Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Caroline S Kinter"'
Autor:
Caroline S Kinter, Jillian M Lundie, Halee Patel, Paul M Rindler, Luke I Szweda, Michael Kinter
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50016 (2012)
The loading of macrophages with oxidized low density lipoprotein (LDL) is a key part of the initiation and progression of atherosclerosis. Oxidized LDL contains a wide ranging set of toxic species, yet the molecular events that allow macrophages to w
Externí odkaz:
https://doaj.org/article/2aae578d3a9648ef8a5e1bd179147ea8
Autor:
Willard M. Freeman, Kaitlyn Street, Michael Kinter, Caroline S. Kinter, Jonathan D. Wren, Rojina Ranjit, Katarzyna M. Piekarz, Arlan Richardson, Holly Van Remmen, Constantin Georgescu, Jacob L. Brown, Gavin Pharaoh, Kavithalakshmi Sataranatarajan
Publikováno v:
GeroScience
Mice lacking the superoxide anion scavenger CuZn superoxide dismutase (Sod1(−/−) mice) develop a number of age-related phenotypes, including an early progression of muscle atrophy and weakness (sarcopenia) associated with loss of innervation. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80a9e12d4f4e6a41a61080e44d137ea5
https://doi.org/10.1007/s11357-020-00189-x
https://doi.org/10.1007/s11357-020-00189-x
Autor:
Michael Kinter, Craig Eyster, Jennifer R. Giorgione, Satoshi Matsuzaki, Kenneth M. Humphries, Zachary T. Young, Caroline S. Kinter, Maria F. Newhardt
Publikováno v:
Redox Biology, Vol 47, Iss, Pp 102140-(2021)
Redox Biology
Redox Biology
Diabetic cardiomyopathy is associated with an increase in oxidative stress. However, antioxidant therapy has shown a limited capacity to mitigate disease pathology. The molecular mechanisms responsible for the modulation of reactive oxygen species (R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7854ebe1b376ca712f9264fee0a12d78
https://doi.org/10.1016/j.redox.2021.102140
https://doi.org/10.1016/j.redox.2021.102140
Autor:
Kenneth M. Humphries, Jennifer R. Giorgione, Satoshi Matsuzaki, Michael Kinter, Caroline S. Kinter, Lee B. Bockus, Shraddha S. Vadvalkar, Craig Eyster
Publikováno v:
Journal of Biological Chemistry. 292:4423-4433
Alterations in mitochondrial function contribute to diabetic cardiomyopathy. We have previously shown that heart mitochondrial proteins are hyperacetylated in OVE26 mice, a transgenic model of type 1 diabetes. However, the universality of this modifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e7e661b343b037276eea34caf784757
https://doi.org/10.1074/jbc.m116.753509
https://doi.org/10.1074/jbc.m116.753509
Autor:
Michael Kinter, Shauna Hill, Jake Gregston, Caroline S. Kinter, Gavin Pharaoh, Holly Van Remmen, Kavithalakshmi Sataranatarajan, Bumsoo Ahn, Kaitlyn Street
Publikováno v:
Frontiers in Neuroscience
Frontiers in Neuroscience, Vol 13 (2019)
Frontiers in Neuroscience, Vol 13 (2019)
Many Amyotrophic Lateral Sclerosis (ALS) patients experience hypermetabolism, or an increase in measured vs. calculated metabolic rate. The cause of hypermetabolism and the effects on neuronal metabolism in ALS are currently unknown, but the efficacy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c288bc04d5ff5c1b145292f0c16103c
http://europepmc.org/articles/PMC6554287
http://europepmc.org/articles/PMC6554287
Autor:
Zachary T. Young, Catherine A. Makarewich, Abdallah Elnwasany, Michael Kinter, Luke I. Szweda, Caroline S. Kinter, Christopher M. Schafer
Cardiac energy is produced primarily by oxidation of fatty acids and glucose, with the relative contributions of each nutrient being sensitive to changes in substrate availability and energetic demand. A major contributor to cardiac metabolic flexibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84e04c57cf3b7d2374295ec88a283e46
https://europepmc.org/articles/PMC5936801/
https://europepmc.org/articles/PMC5936801/
Autor:
Alexis Weddle, Luke I. Szweda, Caroline S. Kinter, Timothy Mather, Michael Kinter, Jolyn Fernandes, Kenneth M. Humphries
Publikováno v:
Biochemistry. 54(25)
High-throughput proteomics studies have identified several thousand acetylation sites on more than 1000 proteins. Mitochondrial aconitase, the Krebs cycle enzyme that converts citrate to isocitrate, has been identified in many of these reports. Acety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a3a69a25ef85183bbc1d7aec94596b0
https://pubmed.ncbi.nlm.nih.gov/26061789
https://pubmed.ncbi.nlm.nih.gov/26061789
Autor:
Michael Kinter, Caroline S. Kinter
A key experiment in biomedical research is monitoring the expression of different proteins in order to detect changes that occur in biological systems under different experimental conditions. The method that is most widely used is the Western blot a
Autor:
Caroline S. Kinter, Michael Kinter
Publikováno v:
Application of Selected Reaction Monitoring to Highly Multiplexed Targeted Quantitative Proteomics ISBN: 9781461486657
Selected reaction monitoring uses tandem mass spectrometry to create instrumental conditions where only specific peptides can be detected. The two stages of the mass spectrometer are synchronized so that a signal is seen only when a molecular ion wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7ddfb2124c576381fbc92d25a88b7a3
https://doi.org/10.1007/978-1-4614-8666-4_2
https://doi.org/10.1007/978-1-4614-8666-4_2
Autor:
Caroline S. Kinter, Michael Kinter
Publikováno v:
Application of Selected Reaction Monitoring to Highly Multiplexed Targeted Quantitative Proteomics ISBN: 9781461486657
The use of mass spectrometry for quantitative analysis began with the very first published experiment in 1913. Therefore, current applications, including quantitative proteomics, are based on an extensive foundation of fundamental and applied investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93fe6eb9295fcd608a43bce7b8029008
https://doi.org/10.1007/978-1-4614-8666-4_1
https://doi.org/10.1007/978-1-4614-8666-4_1