Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Caroline Patriarca"'
Publikováno v:
Toxicology. 119:51-58
A number of drugs and chemicals can induce autoimmune disorders. The use of autoantibody assays in toxicology has been evaluated as a tool to predict and explain autoimmune reactions. Autoantibodies are divided between organ-specific and ubiquitous a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89d0e32999a32cc121719c9821ca192d
https://doi.org/10.1016/s0300-483x(96)03596-2
https://doi.org/10.1016/s0300-483x(96)03596-2
Publikováno v:
Toxicology. 119:45-49
The popliteal lymph node (PLN) assay is based on the assumption that a mechanism similar to a graft-versus-host (GvH) reaction is involved in 'GvH-like' drug-induced side-effects, including generalized lymphadenopathy, serum sickness-like disease, sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a954610340f5fbdc1fed5fb09fecdd07
https://doi.org/10.1016/s0300-483x(96)03595-0
https://doi.org/10.1016/s0300-483x(96)03595-0
Publikováno v:
International Journal of Immunopharmacology. 17:813-819
Serotonin (5-HT) has been shown to exert various immunomodulatory effects. In this study, the effects of 5-HT, 5-hydroxy-DL-tryptophan (5-HTP) and dl- p -chlorophenylalanine (PCPA) on the chemiluminescence (CL) responses of rat peripheral blood leuco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d52bf9be6a7c609f7542a9585a41955
https://doi.org/10.1016/0192-0561(95)00071-9
https://doi.org/10.1016/0192-0561(95)00071-9
Publikováno v:
Human & Experimental Toxicology. 13:455-460
Outbred (namely Wistar and Sprague-Dawley) and inbred (Wistar-Furth, Lewis, Fisher 344 and Brown-Norway) strains of rats were screened for their responses to reference compounds in the popliteal lymph node (PLN) assay. Streptozotocin and diphenylhyda
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2d74fad0e61737f7e090544a0c9b004
https://doi.org/10.1177/096032719401300701
https://doi.org/10.1177/096032719401300701
Publikováno v:
Journal of Toxicology and Environmental Health. 41:95-108
The popliteal lymph node (PLN) assay has been proposed as a tool to predict in rodents those xenobiotics likely to induce autoimmune reactions in humans. To further validate this assay and to study the mechanisms involved, histologic changes in PLNs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a832f0b16b4ab8779ca987bdde5f2b09
https://doi.org/10.1080/15287399409531829
https://doi.org/10.1080/15287399409531829
Publikováno v:
Toxicology Letters. 66:21-28
The popliteal lymph node assay (PLNA) was proposed for the preclinical prediction of xenobiotics-induced autoimmune reactions in humans. Among the substances so far tested in this model, procainamide and isoniazid gave negative PLNA responses despite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::329b8d483d58416812e519ec2bd17242
https://doi.org/10.1016/0378-4274(93)90075-9
https://doi.org/10.1016/0378-4274(93)90075-9
Autor:
Geneviève Panaye, Caroline Patriarca, Jacques Descotes, F. Verdier, Jean-Pierre Revillard, Jean-Philippe Brouland, Krzysztof Krzystyniak
Publikováno v:
Journal of Autoimmunity. 5:183-197
Time-related and dose-related popliteal lymph node (PLN) enlargement and lymphocyte subset alterations owing to subcutaneous (s.c.) injection of streptozotocin (STZ) into the foot pad were determined in ( C57BL 6 × DBA 2 )F1 [B6D2F1] mice. Early cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c2c51a9e7a7c9fae2938cf2542f5d53
https://doi.org/10.1016/0896-8411(92)90199-z
https://doi.org/10.1016/0896-8411(92)90199-z