Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Caroline Sirjusingh"'
Autor:
Lucas S. Parreiras, Jason M. Funt, Amanda Socha, Linda M. Kohn, Caroline Sirjusingh, James B. Anderson, David S. Guttman, Dawn A. Thompson, Snehit Prabhu, Aviv Regev, Jeremy R. Dettman
Publikováno v:
Current Biology. 20:1383-1388
Divergent adaptation can be associated with reproductive isolation in the process of speciation [1]. We recently demonstrated the link between divergent adaptation and the onset of reproductive isolation in experimental populations of the yeast Sacch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb9f2dc05e888eaa025bd6fcfb959857
https://doi.org/10.1016/j.cub.2010.06.022
https://doi.org/10.1016/j.cub.2010.06.022
Publikováno v:
Nature. 447:585-588
Establishing the conditions that promote the evolution of reproductive isolation and speciation has long been a goal in evolutionary biology. In ecological speciation, reproductive isolation between populations evolves as a by-product of divergent se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0d4db4ae33f233f52ce54bfcbe72144
https://doi.org/10.1038/nature05856
https://doi.org/10.1038/nature05856
Publikováno v:
Eukaryotic Cell. 5:1243-1251
This study tested for interaction between two independently evolved mechanisms of fluconazole resistance in Saccharomyces cerevisiae . One set of strains was from a 400-generation evolution experiment, during which the concentration of fluconazole wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e9c207c9295e89d890f2fb0dd6e77da
https://doi.org/10.1128/ec.00048-06
https://doi.org/10.1128/ec.00048-06
Autor:
Caroline Sirjusingh, Claire Wickens, Ainslie B. Parsons, Leah E. Cowen, Linda M. Kohn, James B. Anderson, Charles Boone
Publikováno v:
Genetics. 163:1287-1298
We show that mode of selection, degree of dominance of mutations, and ploidy are determining factors in the evolution of resistance to the antifungal drug fluconazole in yeast. In experiment 1, yeast populations were subjected to a stepwise increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb8eef77cb0a40c90e541435529cad92
https://doi.org/10.1093/genetics/163.4.1287
https://doi.org/10.1093/genetics/163.4.1287
Publikováno v:
Journal of Clinical Microbiology. 39:1657-1660
Multilocus genotyping was used to compare populations of Candida albicans from oral mucosa and blood. No significant differences in allele frequencies between the two samples were detected, and in a dendrogram of genotypic similarities, genotypes fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd7381b440bae8859190571be12c1947
https://doi.org/10.1128/jcm.39.4.1657-1660.2001
https://doi.org/10.1128/jcm.39.4.1657-1660.2001
Autor:
James B. Anderson, Richard C. Summerbell, Susan E. Richardson, Leah E. Cowen, Sharon Walmsley, Linda M. Kohn, Caroline Sirjusingh
Publikováno v:
Antimicrobial Agents and Chemotherapy. 43:2930-2938
If variation in azole resistance is due to inherent differences in strains of Candida albicans , as a predominantly clonal organism, then correlation between multilocus genotypes and drug resistance would be expected. A sample of 81 clinical isolates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::347fe7520243cbe419bc65e0f39196c2
https://doi.org/10.1128/aac.43.12.2930
https://doi.org/10.1128/aac.43.12.2930
Autor:
Caroline Sirjusingh, Linda M. Kohn
Publikováno v:
Molecular Ecology Notes. 1:267-269
Twenty-five primers produced unambiguous amplification products of 23 microsatellite-containing loci and two microsatellite-like polymorphic loci, with 2–10 alleles at each locus in the plant pathogenic fungus, Sclerotinia sclerotiorum. Haplotypes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::792c0a2e784e42fe0414d9e86441f995
https://doi.org/10.1046/j.1471-8278.2001.00102.x
https://doi.org/10.1046/j.1471-8278.2001.00102.x
Permanent changes in gene expression result from certain forms of antifungal resistance. In this study, we asked whether any changes in gene expression are required for the evolution of a drug-resistant phenotype in populations. We examined the chang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a8ee230d2f89e7dca80692cfef86b0a
https://europepmc.org/articles/PMC2681570/
https://europepmc.org/articles/PMC2681570/
We tested the hypothesis that the time course of the evolution of antifungal drug resistance depends on the ploidy of the fungus. The experiments were designed to measure the initial response to the selection imposed by the antifungal drug fluconazol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66379792d2c6a5f7eb4185cb86169fe8
https://europepmc.org/articles/PMC1448728/
https://europepmc.org/articles/PMC1448728/