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pro vyhledávání: '"Caroline Rönnlund"'
Autor:
Caroline Rönnlund, Emmanouil G. Sifakis, Caroline Schagerholm, Qiao Yang, Emelie Karlsson, Xinsong Chen, Theodoros Foukakis, Jodi Weidler, Michael Bates, Irma Fredriksson, Stephanie Robertson, Johan Hartman
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-13 (2024)
Abstract Background Overexpression of human epidermal growth factor receptor 2 (HER2) caused by HER2 gene amplification is a driver in breast cancer tumorigenesis. We aimed to investigate the prognostic significance of manual scoring and digital imag
Externí odkaz:
https://doaj.org/article/45539500ca624cfc9e0f07721e2b11cd
Autor:
Balazs Acs, Irma Fredriksson, Caroline Rönnlund, Catharina Hagerling, Anna Ehinger, Anikó Kovács, Rasmus Røge, Jonas Bergh, Johan Hartman
Publikováno v:
Cancers, Vol 13, Iss 5, p 1166 (2021)
We compared estrogen receptor (ER), progesterone receptor (PR), human epidermal growth-factor receptor 2 (HER2), Ki67, and grade scores among the pathology departments in Sweden. We investigated how ER and HER2 positivity rates affect the distributio
Externí odkaz:
https://doaj.org/article/de326149510c45c6b334362f92a824d6
Publikováno v:
Cancer Research. 82:P1-02
Background: Around 15% of all breast cancers are HER2+, a subtype that prior to HER2-targeted therapy was associated with a poor prognosis. With advances in treatment the survival has dramatically improved, and previous studies suggest that the level
Publikováno v:
Breast Cancer Research and Treatment. 174:795-805
The accuracy of predictive and prognostic biomarker assessment in breast cancer is paramount since these guide therapy decisions. The aim was to investigate the concordance of biomarkers and immunohistochemical (IHC)-based surrogate tumor subtypes be
Autor:
Anders Ström, Justin D. Crofts, Patrick Müller, Kenneth W. Merrell, Caroline Rönnlund, Jan-Åke Gustafsson, Chin-Yo Lin
Publikováno v:
Journal of Endocrinology. 200:311-319
Regulation of hairy and enhancer of split homologue-1 (HES-1) by estradiol and all-trans retinoic acid affects proliferation of human breast cancer cells. Here, we identify and characterize cis-regulatory elements involved in HES-1 regulation. In the