Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Caroline Roelants"'
Autor:
Alexandre Bancet, Rita Frem, Florian Jeanneret, Angélique Mularoni, Pauline Bazelle, Caroline Roelants, Jean-Guy Delcros, Jean-François Guichou, Catherine Pillet, Isabelle Coste, Toufic Renno, Christophe Battail, Claude Cochet, Thierry Lomberget, Odile Filhol, Isabelle Krimm
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108903- (2024)
Summary: Although the involvement of protein kinase CK2 in cancer is well-documented, there is a need for selective CK2 inhibitors suitable for investigating CK2 specific roles in cancer-related biological pathways and further exploring its therapeut
Externí odkaz:
https://doaj.org/article/41eefb09154c47d1a837761d86fb8080
Autor:
Sofia Giacosa, Catherine Pillet, Irinka Séraudie, Laurent Guyon, Yann Wallez, Caroline Roelants, Christophe Battail, Bertrand Evrard, Frédéric Chalmel, Caroline Barette, Emmanuelle Soleilhac, Marie-Odile Fauvarque, Quentin Franquet, Clément Sarrazin, Nicolas Peilleron, Gaëlle Fiard, Jean-Alexandre Long, Jean-Luc Descotes, Claude Cochet, Odile Filhol
Publikováno v:
Cancers, Vol 13, Iss 3, p 576 (2021)
Kinase-targeted agents demonstrate antitumor activity in advanced metastatic clear cell renal cell carcinoma (ccRCC), which remains largely incurable. Integration of genomic approaches through small-molecules and genetically based high-throughput scr
Externí odkaz:
https://doaj.org/article/a9cddb0170b449938a2e87cf0a411bed
Autor:
Caroline Roelants, Catherine Pillet, Quentin Franquet, Clément Sarrazin, Nicolas Peilleron, Sofia Giacosa, Laurent Guyon, Amina Fontanell, Gaëlle Fiard, Jean-Alexandre Long, Jean-Luc Descotes, Claude Cochet, Odile Filhol
Publikováno v:
Cancers, Vol 12, Iss 1, p 232 (2020)
Clear cell renal cell carcinoma (ccRCC) is the third type of urologic cancer. At time of diagnosis, 30% of cases are metastatic with no effect of chemotherapy or radiotherapy. Current targeted therapies lead to a high rate of relapse and resistance a
Externí odkaz:
https://doaj.org/article/7bcd184554cd41a7a7211abe0599521d
Autor:
Alexandre Bancet, Rita Frem, Florian Jeanneret, Angélique Mularoni, Pauline Bazelle, Caroline Roelants, Jean-Guy Delcros, Jean-François Guichou, Catherine Pillet, Isabelle Coste, Toufic Renno, Christophe Battail, Claude Cochet, Thierry Lomberget, Odile Filhol, Isabelle Krimm
Although the involvement of protein kinase CK2 in cancer is well-documented, there is a need for selective CK2 inhibitors suitable for investigating CK2 specific roles in cancer-related biological pathways and further explore its therapeutic potentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecc80309dd80d08e01af158a30d3d7bc
https://doi.org/10.1101/2022.12.16.520736
https://doi.org/10.1101/2022.12.16.520736
Autor:
Nadia Cherradi, Josiane Denis, Laurent Guyon, Felicitas Rataj, Séverine Planel, Odile Filhol, Jean-Jacques Feige, Caroline Roelants
Publikováno v:
Oncogene
Oncogene, Nature Publishing Group, 2019, ⟨10.1038/s41388-019-0784-8⟩
Oncogene, 2019, ⟨10.1038/s41388-019-0784-8⟩
Oncogene, Nature Publishing Group, 2019, ⟨10.1038/s41388-019-0784-8⟩
Oncogene, 2019, ⟨10.1038/s41388-019-0784-8⟩
International audience; Altered expression of regulatory RNA-binding proteins (RBPs) in cancer leads to abnormal expression of mRNAs encoding many factors involved in cancer hallmarks. While conventional anticancer therapies usually target one pathwa
Autor:
Yann Wallez, Laurent Guyon, Caroline Roelants, Christophe Battail, Q. Franquet, Frédéric Chalmel, Irinka Séraudie, Claude Cochet, Caroline Barette, Odile Filhol, Sofia Giacosa, Nicolas Peilleron, Marie-Odile Fauvarque, Catherine Pillet, Emmanuelle Soleilhac, Clément Sarrazin, Bertrand Evrard, Gaelle Fiard, Jean-Luc Descotes, Jean-Alexandre Long
Publikováno v:
Cancers
Cancers, 2021, 13 (3), pp.576. ⟨10.3390/cancers13030576⟩
Cancers, MDPI, 2021, 13 (3), pp.576. ⟨10.3390/cancers13030576⟩
Volume 13
Issue 3
Cancers, Vol 13, Iss 576, p 576 (2021)
Cancers, 2021, 13 (3), pp.576. ⟨10.3390/cancers13030576⟩
Cancers, MDPI, 2021, 13 (3), pp.576. ⟨10.3390/cancers13030576⟩
Volume 13
Issue 3
Cancers, Vol 13, Iss 576, p 576 (2021)
Simple Summary Renal cell carcinoma (RCC) is the eighth leading malignancy in the world, accounting for 4% of all cancers with poor outcome when metastatic. Protein kinases are highly druggable proteins, which are often aberrantly activated in cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c238a075eb6e95aa7f4ac868a4265e67
https://hal.science/hal-03134709/document
https://hal.science/hal-03134709/document
Autor:
Nihel Berrebeh, Emmanuelle Tillet, Hequn Liu, Christophe Guignabert, Ly Tu, Sabine Bailly, Christophe Battail, Martina Rossi, Nicolas Chaumontel, Marie Ouarné, Laurent Savale, Thomas Daubon, Marc Humbert, Agnès Desroches-Castan, Christine Mallet, Caroline Roelants, Elise Helfer, Claire Bouvard, Pascale Perret, Andreas Bikfalvi
Publikováno v:
Cardiovascular Research
Cardiovascular Research, 2021, ⟨10.1093/cvr/cvab187⟩
Cardiovascular Research, 2021, pp.cvab187. ⟨10.1093/cvr/cvab187⟩
Cardiovascular Research, Oxford University Press (OUP), 2021, ⟨10.1093/cvr/cvab187⟩
Cardiovascular Research, Oxford University Press (OUP), 2021, pp.cvab187. ⟨10.1093/cvr/cvab187⟩
Cardiovascular Research, 2021, ⟨10.1093/cvr/cvab187⟩
Cardiovascular Research, 2021, pp.cvab187. ⟨10.1093/cvr/cvab187⟩
Cardiovascular Research, Oxford University Press (OUP), 2021, ⟨10.1093/cvr/cvab187⟩
Cardiovascular Research, Oxford University Press (OUP), 2021, pp.cvab187. ⟨10.1093/cvr/cvab187⟩
Aims BMP9 and BMP10 mutations were recently identified in patients with pulmonary arterial hypertension, but their specific roles in the pathogenesis of the disease are still unclear. We aimed to study the roles of BMP9 and BMP10 in cardiovascular ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d80d461b345d64ba507813f933802413
https://doi.org/10.1093/cvr/cvab187
https://doi.org/10.1093/cvr/cvab187
Protein kinase CK2 contributes to placental development: physiological and pathological implications
Autor:
Nicolas Lemaitre, Claude Cochet, Daniel Vaiman, Déborah Reynaud, Odile Filhol, Mohamed Benharouga, Nadia Alfaidy, Roland Abi Nahed, Solene Lartigue, Caroline Roelants
Publikováno v:
Journal of Molecular Medicine
Journal of Molecular Medicine, Springer Verlag, 2020, 98 (1), pp.123-133. ⟨10.1007/s00109-019-01855-0⟩
Journal of Molecular Medicine, 2020, 98 (1), pp.123-133. ⟨10.1007/s00109-019-01855-0⟩
Journal of Molecular Medicine, Springer Verlag, 2020, 98 (1), pp.123-133. ⟨10.1007/s00109-019-01855-0⟩
Journal of Molecular Medicine, 2020, 98 (1), pp.123-133. ⟨10.1007/s00109-019-01855-0⟩
International audience; Preeclampsia (PE) is the most threatening pathology of human pregnancy. Its development is thought to be due to a failure in the invasion of trophoblast cells that establish the feto-maternal circulation. Protein kinase CK2 is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::384959d647d07304f1114e51f8f6a61c
https://hal.archives-ouvertes.fr/hal-02456988
https://hal.archives-ouvertes.fr/hal-02456988
Autor:
Andreas Christ, Aldo Leal-Egaña, Timothée Vignaud, Caroline Roelants, Gaëlle Letort, Manuel Théry, Odile Filhol, Jean Louis Martiel
Publikováno v:
Molecular Biology of the Cell
Molecular Biology of the Cell, American Society for Cell Biology, 2017, 28 (12), pp.1612-1621
Molecular Biology of the Cell, American Society for Cell Biology, 2017, 28 (12), pp.1612-1621. ⟨10.1091/mbc.e16-10-0694⟩
Molecular Biology of the Cell, American Society for Cell Biology, 2017, 28 (12), pp.1612-1621. ⟨10.1091/mbc.E16-10-0694⟩
Molecular Biology of the Cell, 2017, 28 (12), pp.1612-1621. ⟨10.1091/mbc.E16-10-0694⟩
Molecular Biology of the Cell, American Society for Cell Biology, 2017, 28 (12), pp.1612-1621
Molecular Biology of the Cell, American Society for Cell Biology, 2017, 28 (12), pp.1612-1621. ⟨10.1091/mbc.e16-10-0694⟩
Molecular Biology of the Cell, American Society for Cell Biology, 2017, 28 (12), pp.1612-1621. ⟨10.1091/mbc.E16-10-0694⟩
Molecular Biology of the Cell, 2017, 28 (12), pp.1612-1621. ⟨10.1091/mbc.E16-10-0694⟩
Normal and transformed motile cells follow a common trend in which size and contractile forces are negatively correlated with cell speed. However, tumorigenic factors amplify the preexisting population heterogeneity and lead some cells to exhibit bio
Autor:
Carl Mann, Raphael Guerois, May Bakail, Ekaterina Boyarchuk, Albane Gaubert, Marie-Cécile Gaillard, Zachary A. Gurard-Levin, Françoise Ochsenbein, Brice Murciano, Claire Frederic, Gwenaëlle Moal, Geneviève Almouzni, Jean-Yves Thuret, Régis Courbeyrette, Morgane Agez, Marie-Hélène Le Du, Nicolas Richet, Jessica Andreani, Adeline Poitou, Nadia Cherradi, Berengère Guichard, Guillaume Pinna, Caroline Roelants
Publikováno v:
Cell Chemical Biology
Cell Chemical Biology, 2019, ⟨10.1016/j.chembiol.2019.09.002⟩
Cell Chemical Biology, Cell Press, 2019, 26 (11), pp.1573-1585.e10. ⟨10.1016/j.chembiol.2019.09.002⟩
Cell Chemical Biology, 2019, 26 (11), pp.1573-1585.e10. ⟨10.1016/j.chembiol.2019.09.002⟩
Cell Chemical Biology, 2019, ⟨10.1016/j.chembiol.2019.09.002⟩
Cell Chemical Biology, Cell Press, 2019, 26 (11), pp.1573-1585.e10. ⟨10.1016/j.chembiol.2019.09.002⟩
Cell Chemical Biology, 2019, 26 (11), pp.1573-1585.e10. ⟨10.1016/j.chembiol.2019.09.002⟩
International audience; Anti-silencing function 1 (ASF1) is a conserved H3-H4 histone chaperone involved in histone dynamics during replication, transcription, and DNA repair. Overexpressed in proliferating tissues including many tumors, ASF1 has eme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e363462fa67802e4c07a173d447801b2
https://hal.archives-ouvertes.fr/hal-02301617
https://hal.archives-ouvertes.fr/hal-02301617