mice where the p110delta
Autor:
Caroline Waltzinger, Michel Dreano, Yves Sagot, P Jolicoeur, Angélique Heckmann, Marie Kosco-Vilbois
Publikováno v:
The American journal of pathology. 164(4)
Wasting and renal diseases are frequent complications of HIV (human immunodeficiency virus) infection and are associated with accelerated disease progression and increased mortality. Transgenic mice expressing HIV1 under control of the CD4 promoter d