Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Caroline Mota Fernandes"'
Autor:
Natalia Kronbauer Oliveira, Kyungyoon Yoo, Somanon Bhattacharya, Rina Gambhir, Nigina Kirgizbaeva, Pilar Arcones García, Ignacio Pompa Prados, Caroline Mota Fernandes, Maurizio Del Poeta, Bettina C. Fries
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Cryptococcus neoformans (Cn) is an opportunistic yeast that causes meningoencephalitis in immunocompromised individuals. Calorie restriction (CR) prolongs Cn replicative lifespan (RLS) and mimics low-glucose environments in which Cn resides
Externí odkaz:
https://doaj.org/article/78c0f3c0c09d423cb4a64e7faae09013
Autor:
Isabella Dib Ferreira Gremião, Gabriela Reis Pereira-Oliveira, Sandro Antonio Pereira, Maria Lopes Corrêa, Luana Pereira Borba-Santos, Alessandra Lifsitch Viçosa, Ashna Garg, Krupanandan Haranahalli, Deveney Dasilva, Nivea Pereira de Sa, Gabriel S. Matos, Vanessa Silva, Cristina Lazzarini, Caroline Mota Fernandes, Kildare Miranda, Jhon Jhamilton Artunduaga Bonilla, Anna Letícia Nunes, Leonardo Nimrichter, Iwao Ojima, John Mallamo, John B. McCarthy, Maurizio Del Poeta
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 6 (2024)
ABSTRACT Acylhydrazone (AH) derivatives represent a novel category of anti-fungal medications that exhibit potent activity against Sporothrix sp., both in vitro and in a murine model of sporotrichosis. In this study, we demonstrated the anti-fungal e
Externí odkaz:
https://doaj.org/article/9a2aba0c9d7847cbb62ff4a8532b18f8
Autor:
Liping Xiong, Nivea Pereira De Sa, Robert Zarnowski, Manning Y Huang, Caroline Mota Fernandes, Frederick Lanni, David R Andes, Maurizio Del Poeta, Aaron P Mitchell
Publikováno v:
PLoS Pathogens, Vol 20, Iss 5, p e1012225 (2024)
Biofilm formation by the fungal pathogen Candida albicans is the basis for its ability to infect medical devices. The metabolic gene ERG251 has been identified as a target of biofilm transcriptional regulator Efg1, and here we report that ERG251 is r
Externí odkaz:
https://doaj.org/article/29da080bdb6443be8269d4051846cc2b
Autor:
João Henrique Tadini Marilhano Fabri, Marina Campos Rocha, Caroline Mota Fernandes, Jonatas Erick Maimoni Campanella, Anderson Ferreira da Cunha, Maurizio Del Poeta, Iran Malavazi
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Thermotolerance is a remarkable virulence attribute of Aspergillus fumigatus, but the consequences of heat shock (HS) to the cell membrane of this fungus are unknown, although this structure is one of the first to detect changes in ambient t
Externí odkaz:
https://doaj.org/article/037e0139b7a542278ca22c4f029dc2e4
Autor:
Nivea Pereira de Sa, Kalani Jayanetti, Dominick Rendina, Timothy Clement, Veronica Soares Brauer, Caroline Mota Fernandes, Iwao Ojima, Michael V. Airola, Maurizio Del Poeta
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT Invasive fungal infections are a leading cause of death in immunocompromised patients. Current therapies have several limitations, and innovative antifungal agents are critically needed. Previously, we identified the fungus-specific enzyme s
Externí odkaz:
https://doaj.org/article/10a62aeb5767483fa4514f5d67e00b54
Autor:
Caroline Mota Fernandes, Tyler G. Normile, Joao Henrique Tadini Marilhano Fabri, Veronica Soares Brauer, Glauber R. de S. Araújo, Susana Frases, Leonardo Nimrichter, Iran Malavazi, Maurizio Del Poeta
Publikováno v:
mBio, Vol 13, Iss 5 (2022)
ABSTRACT Aspergillus fumigatus causes invasive aspergillosis (IA) in immunocompromised patients, resulting in high mortality rates. Currently, no vaccine formulations to promote immune protection in at-risk individuals have been developed. In this wo
Externí odkaz:
https://doaj.org/article/64fcee8035134ad1a05e76da7106cd8f
Autor:
Jakub Zahumenský, Caroline Mota Fernandes, Petra Veselá, Maurizio Del Poeta, James B. Konopka, Jan Malínský
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 4 (2022)
ABSTRACT Sphingolipids are essential building blocks of eukaryotic membranes and important signaling molecules that are regulated tightly in response to environmental and physiological inputs. While their biosynthetic pathway has been well-described,
Externí odkaz:
https://doaj.org/article/aeacbcde1ecf440c98ec1449610fafdd
Autor:
Thaila Fernanda dos Reis, Maria Augusta Crivelente Horta, Ana Cristina Colabardini, Caroline Mota Fernandes, Lilian Pereira Silva, Rafael Wesley Bastos, Maria Vitória de Lazari Fonseca, Fang Wang, Celso Martins, Márcio L. Rodrigues, Cristina Silva Pereira, Maurizio Del Poeta, Koon Ho Wong, Gustavo H. Goldman
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT Aspergillus fumigatus is an important fungal pathogen and the main etiological agent of aspergillosis, a disease characterized by a noninvasive process that can evolve to a more severe clinical manifestation, called invasive pulmonary asperg
Externí odkaz:
https://doaj.org/article/df0e79e5ab2e41ef86dd3dc64c5b821a
Autor:
João Henrique Tadini Marilhano Fabri, Marina Campos Rocha, Caroline Mota Fernandes, Gabriela Felix Persinoti, Laure Nicolas Annick Ries, Anderson Ferreira da Cunha, Gustavo Henrique Goldman, Maurizio Del Poeta, Iran Malavazi
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
The deleterious effects of human-induced climate change have long been predicted. However, the imminent emergence and spread of new diseases, including fungal infections through the rise of thermotolerant strains, is still neglected, despite being a
Externí odkaz:
https://doaj.org/article/a9aae531c2db43a3a97fcdf238391131
Autor:
Xiao-Hong Liu, Shuang Liang, Yun-Yun Wei, Xue-Ming Zhu, Lin Li, Ping-Ping Liu, Qing-Xia Zheng, Hui-Na Zhou, Yong Zhang, Li-Juan Mao, Caroline Mota Fernandes, Maurizio Del Poeta, Naweed I. Naqvi, Fu-Cheng Lin
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT The blast fungus initiates infection using a heavily melanized, dome-shaped infection structure known as the appressorium, which forcibly ruptures the cuticle to enter the rice leaf tissue. How this process takes place remains not fully unde
Externí odkaz:
https://doaj.org/article/c3495fadcb6345b39a5b88071cf52395