Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Caroline S. Jansen"'
Circulating Tumor DNA in Genitourinary Cancers: Detection, Prognostics, and Therapeutic Implications
Publikováno v:
Cancers, Vol 16, Iss 12, p 2280 (2024)
CtDNA is emerging as a non-invasive clinical detection method for several cancers, including genitourinary (GU) cancers such as prostate cancer, bladder cancer, and renal cell carcinoma (RCC). CtDNA assays have shown promise in early detection of GU
Externí odkaz:
https://doaj.org/article/752cf948eb114428994ef8fb1e0b9028
Autor:
Caroline S. Jansen, Yujin Choi, Sean T. Evans, Rachel Greenwald, Joseph A. Behnke, Caitlin Hartman, Haydn Kissick, Lara R. Harik, Mehmet Asim Bilen
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Extrarenal clear cell renal cell carcinoma (eccRCC) is a rare type of RCC that arises in areas other than the kidney. Given its rarity, consensus guidelines for optimal treatment of eccRCC have not been established, and the literature is lacking any
Externí odkaz:
https://doaj.org/article/b957ea377e384a84a09b869d05f9bc07
Autor:
Dylan J. Martini, Caroline S. Jansen, Lara R. Harik, Sean T. Evans, T. Anders Olsen, Viraj A. Master, Haydn T. Kissick, Mehmet Asim Bilen
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Translocation-associated renal cell carcinoma (tRCC) is a rare, aggressive malignancy that primarily affects children and young adults. There is no clear consensus on the most effective treatment for tRCC and there are no biomarkers of response to tr
Externí odkaz:
https://doaj.org/article/da6ce88eaca443b4b36d698e6a2035ef
Autor:
Mehmet A. Bilen, James F. Jiang, Caroline S. Jansen, Jacqueline T. Brown, Lara R. Harik, Aarti Sekhar, Haydn Kissick, Shishir K. Maithel, Omer Kucuk, Bradley Carthon, Viraj A. Master
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
IntroductionCabozantinib (XL-184) is a small molecule inhibitor of the tyrosine kinases c-Met, AXL, and VEGFR2 that has been shown to reduce tumor growth, metastasis, and angiogenesis. After the promising results from the METEOR and CABOSUN trials, c
Externí odkaz:
https://doaj.org/article/9bd82e94fe14462488e08962f8af3568
Autor:
Camilla Margaroli, Maria A. Cardenas, Caroline S. Jansen, Adriana Moon Reyes, Fares Hosseinzadeh, Gordon Hong, Yilin Zhang, Haydn Kissick, Rabindra Tirouvanziam, Viraj A. Master
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Infiltrating tumor neutrophils and myeloid-derived suppressor cells represent major populations in the tumor microenvironment that contribute to tumor progression. However, the phenotype of circulating and tumor-associated neutrophils, and the impact
Externí odkaz:
https://doaj.org/article/5283fdc8f8d9452a9f047350ce83a0a6
Autor:
Joshua D Preston, Caroline S Jansen, Siddhartha Kosaraju, Tim Niyogusaba, Tony Z Zhuang, Sally W Iwamoto, Spencer K Hutto, Mary Jo Lechowicz, Pamela B Allen
Publikováno v:
CNS Oncology, Vol 12, Iss 4 (2023)
Cutaneous T-cell lymphoma (CTCL) is a rare hematologic malignancy that traditionally presents with cutaneous lesions, though metastases are not uncommon in progressive disease. We describe four cases of CTCL with central nervous system (CNS) involvem
Externí odkaz:
https://doaj.org/article/ce62795458fd4bc6bd9c6d5b640eaa7e
Autor:
David J. Einstein, Steven P. Balk, Adam G. Sowalsky, Haydn Kissick, Sabina Signoretti, Huihui Ye, Philip J. Saylor, David B. Sykes, Olga Voznesensky, Anson T. Ku, Ross Lake, Scott Wilkinson, Luke del Balzo, Taghreed Hirz, Caroline S. Jansen, Miriam Ficial, Carla Calagua
Purpose:A subset of primary prostate cancer expresses programmed death-ligand 1 (PD-L1), but whether they have a unique tumor immune microenvironment or genomic features is unclear.Experimental Design:We selected PD-L1–positive high-grade and/or hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36a7b22af536c2e4eaf7236bc4e0e466
https://doi.org/10.1158/1078-0432.c.6530387.v1
https://doi.org/10.1158/1078-0432.c.6530387.v1
Autor:
David J. Einstein, Steven P. Balk, Adam G. Sowalsky, Haydn Kissick, Sabina Signoretti, Huihui Ye, Philip J. Saylor, David B. Sykes, Olga Voznesensky, Anson T. Ku, Ross Lake, Scott Wilkinson, Luke del Balzo, Taghreed Hirz, Caroline S. Jansen, Miriam Ficial, Carla Calagua
Supplementary Data from A Subset of Localized Prostate Cancer Displays an Immunogenic Phenotype Associated with Losses of Key Tumor Suppressor Genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4abfd00712f3fea0f384cc9a84b9731a
https://doi.org/10.1158/1078-0432.22480184.v1
https://doi.org/10.1158/1078-0432.22480184.v1
Autor:
Jennifer Wilkinson Carlisle, Caroline S Jansen, Maria Andrea Cardenas, Ewelina Sobierajska, Adriana Moon Reyes, Rachel Greenwald, Luke Del Balzo, Nataliya Prokhnevska, Omer Kucuk, Bradley C Carthon, Patrick Connor Mullane, Adeboye Osunkoya, Deborah Baumgarten, Fares Hosseinzadeh, Scott Wilkinson, Ross Lake, Adam G Sowalsky, Yuan Liu, Viraj A Master, Mehmet A Bilen, Haydn Kissick
Publikováno v:
Journal for immunotherapy of cancer. 10(7)
PurposeCheckpoint therapy is now the cornerstone of treatment for patients with renal cell carcinoma (RCC) with advanced disease, but biomarkers are lacking to predict which patients will benefit. This study proposes potential immunological biomarker
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundCD4 T cells can differentiate into multiple effector subsets that can mediate variable functions. In this work we aim to understand how CD4 T cells differentiate in response to tumor antigens and their respective function in the anti-tumor