Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Caroline McGoohan"'
Autor:
Clare Nicholson, Peter W. Hamilton, Meenakshi Mirakhur, David W. Ellison, James Diamond, Patrick G. Johnston, Christopher J. Scott, Chirag Patel, D. McCormick, Caroline McGoohan, Brian Walker, Gordon McGregor, Gordon Cran, Thomas Flannery, David Mendelow, Lorraine Martin, Rob McConnell, Stephen McQuaid
Publikováno v:
International Journal of Cancer. 119:854-860
Cysteine proteinases have been implicated in astrocytoma invasion. We recently demonstrated that cathepsin S (CatS) expression is up-regulated in astrocytomas and provided evidence for a potential role in astrocytoma invasion (Flannery et al., Am J P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76f4b10b3e2df3da761c83616554f524
https://doi.org/10.1002/ijc.21911
https://doi.org/10.1002/ijc.21911
Autor:
Caroline McGoohan, Christian Laggner, Clemens Feldmann, Gerhard Wolber, Simona Distinto, Brian Walker, Patrick Markt, Johannes Kirchmair, Gudrun M. Spitzer, Thierry Langer, Gabriella De Martino, Daniela Schuster
Publikováno v:
Journal of chemical information and modeling. 48(8)
The cysteine protease cathepsin S (CatS) is involved in the pathogenesis of autoimmune disorders, atherosclerosis, and obesity. Therefore, it represents a promising pharmacological target for drug development. We generated ligand-based and structure-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30a7cbfaf2195c89048517bf9249b960
https://pubmed.ncbi.nlm.nih.gov/18637674
https://pubmed.ncbi.nlm.nih.gov/18637674
Autor:
Stephen McQuaid, Patrick G. Johnston, G McGregor, Rob McConnell, Caroline McGoohan, Lorraine Martin, Christopher J. Scott, Meenakshi Mirakhur, Brian Walker, Thomas Flannery, Roberta E. Burden
Publikováno v:
British journal of neurosurgery. 21(2)
Microdialysis enables the chemistry of extracellular fluid in body tissues to be measured. Extracellular proteases such as the cysteine protease, cathepsin S (CatS), are thought to facilitate astrocytoma invasion. Microdialysates obtained from human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a67c67ff6706759dd3b41264014c3cf
https://pubmed.ncbi.nlm.nih.gov/17453790
https://pubmed.ncbi.nlm.nih.gov/17453790
Autor:
Caroline McGoohan, Christopher J. Scott, Brendan Gilmore, Lorraine Martin, Brian Walker, John F. Lynas
Publikováno v:
Biochemical and biophysical research communications. 346(2)
Dipeptidyl peptidase IV (DPP-IV) and seprase belong to a small group of membrane-bound, proline-specific serine proteases, the serine integral membrane proteases (SIMPs). Whilst DPP-IV is the most exhaustively studied peptidase in this class, relativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2a9df9cda69997cc302652d79f4ca6d
https://pubmed.ncbi.nlm.nih.gov/16769036
https://pubmed.ncbi.nlm.nih.gov/16769036
Autor:
Richard D. Kennedy, Nuala McCabe, Steven Walker, Caroline McGoohan, Steve Deharo, Gavin R. Oliver, D. Paul Harkin, F. A. McDyer, Patrick G. Johnston
Publikováno v:
Cancer Research. 70:1153-1153
Prostate cancer is the second leading cause of cancer-related deaths in men; specifically one in six men are diagnosed with prostate cancer in their lifetime. The use of serum prostate-specific antigen (PSA) levels has been lauded as a huge step forw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48f428f33f70cb5ccbc304865316a137
https://doi.org/10.1158/1538-7445.am10-1153
https://doi.org/10.1158/1538-7445.am10-1153
Autor:
Lorraine Martin, John F. Lynas, Caroline McGoohan, Brian Walker, Brendan Gilmore, Christopher J. Scott
Publikováno v:
Biochemical and Biophysical Research Communications. 376:242
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e2e0e9f37e970f132fd310fc82eb590
https://doi.org/10.1016/j.bbrc.2008.08.086
https://doi.org/10.1016/j.bbrc.2008.08.086
Autor:
Patrick Markt, Caroline McGoohan, Brian Walker, Johannes Kirchmair, Clemens Feldmann, Gabriella De Martino, Gudrun Spitzer, Simona Distinto, Daniela Schuster, Gerhard Wolber, Christian Laggner, Thierry Langer
Publikováno v:
Journal of Chemical Information & Modeling; Jul2008, Vol. 48 Issue 8, p1693-1705, 13p