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pro vyhledávání: '"Caroline S. Galloway"'
Autor:
David A. Jackson, Richard E. Randall, Marian J. Killip, Caroline S. Galloway, Rupert J. Russell
Publikováno v:
Virology. 396:94-105
A panel of influenza A viruses encoding mutant NS1 proteins was created in which a number of NS1 functions, including interactions with dsRNA, PI3K, CPSF30 and PKR, were inhibited. Surprisingly, given previous reports that NS1 activates PI3K to preve
Autor:
Richard E. Randall, B. Precious, David A. Jackson, Richard M. Elliott, Axel Knebel, Benjamin G. Hale, Catherine H. Botting, Caroline S. Galloway
Publikováno v:
Virology. 383:6-11
Posttranslational modification of viral proteins by cellular enzymes is a feature of many virus replication strategies. Here, we report that during infection the multifunctional human influenza A virus NS1 protein is phosphorylated at threonine-215.