Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Caroline P. Kerr"'
Autor:
Ying Zhang, Raghava N. Sriramaneni, Paul A. Clark, Justin C. Jagodinsky, Mingzhou Ye, Wonjong Jin, Yuyuan Wang, Amber Bates, Caroline P. Kerr, Trang Le, Raad Allawi, Xiuxiu Wang, Ruosen Xie, Thomas C. Havighurst, Ishan Chakravarty, Alexander L. Rakhmilevich, Kathleen A. O’Leary, Linda A. Schuler, Paul M. Sondel, Kyungmann Kim, Shaoqin Gong, Zachary S. Morris
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Radiotherapy can activate an in situ vaccine response and promote response to immune checkpoint inhibitors. Here the authors design a multifunctional nanoparticle to enhance tumor antigen presentation and modulate the tumor immune microenvironment fo
Externí odkaz:
https://doaj.org/article/5182a8b990d848bdaa69308ac2077051
Autor:
Caroline P. Kerr, Joseph J. Grudzinski, Thanh Phuong Nguyen, Reinier Hernandez, Jamey P. Weichert, Zachary S. Morris
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 128 (2022)
Targeted radionuclide therapy (TRT) and immunotherapy are rapidly growing classes of cancer treatments. Basic, translational, and clinical research are now investigating therapeutic combinations of these agents. In comparison to external beam radiati
Externí odkaz:
https://doaj.org/article/03b157f0bf9b43879e7cd003d2a058cd
Autor:
Ying Zhang, Md Mahfuzur Rahman, Paul A. Clark, Raghava N. Sriramaneni, Thomas Havighurst, Caroline P. Kerr, Min Zhu, Jamie Jones, Xiuxiu Wang, KyungMann Kim, Shaoqin Gong, Zachary S. Morris
Publikováno v:
ACS Nano.
Autor:
Thanh Phuong T. Nguyen, Caroline P. Kerr, Joseph J. Grudzinski, Carolina A. Ferreira, Julia Sheehan-Klenk, Ohyun Kwon, Maria Powers, Paul A. Clark, Raghava N. Sriramaneni, Reinier Hernandez, Bryan Bednarz, Jamey P. Weichert, Zachary S. Morris
Publikováno v:
Cancer Research. 83:6407-6407
Background: Targeted radionuclide therapy (TRT) delivers radiation treatment systemically to tumor sites via a therapeutic radionuclide-linked tumor-selective targeting vector. NM600 is an alkylphosphocholine analog selectively taken up and retained
Autor:
Caroline P. Kerr, Joseph J. Grudzinski, Carolina A. Ferreira, David Adam, Julia Sheehan-Klenk, Amber M. Bates, Won Jong Jin, Ohyun Kwon, Justin C. Jagodinsky, Maria Powers, Raghava N. Sriramaneni, Paul A. Clark, Luke Zangl, Thanh Phuong T. Nguyen, Anatoly N. Pinchuk, Cynthia Choi, Christopher F. Massey, Reinier Hernandez, Bryan Bednarz, Jamey P. Weichert, Zachary S. Morris
Publikováno v:
Cancer Research. 83:2828-2828
Background: Sequencing of immune checkpoint inhibitors (ICI) and external beam radiation therapy (EBRT) for cancer treatment has been studied, but the optimal sequencing has yet to be determined. While some studies have noted therapeutic advantages o
Autor:
Ryan M Kempster, Channing A Egeberg, Nathan S Hart, Laura Ryan, Lucille Chapuis, Caroline C Kerr, Carl Schmidt, Charlie Huveneers, Enrico Gennari, Kara E Yopak, Jessica J Meeuwig, Shaun P Collin
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0157717 (2016)
Sharks play a vital role in the health of marine ecosystems, but the potential threat that sharks pose to humans is a reminder of our vulnerability when entering the ocean. Personal shark deterrents are being marketed as the solution to mitigate the
Externí odkaz:
https://doaj.org/article/9964ae48c85a4abd8c493c6ad2bf4752
Autor:
Ying Zhang, Raghava N. Sriramaneni, Paul A. Clark, Justin C. Jagodinsky, Mingzhou Ye, Wonjong Jin, Yuyuan Wang, Amber Bates, Caroline P. Kerr, Trang Le, Raad Allawi, Xiuxiu Wang, Ruosen Xie, Thomas C. Havighurst, Ishan Chakravarty, Alexander L. Rakhmilevich, Kathleen A. O’Leary, Linda A. Schuler, Paul M. Sondel, Kyungmann Kim, Shaoqin Gong, Zachary S. Morris
Publikováno v:
Nature communications. 13(1)
Radiation therapy (RT) activates an in situ vaccine effect when combined with immune checkpoint blockade (ICB), yet this effect may be limited because RT does not fully optimize tumor antigen presentation or fully overcome suppressive mechanisms in t
Autor:
Caroline P. Kerr, Amber M. Bates, Joseph J. Grudzinski, Carolina A. Ferreira, Julia Sheehan-Klenk, David Adam, Maria Powers, Wonjong Jin, Justin C. Jagodinsky, Raghava N. Sriramaneni, Paul A. Clark, Luke Zangl, Anatoly N. Pinchuk, Alejandro J. Onate, Ria Kumari, Cynthia Choi, Christopher F. Massey, Bryan Bednarz, Reinier Hernandez, Jamey P. Weichert, Zachary S. Morris
Publikováno v:
Cancer Research. 82:1306-1306
Purpose: In preclinical studies, we have demonstrated that delivering low dose radiation to all tumor sites utilizing 90Y-NM600 improves the response to immune checkpoint inhibitors (ICIs). NM600 is an alkylphosphocholine analog that is selectively t
Autor:
Matt C. Mannino, Caroline P. Kerr, Jennifer L. Schehr, Shuang G. Zhao, Zachary S. Morris, Joshua M. Lang
Publikováno v:
Cancer Research. 82:5121-5121
Head and Neck Cancer (HNC) is an aggressive disease, often treated with combinations of radiation, targeted therapy and immunotherapies. Immune checkpoint inhibitors for patients with HNC have shown modest clinical response rates of ~20%. It is uncle
Autor:
David J Midgley, Paul Greenfield, Janet M Shaw, Yalchin Oytam, Dongmei Li, Caroline A Kerr, Philip Hendry
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33875 (2012)
The second generation (G2) PhyloChip is designed to detect over 8700 bacteria and archaeal and has been used over 50 publications and conference presentations. Many of those publications reveal that the PhyloChip measures of species richness greatly
Externí odkaz:
https://doaj.org/article/54b2624ae7a54ea787fe0453c5900a60