Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Caroline Remouchamps"'
Autor:
Suzanne Faure-Dupuy, Tobias Riedl, Maude Rolland, Zoheir Hizir, Florian Reisinger, Katharina Neuhaus, Svenja Schuehle, Caroline Remouchamps, Nicolas Gillet, Maximilian Schönung, Mira Stadler, Jochen Wettengel, Romain Barnault, Romain Parent, Linda Christina Schuster, Rayan Farhat, Sandra Prokosch, Corinna Leuchtenberger, Rupert Öllinger, Thomas Engleitner, Karsten Rippe, Roland Rad, Kristian Unger, Darjus Tscharahganeh, Daniel B. Lipka, Ulrike Protzer, David Durantel, Julie Lucifora, Emmanuel Dejardin, Mathias Heikenwälder
Publikováno v:
JHEP Reports, Vol 3, Iss 6, Pp 100354- (2021)
Background & Aims: Immune-mediated induction of cytidine deaminase APOBEC3B (A3B) expression leads to HBV covalently closed circular DNA (cccDNA) decay. Here, we aimed to decipher the signalling pathway(s) and regulatory mechanism(s) involved in A3B
Externí odkaz:
https://doaj.org/article/f8e8591deea845fbbd851f975b52e574
Autor:
Peter Vandenabeele, Sandrine Marchetti, Jorge Caamano, F. Mair, Jacques Piette, Caroline Remouchamps, Cécile Bénézech, Layla Boutaffala, Mathias Heikenwalder, Mathieu J.M. Bertrand, Florian Reisinger, Jean-Ehrland Ricci, A. Hupalowska, Gitta Maria Seleznik, Marianne K. Janas, M. T. Fernandes, Emmanuel Dejardin, Corinne Ganeff, Burkhard Becher, Percy A. Knolle
Publikováno v:
Cell Death Differ. 22, 2020-2033 (2015)
Cell death and differentiation
Cell death and differentiation
NF-κB-inducing kinase (NIK) is well-known for its role in promoting p100/NF-κB2 processing into p52, a process defined as the alternative, or non-canonical, NF-κB pathway. Here we reveal an unexpected new role of NIK in TNFR1-mediated RIP1-depende
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8eca7c065b0fc4d9e0112acaf23025a
https://doi.org/10.1038/cdd.2015.69
https://doi.org/10.1038/cdd.2015.69
Autor:
Cécile Bénézech, Jacques Piette, Alain Chariot, Layla Boutaffala, Géraldine Galopin, Sarah Vandepaer, Pascal Schneider, Emmanuel Dejardin, Sandra Ormenese, Jorge Caamano, Caroline Remouchamps, Fabrice Bouillenne, Corinne Ganeff
Publikováno v:
Ganeff, C, Remouchamps, C, Boutaffala, L, Benezech, C, Galopin, G, Vandepaer, S, Bouillenne, F, Ormenese, S, Chariot, A, Schneider, P, Caamaño, J, Piette, J & Dejardin, E 2011, ' Induction of the alternative NF-κB pathway by lymphotoxin αβ (LTαβ) relies on internalization of LTβ receptor ', Molecular and Cellular Biology, vol. 31, no. 21, pp. 4319-34 . https://doi.org/10.1128/MCB.05033-11
Several tumor necrosis factor receptor (TNFR) family members activate both the classical and the alternative NF-κB pathways. However, how a single receptor engages these two distinct pathways is still poorly understood. Using lymphotoxin β receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dae5706ee8f91f0a0e4575505eeb54a1
https://doi.org/10.1128/mcb.05033-11
https://doi.org/10.1128/mcb.05033-11
Publikováno v:
Cytokine & Growth Factor Reviews. 22:301-310
This review focuses on the biological functions and signalling pathways activated by Lymphotoxin α (LTα)/Lymphotoxin β (LTβ) and their receptor LTβR. Genetic mouse models shed light on crucial roles for LT/LTβR to build and to maintain the arch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56ab0a9774cb85bad5a940d02918a0db
https://doi.org/10.1016/j.cytogfr.2011.11.007
https://doi.org/10.1016/j.cytogfr.2011.11.007
Autor:
Caroline Remouchamps, Jérémie Mortier, Bernard Masereel, Raphaël Frédérick, Corinne Ganeff, Jacques Piette
Publikováno v:
Bioorganic and medicinal chemistry letters. 20(15):4515-4520
As a wide variety of pro-inflammatory cytokines are involved in the development of rheumatoid arthritis (RA), there is an urgent need for the discovery of novel therapeutic strategies. Among these, the inhibition of the NF-κB inducing kinase (NIK),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9ef042209fe13a2f41fc5a3dca25672
https://researchportal.unamur.be/en/publications/835fee48-35c7-4395-a36b-c6e9f1a0f2cd
https://researchportal.unamur.be/en/publications/835fee48-35c7-4395-a36b-c6e9f1a0f2cd
Autor:
Patrice Talaga, Raphaël Frédérick, Jacques Piette, Bernard Masereel, Jérémie Mortier, Caroline Remouchamps, Emmanuel Dejardin, Lionel Pochet, Johan Wouters, Corinne Ganeff
Publikováno v:
Biochemical Pharmacology. 79:1462-1472
In this work, we aimed to build a 3D-model of NIK and to study the binding of pyrazolo[4,3-c]isoquinolines with a view to highlight the structural elements responsible for their inhibitory potency. However, in the course of this work, we unexpectedly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c567e3352f0afdd0e843be867673ed9e
https://doi.org/10.1016/j.bcp.2010.01.007
https://doi.org/10.1016/j.bcp.2010.01.007
Autor:
Vincent Bours, Alain Chariot, Sébastien Tabruyn, Catherine Verhaeghe, Benoit Hennuy, Alain Vanderplasschen, Cécile Oury, Caroline Remouchamps
Publikováno v:
Biochemical Pharmacology. 73:1982-1994
In cystic fibrosis (CF) patients, pulmonary inflammation is a major cause of morbidity and mortality and may precede bacterial colonization. The aim of the present study was to investigate the molecular mechanisms underlying intrinsic inflammation in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abcd7a19062d03f9b7dad28c5723e548
https://doi.org/10.1016/j.bcp.2007.03.019
https://doi.org/10.1016/j.bcp.2007.03.019
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1280
The alternative or noncanonical NF-κB pathway regulates the generation of p52-containing NF-κB dimers (e.g., p52/RelB) through a partial degradation (called processing) of the precursor p100 into p52. This pathway is activated by a subset of non-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2999dad60eca62013cdc08b1cfbbd193
https://pubmed.ncbi.nlm.nih.gov/25736746
https://pubmed.ncbi.nlm.nih.gov/25736746
Publikováno v:
Methods in Molecular Biology ISBN: 9781493924219
The alternative or noncanonical NF-κB pathway regulates the generation of p52-containing NF-κB dimers (e.g., p52/RelB) through a partial degradation (called processing) of the precursor p100 into p52. This pathway is activated by a subset of non-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52026320c3c4894bec8f43ffec384377
https://doi.org/10.1007/978-1-4939-2422-6_7
https://doi.org/10.1007/978-1-4939-2422-6_7
Autor:
Michael Schindler, Wen Min Chou, Florian Reisinger, Ulrike Protzer, Yuchen Xia, T. Jake Liang, Daniela Stadler, Zuzanna Makowska, Markus H. Heim, Norbert Hüser, David Durantel, Tassilo Volz, Caroline Remouchamps, Carsten Münk, Emmanuel Dejardin, Maura Dandri, Herwig Koppensteiner, Mathias Heikenwalder, Ke Zhang, Jeffrey L. Browning, Martin F. Sprinzl, Julie Lucifora, Xiaoming Cheng, Wolfgang E. Thasler
Publikováno v:
Science
Science, American Association for the Advancement of Science, 2014, 343 (6176), pp.1221-1228. ⟨10.1126/science.1243462⟩
Science, American Association for the Advancement of Science, 2014, 343 (6176), pp.1221-1228. ⟨10.1126/science.1243462⟩
Clearance of Chronic Virus The family of mRNA-editing enzymes, APOBEC, restricts hepatitis B virus (HBV) replication. Lucifora et al. (p. 1221 , published online 20 February; see the Perspective by Shlomai and Rice ) provide evidence that specific AP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::593caf19686ebb19352147591001e740
https://hal.archives-ouvertes.fr/hal-03315632/document
https://hal.archives-ouvertes.fr/hal-03315632/document