Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Caroline S Jansen"'
Autor:
Sean T Evans, Yash Jani, Caroline S Jansen, Ahmet Yildirim, Ecem Kalemoglu, Mehmet Asim Bilen
Publikováno v:
Cancer Biology & Therapy, Vol 25, Iss 1 (2024)
ABSTRACTThe introduction of novel immunotherapies has significantly transformed the treatment landscape of genitourinary (GU) cancers, even becoming the standard of care in some settings. One such type of immunotherapy, immune checkpoint inhibitors (
Externí odkaz:
https://doaj.org/article/082b3f99543f4a1ea7b9fa6358747071
Autor:
Seema Mustafa, Caroline S Jansen, Yash Jani, Sean Evans, Tony Z Zhuang, Jacqueline Brown, Bassel Nazha, Viraj Master, Mehmet Asim Bilen
Publikováno v:
Biomarker Insights, Vol 19 (2024)
In the past decade, immune checkpoint inhibitors (ICI) have been approved for treatment of genitourinary malignancies and have revolutionized the treatment landscape of these tumors. However, despite the remarkable success of these therapies in some
Externí odkaz:
https://doaj.org/article/017274fc0bba4e15975ffecd899cb669
Autor:
Haydn Kissick, Viraj A Master, Mehmet A Bilen, Zachary S Buchwald, Mohammad K Khan, Caroline S Jansen, Michael C Lowe, Jimmy S Patel, Yena Woo, Amber Draper, Jennifer W Carlisle, Pasquale F Innominato, Francis A Lévi, Layla Dhabaan, David C Qian
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 3 (2024)
Background Recent studies have demonstrated that earlier time-of-day infusion of immune checkpoint inhibitors (ICIs) is associated with longer progression-free survival (PFS) and overall survival (OS) among patients with metastatic melanoma and non-s
Externí odkaz:
https://doaj.org/article/daa2d9d9173340d48a63f3613635074f
Autor:
Joshua D Preston, Caroline S Jansen, Siddhartha Kosaraju, Tim Niyogusaba, Tony Z Zhuang, Sally W Iwamoto, Spencer K Hutto, Mary Jo Lechowicz, Pamela B Allen
Publikováno v:
CNS Oncology, Vol 12, Iss 4 (2023)
Cutaneous T-cell lymphoma (CTCL) is a rare hematologic malignancy that traditionally presents with cutaneous lesions, though metastases are not uncommon in progressive disease. We describe four cases of CTCL with central nervous system (CNS) involvem
Externí odkaz:
https://doaj.org/article/ce62795458fd4bc6bd9c6d5b640eaa7e
Autor:
Yuan Liu, Haydn Kissick, Viraj A Master, Mehmet A Bilen, Omer Kucuk, Bradley C Carthon, Nataliya Prokhnevska, Ewelina Sobierajska, Rachel Greenwald, Adeboye Osunkoya, Jennifer Wilkinson Carlisle, Caroline S Jansen, Maria Andrea Cardenas, Adriana Moon Reyes, Luke Del Balzo, Patrick Connor Mullane, Deborah Baumgarten, Fares Hosseinzadeh, Scott Wilkinson, Ross Lake, Adam G Sowalsky
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 7 (2022)
Purpose Checkpoint therapy is now the cornerstone of treatment for patients with renal cell carcinoma (RCC) with advanced disease, but biomarkers are lacking to predict which patients will benefit. This study proposes potential immunological biomarke
Externí odkaz:
https://doaj.org/article/7d09b80d31d542029330312b9c2f2744
Autor:
Dylan J. Martini, Caroline S. Jansen, Lara R. Harik, Sean T. Evans, T. Anders Olsen, Viraj A. Master, Haydn T. Kissick, Mehmet Asim Bilen
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Translocation-associated renal cell carcinoma (tRCC) is a rare, aggressive malignancy that primarily affects children and young adults. There is no clear consensus on the most effective treatment for tRCC and there are no biomarkers of response to tr
Externí odkaz:
https://doaj.org/article/da6ce88eaca443b4b36d698e6a2035ef
Autor:
Mehmet A. Bilen, James F. Jiang, Caroline S. Jansen, Jacqueline T. Brown, Lara R. Harik, Aarti Sekhar, Haydn Kissick, Shishir K. Maithel, Omer Kucuk, Bradley Carthon, Viraj A. Master
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
IntroductionCabozantinib (XL-184) is a small molecule inhibitor of the tyrosine kinases c-Met, AXL, and VEGFR2 that has been shown to reduce tumor growth, metastasis, and angiogenesis. After the promising results from the METEOR and CABOSUN trials, c
Externí odkaz:
https://doaj.org/article/9bd82e94fe14462488e08962f8af3568
Autor:
Camilla Margaroli, Maria A. Cardenas, Caroline S. Jansen, Adriana Moon Reyes, Fares Hosseinzadeh, Gordon Hong, Yilin Zhang, Haydn Kissick, Rabindra Tirouvanziam, Viraj A. Master
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Infiltrating tumor neutrophils and myeloid-derived suppressor cells represent major populations in the tumor microenvironment that contribute to tumor progression. However, the phenotype of circulating and tumor-associated neutrophils, and the impact
Externí odkaz:
https://doaj.org/article/5283fdc8f8d9452a9f047350ce83a0a6
Autor:
David J. Einstein, Steven P. Balk, Adam G. Sowalsky, Haydn Kissick, Sabina Signoretti, Huihui Ye, Philip J. Saylor, David B. Sykes, Olga Voznesensky, Anson T. Ku, Ross Lake, Scott Wilkinson, Luke del Balzo, Taghreed Hirz, Caroline S. Jansen, Miriam Ficial, Carla Calagua
Purpose:A subset of primary prostate cancer expresses programmed death-ligand 1 (PD-L1), but whether they have a unique tumor immune microenvironment or genomic features is unclear.Experimental Design:We selected PD-L1–positive high-grade and/or hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36a7b22af536c2e4eaf7236bc4e0e466
https://doi.org/10.1158/1078-0432.c.6530387.v1
https://doi.org/10.1158/1078-0432.c.6530387.v1
Autor:
David J. Einstein, Steven P. Balk, Adam G. Sowalsky, Haydn Kissick, Sabina Signoretti, Huihui Ye, Philip J. Saylor, David B. Sykes, Olga Voznesensky, Anson T. Ku, Ross Lake, Scott Wilkinson, Luke del Balzo, Taghreed Hirz, Caroline S. Jansen, Miriam Ficial, Carla Calagua
Supplementary Data from A Subset of Localized Prostate Cancer Displays an Immunogenic Phenotype Associated with Losses of Key Tumor Suppressor Genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4abfd00712f3fea0f384cc9a84b9731a
https://doi.org/10.1158/1078-0432.22480184.v1
https://doi.org/10.1158/1078-0432.22480184.v1