Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Caroline V. Braem"'
Autor:
Boudewijn Van Damme, Isabelle Van Valckenborgh, Frederik Van Dyck, Jeroen Declercq, Wim J.M. Van de Ven, Marianne Voz, Caroline V. Braem, Laurence Fiette, Michel Wassef, Luc Schoonjans
Publikováno v:
Cancer Research. 65:4544-4553
Pleomorphic adenoma gene 1 (PLAG1) proto-oncogene overexpression is implicated in various human neoplasias, including salivary gland pleomorphic adenomas. To further assess the oncogenic capacity of PLAG1, two independent PLAG1 transgenic mouse strai
Autor:
Wim J.M. Van de Ven, Laurence Fiette, Jeroen Declercq, Karen Hensen, Carl Denef, Mieke Dewerchin, Frederik Van Dyck, Caroline V. Braem
Publikováno v:
Development, Growth and Differentiation. 46:459-470
The pleomorphic adenoma gene 1 (Plag1) proto-oncogene encodes a transcription factor and is implicated in human tumorigenesis via ectopic overexpression. No information is available about its developmental role. To address this, a Plag1-/- mouse stra
Publikováno v:
Journal of Biological Chemistry. 277:19673-19678
The activation of the pleomorphic adenoma gene 1 (PLAG1) is the most frequent gain-of-function mutation found in pleomorphic adenomas of the salivary glands. To gain more insight into the regulation of PLAG1 function, we searched for PLAG1-interactin
Publikováno v:
International Journal of Oncology.
Recent studies of human tumours as well as genetically engineered mouse tumour models have established the importance and versatility of the PLAG1 oncogene in tumourigenesis. The PLAG1 proto-oncogene was discovered by studying the t(3;8)(p21;ql2) chr
Publikováno v:
International journal of oncology. 30(4)
Recent studies of human tumours as well as genetically engineered mouse tumour models have established the importance and versatility of the PLAG1 oncogene in tumourigenesis. The PLAG1 proto-oncogene was discovered by studying the t(3;8)(p21;q12) chr
Autor:
Etienne Waelkens, Susumu Ito, Frederik Van Dyck, Rita Derua, Zhao Chen, Byeong-Moo Kim, Ramesh A. Shivdasani, Frans Schuit, Anton J.M. Roebroek, Wim J.M. Van de Ven, Mieke Dewerchin, Jeroen Declercq, Caroline V. Braem, Rob Deckers, Laurence Fiette, Michele K. Wu, David E. Cohen
Publikováno v:
Cell metabolism. 6(5)
SummaryEnterocytes assemble dietary lipids into chylomicron particles that are taken up by intestinal lacteal vessels and peripheral tissues. Although chylomicrons are known to assemble in part within membrane secretory pathways, the modifications re
Publikováno v:
International Congress Series. 1279:168-169
The expression ‘Cancer that cures can never be malignant’ is sometimes used to refer to benign tumours and although such tumours are not life threatening, they represent a significant burden for the health care system. This is due to the high fre