Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Caroline O. Tabler"'
Publikováno v:
Viruses, Vol 16, Iss 6, p 849 (2024)
HIV-1 protease inhibitors are an essential component of antiretroviral therapy. However, drug resistance is a pervasive issue motivating a persistent search for novel therapies. Recent reports found that when protease activates within the host cell
Externí odkaz:
https://doaj.org/article/6b09d0fae161449aa01aeacdcbf35469
Autor:
Caroline O. Tabler, John C. Tilton
Publikováno v:
Viruses, Vol 16, Iss 5, p 802 (2024)
This review focuses on the emerging field of flow virometry, the study and characterization of individual viral particles using flow cytometry instruments and protocols optimized for the detection of nanoscale events. Flow virometry faces considerabl
Externí odkaz:
https://doaj.org/article/10026c5dfb89411e901cc9775490377c
Autor:
Zach Troyer, Najwa Alhusaini, Caroline O. Tabler, Thomas Sweet, Karina Inacio Ladislau deCarvalho, Daniela M. Schlatzer, Lenore Carias, Christopher L. King, Kenneth Matreyek, John C. Tilton
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 8, Pp n/a-n/a (2021)
Abstract In late 2019, a novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) emerged in Wuhan, China. SARS‐CoV‐2 and the disease it causes, coronavirus disease 2019 (COVID‐19), spread rapidly and became a gl
Externí odkaz:
https://doaj.org/article/0e886399a84546a9b38cb6d6eacdab1d
Autor:
Danica D. Wiredja, Caroline O. Tabler, Daniela M. Schlatzer, Ming Li, Mark R. Chance, John C. Tilton
Publikováno v:
Retrovirology, Vol 15, Iss 1, Pp 1-13 (2018)
Abstract Background Viral reprogramming of host cells enhances replication and is initiated by viral interaction with the cell surface. Upon human immunodeficiency virus (HIV) binding to CD4+ T cells, a signal transduction cascade is initiated that r
Externí odkaz:
https://doaj.org/article/6084940092b8472e83a9ecc95a8d5774
Publikováno v:
J Virol
HIV-1 encodes a viral protease that is essential for the maturation of infectious viral particles. While protease inhibitors are effective antiretroviral agents, recent studies have shown that prematurely activating, rather than inhibiting, protease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::246c95c2f320274d75508380eb4b32ea
https://europepmc.org/articles/PMC9093094/
https://europepmc.org/articles/PMC9093094/
Autor:
Miguel E. Quiñones-Mateu, Lauren E Lapointe, Samira Joussef-Piña, Michał M. Bonar, John C. Tilton, Jake A Galiatsos, Aiman A. Haqqani, Caroline O. Tabler
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
HIV encodes an aspartyl protease that is activated during, or shortly after, budding of viral particles from the surface of infected cells. Protease-mediated cleavage of viral polyproteins is essential to generating infectious viruses, a process know
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5f47d77af301ab8888162315591f9a5
http://link.springer.com/article/10.1038/s41598-020-75118-1
http://link.springer.com/article/10.1038/s41598-020-75118-1
Autor:
Daniela Schlatzer, Caroline O. Tabler, Ming Li, Mark R. Chance, John C. Tilton, Danica Wiredja
Publikováno v:
Retrovirology
Retrovirology, Vol 15, Iss 1, Pp 1-13 (2018)
Retrovirology, Vol 15, Iss 1, Pp 1-13 (2018)
Background Viral reprogramming of host cells enhances replication and is initiated by viral interaction with the cell surface. Upon human immunodeficiency virus (HIV) binding to CD4+ T cells, a signal transduction cascade is initiated that reorganize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::263b9a49a6aacf057a521e1b435cd44b
https://pubmed.ncbi.nlm.nih.gov/29970186
https://pubmed.ncbi.nlm.nih.gov/29970186
Autor:
John C. Tilton, Mark B. Lucera, Carisa A. Tilton, Samantha L. Marek, Caroline O. Tabler, Aiman A. Haqqani
Publikováno v:
Journal of Virological Methods. 195:164-169
Fusion between the viral membrane of human immunodeficiency virus (HIV) and the host cell marks the end of the HIV entry process and the beginning of a series of post-entry events including uncoating, reverse transcription, integration, and viral gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48233f775814d7877d015ed90cf9419d
https://doi.org/10.1016/j.jviromet.2013.08.029
https://doi.org/10.1016/j.jviromet.2013.08.029
Autor:
Hongxia Mao, Aiman A. Haqqani, Jonathan Karn, Curtis Dobrowolski, Caroline O. Tabler, Carisa A. Tilton, John C. Tilton, Mark B. Lucera
Latently infected cells remain a primary barrier to eradication of HIV-1. Over the past decade, a better understanding of the molecular mechanisms by which latency is established and maintained has led to the discovery of a number of compounds that s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::229ce6b5b0eb45a7888dd94d39f7be10
https://europepmc.org/articles/PMC4178860/
https://europepmc.org/articles/PMC4178860/
Autor:
David McDonald, Mark Connors, Aiman A. Haqqani, Caroline O. Tabler, John C. Tilton, Mark B. Lucera, Stephen A. Migueles
CD4 + and CD8 + memory T cells with stem cell-like properties (T SCM cells) have been identified in mice, humans, and nonhuman primates and are being investigated for antitumor and antiviral vaccines and immunotherapies. Whether CD4 + T SCM cells are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5ca598a4a54c2bd1ed622587d89856
https://europepmc.org/articles/PMC3993838/
https://europepmc.org/articles/PMC3993838/