Lack of Hypothalamus Polysialylation Inducibility Correlates With Maladaptive Eating Behaviors and Predisposition to Obesity

Autor: Xavier Brenachot, Emmanuelle Nédélec, Selma Ben Fradj, Gaelle Boudry, Véronique Douard, Amélie Laderrière, Aleth Lemoine, Fabienne Liénard, Danaé Nuzzaci, Luc Pénicaud, Caroline Rigault, Alexandre Benani

Publikováno v: Frontiers in Nutrition, Vol 5 (2018)

High variability exists in individual susceptibility to develop overweight in an obesogenic environment and the biological underpinnings of this heterogeneity are poorly understood. In this brief report, we show in mice that the vulnerability to diet

Externí odkaz: https://doaj.org/article/339fc6dabc1c428faed4cf1c5ddd70f1

Cerebral cell renewal in adult mice controls the onset of obesity.

Autor: Alexandra Gouazé, Xavier Brenachot, Caroline Rigault, Alice Krezymon, Camille Rauch, Emmanuelle Nédélec, Aleth Lemoine, Jean Gascuel, Sylvian Bauer, Luc Pénicaud, Alexandre Benani

Publikováno v: PLoS ONE, Vol 8, Iss 8, p e72029 (2013)

The hypothalamus plays a crucial role in the control of the energy balance and also retains neurogenic potential into adulthood. Recent studies have reported the severe alteration of the cell turn-over in the hypothalamus of obese animals and it has

Externí odkaz: https://doaj.org/article/cf5798e030f4437394f7b991468be247

Détection cérébrale du glucose, plasticité neuronale et métabolisme énergétique

Autor: Alexandre Benani, Lionel Carneiro, C. Leloup, Xavier Fioramonti, Luc Pénicaud, Alexandra Gouazé, Chloé Chrétien, Caroline Rigault, Xavier Brenachot

Publikováno v: Cahiers de Nutrition et de Diététique. 52:19-25

Resume L’apport d’energie est, dans la plupart des cas extremement, bien controle et est ajuste aux depenses d’energie d’un individu donne, c’est ce que l’on nomme l’homeostasie energetique. Cet equilibre repose en grande partie sur la

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dfd1800925187dee715810d969ea983b
https://doi.org/10.1016/j.cnd.2016.09.006

Brain Control of Plasma Cholesterol Involves Polysialic Acid Molecules in the Hypothalamus

Autor: Danaé Nuzzaci, Aleth Lemoine, Xavier Brenachot, Caroline Rigault, Thomas Gautier, Laurent Lagrost, Luc Penicaud, Emmanuelle Nédélec, Valérie Deckert, Amélie Laderrière, Alexandre Benani

Publikováno v: Frontiers in Neuroscience
Frontiers in Neuroscience, Frontiers, 2017, 11, pp.245. ⟨10.3389/fnins.2017.00245⟩
Frontiers in Neuroscience, Frontiers, 2017, 11, pp.245. 〈http://journal.frontiersin.org/article/10.3389/fnins.2017.00245/full〉. 〈10.3389/fnins.2017.00245〉
Frontiers in Neuroscience, 2017, 11, pp.245. ⟨10.3389/fnins.2017.00245⟩
Frontiers in Neuroscience (11), 245. (2017)
Frontiers in Neuroscience, Vol 11 (2017)

IF 3.566; International audience; The polysialic acid (PSA) is a large glycan that is added to cell-surface proteins during their post-translational maturation. In the brain, PSA modulates distances between cells and controls the plasticity of the ne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64901789b2b362751934443b6f22bc8a
http://europepmc.org/articles/PMC5414510

L-Carnitine Supplementation and Physical Exercise Restore Age-Associated Decline in Some Mitochondrial Functions in the Rat

Autor: Caroline Rigault, Jean Demarquoy, Frédéric Mazué, Arnaud Bernard, Françoise Le Borgne

Publikováno v: The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. 63:1027-1033

In mammals, during the aging process, an atrophy of the muscle fibers, an increase in body fat mass, and a decrease in skeletal muscle oxidative capacities occur. Compounds and activities that interact with lipid oxidative metabolism may be useful in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d450b3ded4cb1a872d31c48a18d1fe29
https://doi.org/10.1093/gerona/63.10.1027