Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Caroline Twarog"'
Publikováno v:
Pharmaceutics, Vol 11, Iss 2, p 78 (2019)
Salcaprozate sodium (SNAC) and sodium caprate (C10) are two of the most advanced intestinal permeation enhancers (PEs) that have been tested in clinical trials for oral delivery of macromolecules. Their effects on intestinal epithelia were studied fo
Externí odkaz:
https://doaj.org/article/61d28a5973274b619d400f667a20c77e
Autor:
David J. Brayden, Kai Liu, Kenneth A. Dawson, Caroline Twarog, Brigitte Illel, Peter J. O'Brien, Elias Fattal
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 152:95-107
Salcaprozate sodium (SNAC) and sodium caprate (C10) are the two leading intestinal permeation enhancers (PEs) in oral peptide formulations in clinical trials. There is debate over their mechanism of action on intestinal epithelia. The aims were: (i)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::303f0c78babdb2e7696914d5a8735114
https://doi.org/10.1016/j.ejpb.2020.04.023
https://doi.org/10.1016/j.ejpb.2020.04.023
Autor:
Caroline, Twarog, Elias, Fattal, Magali, Noiray, Brigitte, Illel, David J, Brayden, Myriam, Taverna, Hervé, Hillaireau
Publikováno v:
International journal of pharmaceutics. 626
A common approach to tackle the poor intestinal membrane permeability of peptides after oral administration is to formulate them with a permeation enhancer (PE). Increased oral bioavailability for oral peptide candidates has been reported from clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::edf43da5833c5cee4995e94b8762f500
https://pubmed.ncbi.nlm.nih.gov/36028084
https://pubmed.ncbi.nlm.nih.gov/36028084
Autor:
Ravi Yadav, Hugh E. Giffney, Marc Farrelly, Aisling Fleming, Bridget V. Hogg, Meritxell B. Cutrona, Krutika Singh, Fergal O Meara, Colm Delaney, Caroline Twarog, Alison L. Reynolds, Niamh Geoghegan, Gwyneth MacMaster, Shreyas Phadke, Jacek K. Wychowaniec, Shada Ali Alsharif, Ayana Anandan, Sumesh Erikandath, Fiona McCartney, Samir A. Belhout, Sourav Bhattacharjee, Jasmin McCaul, Vivien Stuttgen, Jessica Mc-Fadden, Anwar Alabdali, Lucia Podhorska, Mark D Alton, Susan Gaines, Mark O Loughlin, Peter Coulahan, Sarinj Fattah, Nahlah Ahmed Al-Hadhrami
Publikováno v:
Nanotoxicology. 13:717-732
Careful handling of the nanomaterials (NMs) in research labs is crucial to ensure a safe working environment. As the largest university in Ireland, University College Dublin (UCD) has invested significant resources to update researchers working with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f4628d3bb9169bffbba521d3b8ee3c4
https://doi.org/10.1080/17435390.2019.1621402
https://doi.org/10.1080/17435390.2019.1621402
Autor:
Caroline, Twarog, Fiona, McCartney, Sabine M, Harrison, Brigitte, Illel, Elias, Fattal, David J, Brayden
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 158
SNAC and C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::29f43364407b74f7a8a07755f1bae010
https://pubmed.ncbi.nlm.nih.gov/33359131
https://pubmed.ncbi.nlm.nih.gov/33359131
Autor:
Caroline, Twarog, Kai, Liu, Peter J, O'Brien, Kenneth A, Dawson, Elias, Fattal, Brigitte, Illel, David J, Brayden
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 152
Salcaprozate sodium (SNAC) and sodium caprate (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c318fba50aad84f05ec32047e4f82ff8
https://pubmed.ncbi.nlm.nih.gov/32387703
https://pubmed.ncbi.nlm.nih.gov/32387703
Autor:
Fiona McCartney, Sabine M. Harrison, Brigitte Illel, Elias Fattal, Caroline Twarog, David J. Brayden
Publikováno v:
European Journal of Pharmaceutical Sciences. 158:105685
SNAC and C10 are intestinal permeation enhancers (PEs) used in formulations of peptides for oral delivery in clinical trials. Our aims were to compare their: (i) mechanism of action in isolated rat intestinal mucosae mounted in Ussing chambers and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f02fa27e823134871d5fcf6305b7c9f
https://doi.org/10.1016/j.ejps.2020.105685
https://doi.org/10.1016/j.ejps.2020.105685
Publikováno v:
Pharmaceutics
Pharmaceutics, Vol 11, Iss 2, p 78 (2019)
Pharmaceutics, Vol 11, Iss 2, p 78 (2019)
Salcaprozate sodium (SNAC) and sodium caprate (C10) are two of the most advanced intestinal permeation enhancers (PEs) that have been tested in clinical trials for oral delivery of macromolecules. Their effects on intestinal epithelia were studied fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d980e4df5746bf19ed178864f4556d