Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Caroline N, Herndon"'
Autor:
Matthew C. Hill, Bridget Simonson, Carolina Roselli, Ling Xiao, Caroline N. Herndon, Mark Chaffin, Helene Mantineo, Ondine Atwa, Harshit Bhasin, Yasmine Guedira, Kenneth C. Bedi, Kenneth B. Margulies, Carla A. Klattenhoff, Nathan R. Tucker, Patrick T. Ellinor
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Atrial fibrillation (AF) is the most common sustained arrhythmia in humans, yet the molecular basis of AF remains incompletely understood. To determine the cell type-specific transcriptional changes underlying AF, we perform single-nucleus R
Externí odkaz:
https://doaj.org/article/7b099e9da671463c89517f5597be9a33
Autor:
Kristin G. Ardlie, Nathan R. Tucker, Kenneth B. Margulies, Carolina Roselli, Seung Hoan Choi, Victoria A. Parsons, Christian Stegmann, Caroline N. Herndon, Amelia W. Hall, Patrick T. Ellinor, Stephen J. Fleming, Amer-Denis Akkad, Alessandro Arduini, Mehrtash Babadi, Kenneth Bedi, Irinna Papangeli, François Aguet, Mark Chaffin
Publikováno v:
Circulation
Circulation, 142(5), 466-482. LIPPINCOTT WILLIAMS & WILKINS
Circulation, 142(5), 466-482. LIPPINCOTT WILLIAMS & WILKINS
Background: The human heart requires a complex ensemble of specialized cell types to perform its essential function. A greater knowledge of the intricate cellular milieu of the heart is critical to increase our understanding of cardiac homeostasis an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e592b598e80d271b900003e17c5d9c29
https://europepmc.org/articles/PMC7666104/
https://europepmc.org/articles/PMC7666104/
Autor:
Alvaro Alonso, Donna M. Muzny, Moritz F. Sinner, Ching-Ti Liu, John Barnard, Eric Boerwinkle, David J. Milan, Thomas P. Cappola, Robert W. Mills, Alanna C. Morrison, Thomas Lumley, Colleen M. Sitlani, Dan E. Arking, Michael Morley, L. Adrienne Cupples, Nona Sotoodehnia, Rebecca D. Jackson, Mina K. Chung, Paul M.L. Janssen, Ning Li, Stephen S. Rich, Jerome I. Rotter, Christopher J. O'Donnell, David R. Van Wagoner, Kenneth B. Margulies, Xiaoyan Yin, Gus J. Vlahakes, Sara L. Pulit, Caroline N. Herndon, Vadim V. Fedorov, Joshua C. Bis, Susan R. Heckbert, Jared W. Magnani, Bruce M. Psaty, Steven A. Lubitz, Christopher Newton-Cheh, Honghuang Lin, Peter J. Mohler, Patrick T. Ellinor, Elena Dolmatova, Jonathan D. Smith, Vincenzo Macri, William J. Hucker, Emelia J. Benjamin, Richard A. Gibbs, Jennifer A. Brody
Publikováno v:
Circulation: Genomic and Precision Medicine. 11
Background: Genetic variants at the SCN5A / SCN10A locus are strongly associated with electrocardiographic PR and QRS intervals. While SCN5A is the canonical cardiac sodium channel gene, the role of SCN10A in cardiac conduction is less well character
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cc81b6fd2ed922f6ab9ec94ff3832ff
https://doi.org/10.1161/circgen.116.001663
https://doi.org/10.1161/circgen.116.001663
Autor:
Sudarvili Shanthalingam, Caroline N. Herndon, Renuka Subramaniam, Bindu Raghavan, Subramaniam Srikumaran, Jacobo S. Rodriguez, Danielle D. Nelson, Jegarubee Bavananthasivam, Sai Arun Batra, Ahmed Tibary, William J. Foreyt, Abirami Kugadas, Kathleen A. Potter
Publikováno v:
Veterinary Microbiology. 170:278-283
Bighorn sheep (BHS, Ovis canadensis) are much more susceptible than domestic sheep (DS, Ovis aries) to pneumonia caused by leukotoxin (Lkt)-producing members of the Family Pasteurellaceae, particularly Mannheimia haemolytica and Bibersteinia trehalos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1ad50d864dc5b797eab12e8d027ef9e
https://doi.org/10.1016/j.vetmic.2014.01.032
https://doi.org/10.1016/j.vetmic.2014.01.032
Autor:
Matthew C. Woodruff, Balthasar A. Heesters, Joanna R Groom, Michael C. Carroll, Shannon J. Turley, Caroline N. Herndon, Paul G. Thomas, Andrew D. Luster
Publikováno v:
Journal of experimental medicine, 211(8), 1611-1621. Rockefeller University Press
The Journal of Experimental Medicine
The Journal of Experimental Medicine
Resident lymph node DCs rapidly locate viral influenza antigen to drive early activation of T cells, resulting in germinal center formation and B cell memory.
Dendritic cells (DCs) are well established as potent antigen-presenting cells critical
Dendritic cells (DCs) are well established as potent antigen-presenting cells critical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf2e8b28f4a8593eb2f85511988b3592
https://doi.org/10.1084/jem.20132327
https://doi.org/10.1084/jem.20132327
Publikováno v:
Lymphatic Research and Biology. 11:121-127
As fluorescent microscopy has developed, significant insights have been gained into the establishment of immune response within secondary lymphoid organs, particularly in draining lymph nodes. While established techniques such as confocal imaging and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7094df95d9cc739c84514e54ae9b9239
https://doi.org/10.1089/lrb.2013.0011
https://doi.org/10.1089/lrb.2013.0011
Autor:
James F. Evermann, Lynn M. Herrmann-Hoesing, Subramaniam Srikumaran, Caroline N. Herndon, Renuka Subramaniam, William J. Foreyt, Donald P. Knowles, Gary J. Haldorson, Jegarubee Bavananthasivam, Sudarvili Shanthalingam, Rohana P. Dassanayake
Publikováno v:
Veterinary Microbiology. 162:166-172
Pneumonic bighorn sheep (BHS) have been found to be culture- and/or sero-positive for Bibersteinia trehalosi, respiratory syncytial virus (RSV), and parainfluenza-3 virus (PI-3). The objective of this study was to determine whether these pathogens ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fe0b5ff070493615e55d66141802a4b
https://doi.org/10.1016/j.vetmic.2012.08.029
https://doi.org/10.1016/j.vetmic.2012.08.029
Autor:
Vincenzo, Macri, Jennifer A, Brody, Dan E, Arking, William J, Hucker, Xiaoyan, Yin, Honghuang, Lin, Robert W, Mills, Moritz F, Sinner, Steven A, Lubitz, Ching-Ti, Liu, Alanna C, Morrison, Alvaro, Alonso, Ning, Li, Vadim V, Fedorov, Paul M, Janssen, Joshua C, Bis, Susan R, Heckbert, Elena V, Dolmatova, Thomas, Lumley, Colleen M, Sitlani, L Adrienne, Cupples, Sara L, Pulit, Christopher, Newton-Cheh, John, Barnard, Jonathan D, Smith, David R, Van Wagoner, Mina K, Chung, Gus J, Vlahakes, Christopher J, O'Donnell, Jerome I, Rotter, Kenneth B, Margulies, Michael P, Morley, Thomas P, Cappola, Emelia J, Benjamin, Donna, Muzny, Richard A, Gibbs, Rebecca D, Jackson, Jared W, Magnani, Caroline N, Herndon, Stephen S, Rich, Bruce M, Psaty, David J, Milan, Eric, Boerwinkle, Peter J, Mohler, Nona, Sotoodehnia, Patrick T, Ellinor
Publikováno v:
Circulation. Genomic and precision medicine. 11(5)
Genetic variants at theWe sequenced theWe identified 2 intronic single nucleotide polymorphisms in high linkage disequilibrium (Our findings suggest an association between genetic variation in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0ab60448479d990c9662801087def2c5
https://pubmed.ncbi.nlm.nih.gov/29752401
https://pubmed.ncbi.nlm.nih.gov/29752401
Autor:
Caroline N. Herndon, William J. Foreyt, Thomas E. Besser, Donald P. Knowles, Catherine Yamada, Kathleen A. Potter, Subramaniam Srikumaran, E. Frances Cassirer
Publikováno v:
Journal of Wildlife Diseases. 48:168-172
To test the hypothesis that Mycoplasma ovipneumoniae is an important agent of the bighorn sheep (Ovis canadensis) pneumonia that has previously inevitably followed experimental commingling with domestic sheep (Ovis aries), we commingled M. ovipneumon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e67a208164e1a1943f0cb069c79ac376
https://doi.org/10.7589/0090-3558-48.1.168
https://doi.org/10.7589/0090-3558-48.1.168
Autor:
Caroline N. Herndon, Donald P. Knowles, Subramaniam Srikumaran, Douglas R. Call, Sudarvili Shanthalingam
Publikováno v:
Clinical and Vaccine Immunology. 18:1133-1138
Mannheimia haemolytica consistently causes fatal bronchopneumonia in bighorn sheep (BHS; Ovis canadensis) under natural and experimental conditions. Leukotoxin is the primary virulence factor of this organism. BHS are more susceptible to developing f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44a5b625ab3bdcb6596e9fe981ae3fb0
https://doi.org/10.1128/cvi.00044-11
https://doi.org/10.1128/cvi.00044-11