Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Caroline Norez"'
Autor:
Romain Ferru-Clément, Fleur Fresquet, Caroline Norez, Thierry Métayé, Frédéric Becq, Alain Kitzis, Vincent Thoreau
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118943 (2015)
Cystic fibrosis transmembrane conductance regulator (CFTR) is a chloride channel that is expressed on the apical plasma membrane (PM) of epithelial cells. The most common deleterious allele encodes a trafficking-defective mutant protein undergoing en
Externí odkaz:
https://doaj.org/article/06e6a49239cf4287802be970c672be44
Autor:
Laurie-Anne Payet, Linette Kadri, Sébastien Giraud, Caroline Norez, Jean Marc Berjeaud, Christophe Jayle, Sandra Mirval, Frédéric Becq, Clarisse Vandebrouck, Thierry Ferreira
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89044 (2014)
The F508del-CFTR mutation, responsible for Cystic Fibrosis (CF), leads to the retention of the protein in the endoplasmic reticulum (ER). The mistrafficking of this mutant form can be corrected by pharmacological chaperones, but these molecules showe
Externí odkaz:
https://doaj.org/article/143433953bb645d0a8948d6413be1f71
Autor:
Nathalie Benz, Sophie Le Hir, Caroline Norez, Mathieu Kerbiriou, Marie-Laure Calvez, Frédéric Becq, Pascal Trouvé, Claude Férec
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88964 (2014)
Cystic fibrosis (CF), the most common autosomal recessive disease in Caucasians, is due to mutations in the CFTR gene. F508del, the most frequent mutation in patients, impairs CFTR protein folding and biosynthesis. The F508del-CFTR protein is retaine
Externí odkaz:
https://doaj.org/article/0f21a5b6c9dd4b798c1bda4a2a714f44
Autor:
Philippe Compain, Joanna Wencel-Delord, Eugénie Laigre, Caroline Norez, Damien Hazelard, Khadidja Sidelarbi, Raphaël Hensienne, Frédéric Becq, Pierre-Antoine Nocquet
Publikováno v:
Organic and Biomolecular Chemistry
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2016, 14 (9), pp.2780-2796. ⟨10.1039/C5OB02602D⟩
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2016, 14 (9), pp.2780-2796. ⟨10.1039/C5OB02602D⟩
A synthetic route to a new class of conformationally constrained iminosugars based on a 5-azaspiro[3.4]octane skeleton has been developed by way of Rh(ii)-catalyzed C(sp(3))-H amination. The pivotal stereocontrolled formation of the quaternary C-N bo
Autor:
Ariestya Indah Permata Sari, Marie-Claude Pasquet, Alain Kitzis, Véronique Ladeveze, Raed Farhat, Ayman El-Seedy, Frédéric Becq, Caroline Norez
Publikováno v:
Comptes Rendus Biologies
Comptes Rendus Biologies, Elsevier, 2017, 340 (8), pp.367-371. ⟨10.1016/j.crvi.2017.06.001⟩
Comptes Rendus Biologies, Elsevier, 2017, 340 (8), pp.367-371. ⟨10.1016/j.crvi.2017.06.001⟩
Cystic fibrosis is caused by mutations on the Cystic Fibrosis Transmembrane conductance Regulator gene (CFTR). Exonic mutations may have variable effect on the CFTR protein and may alter the normal localization of CFTR on the apical membrane of epith
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::318177a3fcb6d30fc2ba6501cec009a7
https://hal.archives-ouvertes.fr/hal-01708268
https://hal.archives-ouvertes.fr/hal-01708268
Autor:
Véronique Ladeveze, Hugo Talbot, Alain Kitzis, Ayman El-Seedy, Catherine Adolphe, Marie-Claude Pasquet, Caroline Norez, Raí«d Farhat
Publikováno v:
Cellular and molecular biology (Noisy-le-Grand, France). 63(11)
Cystic Fibrosis is the most common recessive autosomal rare disease found in Caucasian. It is caused by mutations on the Cystic Fibrosis Transmembrane Conductance Regulator gene (CFTR) that encodes for a protein located on the apical membrane of epit
Autor:
Maud Frieden, Florentin Huguet, Paul Buscaglia, Pascal Trouvé, Olivier Mignen, Fabrice Antigny, Caroline Norez, Cyril Castelbou, Frédéric Becq, Claude Férec, Reginald Philippe
Publikováno v:
Cell Calcium
Cell Calcium, Elsevier, 2017, 62, pp.47-59. ⟨10.1016/j.ceca.2017.01.011⟩
Cell Calcium, Vol. 62 (2017) pp. 47-59
Cell Calcium, Elsevier, 2017, 62, pp.47-59
Cell Calcium, Elsevier, 2017, 62, pp.47-59. ⟨10.1016/j.ceca.2017.01.011⟩
Cell Calcium, Vol. 62 (2017) pp. 47-59
Cell Calcium, Elsevier, 2017, 62, pp.47-59
International audience; Cystic Fibrosis (CF) is the most frequent fatal genetic disease in Caucasian populations. Mutations in the chloride channel CF Transmembrane Conductance Regulator (CFTR) gene are responsible for functional defects of the prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::729e96b052472448130ee0da231b53bd
https://hal.archives-ouvertes.fr/hal-01528587
https://hal.archives-ouvertes.fr/hal-01528587
Autor:
Réginald, Philippe, Fabrice, Antigny, Paul, Buscaglia, Caroline, Norez, Florentin, Huguet, Cyril, Castelbou, Pascal, Trouvé, Frédéric, Becq, Maud, Frieden, Claude, Férec, Olivier, Mignen
Publikováno v:
Cell calcium. 62
Cystic Fibrosis (CF) is the most frequent fatal genetic disease in Caucasian populations. Mutations in the chloride channel CF Transmembrane Conductance Regulator (CFTR) gene are responsible for functional defects of the protein and multiple associat
Autor:
E Durieu, Aurélien Chatelier, Clarisse Vandebrouck, Frédéric Becq, Fabrice Antigny, Nassima Oumata, Caroline Norez, Laurent Meijer, Patrick Bois, J. Bertrand, Hervé Galons, Sabrina Noël
Publikováno v:
British Journal of Pharmacology. 171:4831-4849
Background and Purpose The most common mutation in cystic fibrosis (CF), F508del, causes defects in trafficking, channel gating and endocytosis of the CF transmembrane conductance regulator (CFTR) protein. Because CF is an orphan disease, therapeutic
Publikováno v:
Journal of Cystic Fibrosis
Journal of Cystic Fibrosis, Elsevier, 2013, 12 (6), pp.584-91. ⟨10.1016/j.jcf.2013.05.008⟩
Journal of Cystic Fibrosis, Elsevier, 2013, 12 (6), pp.584-91. ⟨10.1016/j.jcf.2013.05.008⟩
International audience; BACKGROUND: TRPC6 has been proposed to be responsible for the abnormal OAG-dependent Ca(2+) influx in cystic fibrosis (CF) cells and we hypothesized that it interacts with CFTR. Here, we investigated how this functional comple