Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Caroline S de Freitas"'
Autor:
Suelen Silva Gomes Dias, Vinicius Cardoso Soares, André C Ferreira, Carolina Q Sacramento, Natalia Fintelman-Rodrigues, Jairo R Temerozo, Lívia Teixeira, Marcos Alexandre Nunes da Silva, Ester Barreto, Mayara Mattos, Caroline S de Freitas, Isaclaudia G Azevedo-Quintanilha, Pedro Paulo A Manso, Milene D Miranda, Marilda Mendonça Siqueira, Eugenio D Hottz, Camila R R Pão, Dumith C Bou-Habib, Debora F Barreto-Vieira, Fernando A Bozza, Thiago M L Souza, Patricia T Bozza
Publikováno v:
PLoS Pathogens, Vol 16, Iss 12, p e1009127 (2020)
Viruses are obligate intracellular parasites that make use of the host metabolic machineries to meet their biosynthetic needs. Thus, identifying the host pathways essential for the virus replication may lead to potential targets for therapeutic inter
Externí odkaz:
https://doaj.org/article/efc5a0370f864f88af78a38a55522ac3
Autor:
Caroline S de Freitas, Luiza M Higa, Carolina Q Sacramento, André C Ferreira, Patrícia A Reis, Rodrigo Delvecchio, Fabio L Monteiro, Giselle Barbosa-Lima, Harrison James Westgarth, Yasmine Rangel Vieira, Mayara Mattos, Natasha Rocha, Lucas Villas Bôas Hoelz, Rennan Papaleo Paes Leme, Mônica M Bastos, Gisele Olinto L Rodrigues, Carla Elizabeth M Lopes, Celso Martins Queiroz-Junior, Cristiano X Lima, Vivian V Costa, Mauro M Teixeira, Fernando A Bozza, Patrícia T Bozza, Nubia Boechat, Amilcar Tanuri, Thiago Moreno L Souza
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 1, p e0007072 (2019)
Yellow fever virus (YFV) is a member of the Flaviviridae family. In Brazil, yellow fever (YF) cases have increased dramatically in sylvatic areas neighboring urban zones in the last few years. Because of the high lethality rates associated with infec
Externí odkaz:
https://doaj.org/article/fb1141d18f444957aaf5642320fe32a5
Autor:
Carolina Q Sacramento, Andressa Marttorelli, Natalia Fintelman-Rodrigues, Caroline S de Freitas, Gabrielle R de Melo, Marco E N Rocha, Carlos R Kaiser, Katia F Rodrigues, Gisela L da Costa, Cristiane M Alves, Osvaldo Santos-Filho, Jussara P Barbosa, Thiago Moreno L Souza
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139236 (2015)
The influenza virus causes acute respiratory infections, leading to high morbidity and mortality in groups of patients at higher risk. Antiviral drugs represent the first line of defense against influenza, both for seasonal infections and pandemic ou
Externí odkaz:
https://doaj.org/article/a523b7b30b5c4fedbf86ba2719c78c7f
Autor:
Carolina Q Sacramento, Andressa Marttorelli, Natalia Fintelman-Rodrigues, Caroline S de Freitas, Gabrielle R de Melo, Marco E N Rocha, Carlos R Kaiser, Katia F Rodrigues, Gisela L da Costa, Cristiane M Alves, Osvaldo Santos-Filho, Jussara P Barbosa, Thiago Moreno L Souza
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0142246 (2015)
Externí odkaz:
https://doaj.org/article/0bcc95db16a64a3b923c99591e9fc19a
Autor:
André C. Ferreira, Carolina Q. Sacramento, Filipe S. Pereira-Dutra, Natália Fintelman-Rodrigues, Priscila P. Silva, Mayara Mattos, Caroline S. de Freitas, Andressa Marttorelli, Gabrielle R. de Melo, Mariana M. Campos, Isaclaudia G. Azevedo-Quintanilha, Aluana S. Carlos, João Vítor Emídio, Cristiana C. Garcia, Patrícia T. Bozza, Fernando A. Bozza, Thiago M. L. Souza
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
IntroductionInfluenza A virus (IAV) is one of the leading causes of respiratory tract infections in humans, representing a major public health concern. The various types of cell death have a crucial role in IAV pathogenesis because this virus may tri
Externí odkaz:
https://doaj.org/article/0836dd826fee4902a18acb63980080a8
Autor:
Otávio Augusto Chaves, Carlyle Ribeiro Lima, Natalia Fintelman-Rodrigues, Carolina Q. Sacramento, Caroline S. de Freitas, Leonardo Vazquez, Jairo R. Temerozo, Marco E.N. Rocha, Suelen S.G. Dias, Nicolas Carels, Patrícia T. Bozza, Hugo Caire Castro-Faria-Neto, Thiago Moreno L. Souza
Publikováno v:
International Journal of Biological Macromolecules. 222:1015-1026
Despite the fast development of vaccines, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) still circulates through variants of concern (VoC) and escape the humoral immune response. SARS-CoV-2 has provoked over 200,000 deaths/months s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fea9d0bb0cc054bc600a4844c99ea683
https://doi.org/10.1016/j.ijbiomac.2022.09.204
https://doi.org/10.1016/j.ijbiomac.2022.09.204
Autor:
Camila R. R. Pão, Thomas Tuschl, Aitor Garzia, Lucas Villas Bôas Hoelz, Felipe Betoni Saraiva, Suelen da Silva Gomes Dias, Dumith Chequer Bou-Habib, Frederico Silva Castelo Branco, Wei Xie, Jingyue Ju, Chuanjuan Tao, Vinicius Cardoso Soares, André C. Ferreira, Stevens K. Rehen, Jairo R. Temerozo, Caroline S. de Freitas, Carine dos Santos da Silva, Carolina Q. Sacramento, Marília Zaluar P. Guimarães, Andrew Owen, Thiago Moreno L. Souza, Patrícia T. Bozza, Xuanting Wang, Nubia Boechat, Mayara Mattos, Rajith K. R. Rajoli, Dinshaw J. Patel, Steffen Jockusch, Marcelo Alves Ferreira, Fernando A. Bozza, Natalia Fintelman-Rodrigues, Gabriela Vitória, Livia Goto-Silva, Tácio Vinício Amorim Fernandes, Aline de Paula Dias Da Silva, Mônica M. Bastos, Carolina da S. G. Pedrosa, Leticia R. Q. Souza, James J. Russo, Minchen Chien
Publikováno v:
Journal of Antimicrobial Chemotherapy
Background Current approaches of drug repurposing against COVID-19 have not proven overwhelmingly successful and the SARS-CoV-2 pandemic continues to cause major global mortality. SARS-CoV-2 nsp12, its RNA polymerase, shares homology in the nucleotid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ba3878b9eb5f2dd7bdc20ace00f834b
https://doi.org/10.1093/jac/dkab072
https://doi.org/10.1093/jac/dkab072
Autor:
André C. Ferreira, Carolina Q. Sacramento, Filipe S. Pereira-Dutra, Natália Fintelman-Rodrigues, Priscila P. Silva, Mayara Mattos, Caroline S. de Freitas, Andressa Marttorelli, Gabrielle R. de Melo, Mariana C. Macedo, Isaclaudia G. Azevedo-Quintanilha, Aluana S. Carlos, João Vitor Emídio, Cristiana C. Garcia, Patrícia T. Bozza, Fernando A. Bozza, Thiago M. L. Souza
Influenza A virus (IAV) causes a major public health concern, because it is one of the leading causes of respiratory tract infections and hospitalization. Severe influenza has been associated with the cytokine storm, and IAV productive infection cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ae1cf5c59681843ac37ba090fbc8d6b
https://doi.org/10.1101/2022.04.20.488871
https://doi.org/10.1101/2022.04.20.488871
Autor:
Lívia Teixeira, Jairo R. Temerozo, Filipe S. Pereira-Dutra, André Costa Ferreira, Mayara Mattos, Barbara Simonson Gonçalves, Carolina Q. Sacramento, Lohanna Palhinha, Tamires Cunha-Fernandes, Suelen S. G. Dias, Vinicius Cardoso Soares, Ester A. Barreto, Daniella Cesar-Silva, Natalia Fintelman-Rodrigues, Camila R. R. Pão, Caroline S. de Freitas, Patrícia A. Reis, Eugenio D. Hottz, Fernando A. Bozza, Dumith C. Bou-Habib, Elvira M. Saraiva, Cecília J. G. de Almeida, João P. B. Viola, Thiago Moreno L. Souza, Patricia T. Bozza
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Coronavirus disease 2019 (COVID-19) is currently a worldwide emergency caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). In observational clinical studies, statins have been identified as beneficial to hospitalized patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad3bf0914ce8aa3f2dcb596bd67fe52c
Autor:
Carolina Q. Sacramento, Jairo R. Temerozo, Suelen da Silva Gomes Dias, Franklin Souza da Silva, Caroline S. de Freitas, Carlos Roberto Alves, Vinicius Cardoso Soares, Aline R. Matos, Marilda M. Siqueira, Natalia Fintelman-Rodrigues, André C. Ferreira, Thiago Moreno L. Souza, Milene D. Miranda, Patrícia T. Bozza, Mayara Mattos, Carlyle Ribeiro Lima, Nicolas Carels, Fernando A. Bozza
Publikováno v:
Antimicrobial Agents and Chemotherapy
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is already responsible for far more deaths than previous pathogenic coronaviruses (CoVs) from 2002 and 2012. The identification of clinically approved drugs to be repurposed to combat 2019
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::719090f320c41ea15d27741b4d08f511