Výsledky vyhledávání - "Caroline S.-J. Wei"

Loss of Heterozygosity and Internal Tandem Duplication Mutations of the CBP Gene Are Frequent Events in Human Esophageal Squamous Cell Carcinoma

Autor: Chung S. Yang, Yan Nie, Norman A. Doggett, Li Dong Wang, Guang Yu Yang, Caroline S.-J. Wei, Suzie Chen, Chi Kwong So, Yunlong Song

Publikováno v: Clinical Cancer Research. 10:19-27

Purpose: Cyclic AMP response element binding protein binding protein (CBP), a nuclear transcriptional coactivator protein, is an important component of the cAMP signal transduction pathway. In this study, we systematically analyzed the pattern and fr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa8be26e127f970c809a6e7c895c3b8f
https://doi.org/10.1158/1078-0432.ccr-03-0160

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A Single Site-specific trans-Opened 7,8,9,10-Tetrahydrobenzo[a]pyrene 7,8-Diol 9,10-EpoxideN2-Deoxyguanosine Adduct Induces Mutations at Multiple Sites in DNA

Autor: Barbara Zajc, Pavel Kramata, Jane M. Sayer, Caroline S.-J. Wei, Donald M. Jerina

Publikováno v: Journal of Biological Chemistry. 278:14940-14948

Site-specific mutagenicity of trans-opened adducts at the exocyclic N(2)-amino group of guanine by the (+)-(7R,8S,9S,10R)- and (-)-(7S,8R,9R,10S)-enantiomers of a benzo[a]pyrene 7,8-diol 9,10-epoxide (7-hydroxyl and epoxide oxygen are trans, BPDE-2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7498d6738b0bb4fbd7f148d8270b339b
https://doi.org/10.1074/jbc.m211557200

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Benzo[a]pyrene diol epoxide-deoxyguanosine adducts are accurately bypassed by yeast DNA polymerase zeta in vitro

Autor: Caroline S.-J. Wei, Donald M. Jerina, David C. Hinkle, Barbara Zajc, Jane M. Sayer, Srilatha Simhadri, Pavel Kramata

Publikováno v: Mutation research. 508(1-2)

The possible role of bypass DNA polymerase zeta in mutagenic translesion synthesis past benzo[a]pyrene (BP) 7,8-diol-9,10-epoxide (DE) N(2)-deoxyguanosine (dG) adducts has been examined. We prepared 59-mer DNA templates containing dG adducts derived

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b158cf577fb488b3981b9d8ad37780e4
https://pubmed.ncbi.nlm.nih.gov/12379469

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Erratum to 'Benzo[a]pyrene diol epoxide–deoxyguanosine adducts are accurately bypassed by yeast DNA polymerase ζ in vitro' [Mutat. Res. 508 (2002) 137–145]

Autor: Caroline S.-J. Wei, Barbara Zajc, Donald M. Jerina, David C. Hinkle, Jane M. Sayer, Srilatha Simhadri, Pavel Kramata

Publikováno v: Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 525:131

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::99d3e5d5a0b40720c2575d805181fe3f
https://doi.org/10.1016/s0027-5107(02)00308-1

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