Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Caroline Mullineaux-Sanders"'
Autor:
Caroline Mullineaux-Sanders, Zuzanna Kozik, Julia Sanchez-Garrido, Eve G. D. Hopkins, Jyoti S. Choudhary, Gad Frankel
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT Most studies of infections at mucosal surfaces have focused on the acute phase of the disease. Consequently, little is known about the molecular processes that underpin tissue recovery and the long-term consequences postinfection. Here, we c
Externí odkaz:
https://doaj.org/article/995e93328e20436a97071cba45032231
Autor:
Caroline Mullineaux-Sanders, Danielle Carson, Eve G. D. Hopkins, Izabela Glegola-Madejska, Alejandra Escobar-Zepeda, Hilary P. Browne, Trevor D. Lawley, Gad Frankel
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
Gut bacterial infections involve three-way interactions between virulence factors, the host immune responses, and the microbiome. While the microbiome erects colonization resistance barriers, pathogens employ virulence factors to overcome them.
Externí odkaz:
https://doaj.org/article/26b6e62002a94344be6faf9d79c3a812
Autor:
David G. Glanville, Caroline Mullineaux-Sanders, Christopher J. Corcoran, Brian T. Burger, Saheed Imam, Timothy J. Donohue, Andrew T. Ulijasz
Publikováno v:
mSystems, Vol 6, Iss 1 (2021)
ABSTRACT Heme is an essential metabolite for most life on earth. Bacterial pathogens almost universally require iron to infect a host, often acquiring this nutrient in the form of heme. The Gram-negative pathogen Pseudomonas aeruginosa is no exceptio
Externí odkaz:
https://doaj.org/article/b560ad3da8974fd3a79543afb6cd13cb
Autor:
Caroline Mullineaux-Sanders, James W. Collins, David Ruano-Gallego, Maayan Levy, Meirav Pevsner-Fischer, Izabela T. Glegola-Madejska, Agnes M. Sågfors, Joshua L.C. Wong, Eran Elinav, Valerie F. Crepin, Gad Frankel
Publikováno v:
Cell Reports, Vol 21, Iss 12, Pp 3381-3389 (2017)
Summary: We investigated the role of commensals at the peak of infection with the colonic mouse pathogen Citrobacter rodentium. Bioluminescent and kanamycin (Kan)-resistant C. rodentium persisted avirulently in the cecal lumen of mice continuously tr
Externí odkaz:
https://doaj.org/article/7ea88cecb2fd495fb66456bd2dcd639d
Autor:
Eve G. D. Hopkins, Theodoros I. Roumeliotis, Caroline Mullineaux-Sanders, Jyoti S. Choudhary, Gad Frankel
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
ABSTRACT We used the mouse attaching and effacing (A/E) pathogen Citrobacter rodentium, which models the human A/E pathogens enteropathogenic Escherichia coli and enterohemorrhagic E. coli (EPEC and EHEC), to temporally resolve intestinal epithelial
Externí odkaz:
https://doaj.org/article/a67581a0f3b94343866cb0b1dbcd1ec0
Autor:
Caroline Mullineaux-Sanders, Sharanya Chatterjee, Julia Sanchez-Garrido, Gad Frankel, Lucrecia Alberdi
Publikováno v:
Current Opinion in Microbiology. 64:19-26
Citrobacter rodentium, a natural mouse pathogen which colonises the colon of immuno-competent mice, provides a robust model for interrogating host-pathogen-microbiota interactions in vivo. This model has been key to providing new insights into local
Autor:
Izabela Glegola-Madejska, Gad Frankel, Caroline Mullineaux-Sanders, Alejandra Escobar-Zepeda, Trevor D. Lawley, Eve G D Hopkins, Hilary P. Browne, Danielle Carson
Publikováno v:
mBio
mBio, Vol 12, Iss 5 (2021)
mBio, Vol 12, Iss 5 (2021)
The gut microbiota plays a crucial role in susceptibility to enteric pathogens, including Citrobacter rodentium, a model extracellular mouse pathogen that colonizes the colonic mucosa. C. rodentium infection outcomes vary between mouse strains, with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f44d31ca709a92977a96741c3a22a547
http://hdl.handle.net/10044/1/91671
http://hdl.handle.net/10044/1/91671
Autor:
Caroline Mullineaux-Sanders, Theodoros I. Roumeliotis, Massiel Cepeda-Molero, David Ruano-Gallego, Izabela Glegola-Madejska, Jyoti S. Choudhary, Naama Wagner, Alfonso Rodríguez-Patón, Tal Pupko, Zuzanna Kozik, Elena Núñez-Berrueco, Luis Ángel Fernández, Sabrina L. Slater, Gad Frankel, Julia Sanchez-Garrido, Jasmine Naemi-Baghshomali Clark
Publikováno v:
DIGITAL.INTA Repositorio Digital del Instituto Nacional de Técnica Aeroespacial
instname
instname
INTRODUCTION Infections with many Gram-negative pathogens, including Escherichia coli, Salmonella, Shigella, and Yersinia, rely on the injection of effectors via type III secretion systems (T3SSs). The effectors hijack cellular processes through mult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4a0310bdf1639a68da27021824eab27
https://hdl.handle.net/20.500.12666/555
https://hdl.handle.net/20.500.12666/555
Autor:
Saheed Imam, Timothy J. Donohue, David G. Glanville, Christopher J. Corcoran, Brian Burger, Caroline Mullineaux-Sanders, Andrew T. Ulijasz
Publikováno v:
mSystems
mSystems, Vol 6, Iss 1 (2021)
mSystems, Vol 6, Iss 1 (2021)
The ability to simultaneously and more directly correlate genes with metabolite levels on a global level would provide novel information for many biological platforms yet has thus far been challenging. Here, we describe a method to help address this
Publikováno v:
Nature Microbiology. 3:132-140
The development of innovative high-throughput genomics and metabolomics technologies has considerably expanded our understanding of the commensal microorganisms residing within the human body, collectively termed the microbiota. In recent years, the