Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Caroline Vouillac"'
Publikováno v:
eLife, Vol 10 (2021)
Delineating the decision-making mechanisms underlying choice between drug and nondrug rewards remains a challenge. This study adopts an original approach to probe these mechanisms by comparing response latencies during sampling versus choice trials.
Externí odkaz:
https://doaj.org/article/549bec5ffc324a91b07dd57eb6856941
Autor:
Michel Engeln, Serge H. Ahmed, Caroline Vouillac, François Tison, Erwan Bezard, Pierre-Olivier Fernagut
Publikováno v:
Neurobiology of Disease, Vol 49, Iss , Pp 79-86 (2013)
Striatal D2 and D3 dopamine receptors are involved in mediating the reinforcing properties of natural rewards and drugs. In Parkinson's disease, while D2/3 dopamine agonists alleviate motor symptoms, behavioral addictions and withdrawal syndrome are
Externí odkaz:
https://doaj.org/article/f2c79dbe00db45cd8b639599d5d6db7f
Autor:
Lauriane Cantin, Magalie Lenoir, Eric Augier, Nathalie Vanhille, Sarah Dubreucq, Fuschia Serre, Caroline Vouillac, Serge H Ahmed
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11592 (2010)
BackgroundAssessing the relative value of cocaine and how it changes with chronic drug use represents a long-standing goal in addiction research. Surprisingly, recent experiments in rats--by far the most frequently used animal model in this field--su
Externí odkaz:
https://doaj.org/article/79c0d3f70e0140b2bf9f5af8940f9fdd
Publikováno v:
Neuropsychopharmacology. 48:887-896
Nicotine addiction develops after prolonged drug use and escalation of drug intake. However, because of difficulties in demonstrating escalation of nicotine use in rats, its underlying neuroadaptations still remain poorly understood. Here we report t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3671cc0bbe8b6ee3025536cecceb54ca
https://doi.org/10.1038/s41386-022-01428-9
https://doi.org/10.1038/s41386-022-01428-9
Autor:
null Magalie Lenoir, null Sylvia Navailles, null Youna Vandaele, null Caroline Vouillac‐Mendoza, null Karine Guillem, null Serge H. Ahmed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1d7ba6f761c7c59703c96a79700b4d1
https://doi.org/10.1111/ejn.15879/v2/response1
https://doi.org/10.1111/ejn.15879/v2/response1
Publikováno v:
Addiction Biology. 27
When facing a choice, most animals quit drugs in favour of a variety of nondrug alternatives. We recently found, rather unexpectedly, that choice of the nondrug alternative is in fact inflexible and habitual. One possible contributing factor to habit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09d9303ddb3264592ef9409d69b60505
https://doi.org/10.1111/adb.13235
https://doi.org/10.1111/adb.13235
Autor:
Magalie Lenoir, Sylvia Navailles, Youna Vandaele, Caroline Vouillac-Mendoza, Karine Guillem, Serge H. Ahmed
Cocaine induces many supranormal changes in neuronal activity in the brain, notably in learning- and reward-related regions, in comparison to nondrug rewards - a difference that is thought to contribute to its relatively high addictive potential. How
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e00b634b00d1d09958b1936d41760ec2
https://hal.science/hal-03687064
https://hal.science/hal-03687064
Publikováno v:
eLife
eLife, eLife Sciences Publication, 2021, 10, ⟨10.7554/eLife.64993⟩
eLife, 2021, 10, ⟨10.7554/eLife.64993⟩
eLife, Vol 10 (2021)
eLife, eLife Sciences Publication, 2021, 10, ⟨10.7554/eLife.64993⟩
eLife, 2021, 10, ⟨10.7554/eLife.64993⟩
eLife, Vol 10 (2021)
Investigating the decision-making mechanisms underlying choice between drug and nondrug rewards is essential to understand how their alterations can contribute to substance use disorders. However, despite some recent effort, this investigation remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c6ec86947de4bfa617cd5fef1e794bb
https://hal.archives-ouvertes.fr/hal-03368485/document
https://hal.archives-ouvertes.fr/hal-03368485/document
Publikováno v:
Neuropsychopharmacology
Neuropsychopharmacology, Nature Publishing Group, 2020, ⟨10.1038/s41386-020-0786-9⟩
Neuropsychopharmacology, Nature Publishing Group, 2020, ⟨10.1038/s41386-020-0786-9⟩
International audience; Cocaine is known to increase brain dopamine at supranormal levels in comparison to alternative nondrug rewards. According to the dopamine hypothesis of addiction, this abnormally large dopamine response would explain why cocai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2b07bc999a0e303da7df8c8388d8550
https://hal.archives-ouvertes.fr/hal-03005480
https://hal.archives-ouvertes.fr/hal-03005480