Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Caroline Mauvezin"'
Autor:
Baraa Abuasaker, Eduardo Garrido, Marta Vilaplana, Jesús Daniel Gómez-Zepeda, Sonia Brun, Marta Garcia-Cajide, Caroline Mauvezin, Montserrat Jaumot, Maria Dolors Pujol, Jaime Rubio-Martínez, Neus Agell
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 748 (2023)
KRAS is the most frequently mutated oncogene associated with the genesis and progress of pancreatic, lung and colorectal (CRC) tumors. KRAS has always been considered as a therapeutic target in cancer but until now only two compounds that inhibit one
Externí odkaz:
https://doaj.org/article/b37dca4cc01e466184cf97793aaabb57
Autor:
Eugènia Almacellas, Joffrey Pelletier, Anna Manzano, Antonio Gentilella, Santiago Ambrosio, Caroline Mauvezin, Albert Tauler
Publikováno v:
iScience, Vol 20, Iss , Pp 434-448 (2019)
Summary: Cancer cells rely on mTORC1 activity to coordinate mitogenic signaling with nutrients availability for growth. Based on the metabolic function of E2F1, we hypothesize that glucose catabolism driven by E2F1 could participate on mTORC1 activat
Externí odkaz:
https://doaj.org/article/f4a8cf5de87c408289386e3ddc47fa44
Autor:
David Sebastián, Maria Guitart, Celia García-Martínez, Caroline Mauvezin, Josep M. Orellana-Gavaldà, Dolors Serra, Anna M. Gómez-Foix, Fausto G. Hegardt, Guillermina Asins
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 9, Pp 1789-1799 (2009)
Carnitine palmitoyltransferase 1 (CPT1) catalyzes the first step in long-chain fatty acid import into mitochondria, and it is believed to be rate limiting for β-oxidation of fatty acids. However, in muscle, other proteins may collaborate with CPT1.
Externí odkaz:
https://doaj.org/article/069441f7ea6a4cedbed24ed50be6c5e5
Publikováno v:
Cells, Vol 6, Iss 3, p 22 (2017)
Autophagy is a catabolic process in eukaryotic cells promoting bulk or selective degradation of cellular components within lysosomes. In recent decades, several model systems were utilized to dissect the molecular machinery of autophagy and to identi
Externí odkaz:
https://doaj.org/article/6578e1a9a43e4db4b54ad28122a75e66
Autor:
Ana Sancho, Jordi Duran, Antonio García-España, Caroline Mauvezin, Endalkachew A Alemu, Trond Lamark, Maria J Macias, Rob DeSalle, Miriam Royo, David Sala, Javier U Chicote, Manuel Palacín, Terje Johansen, Antonio Zorzano
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e34034 (2012)
Human DOR/TP53INP2 displays a unique bifunctional role as a modulator of autophagy and gene transcription. However, the domains or regions of DOR that participate in those functions have not been identified. Here we have performed structure/function
Externí odkaz:
https://doaj.org/article/f4592fb024084229acac77dc5f3623ca
Autor:
Ana Sancho, Jordi Duran, Antonio García-España, Caroline Mauvezin, Endalkachew A. Alemu, Trond Lamark, Maria J. Macias, Rob DeSalle, Miriam Royo, David Sala, Javier U. Chicote, Manuel Palacín, Terje Johansen, Antonio Zorzano
Publikováno v:
PLoS ONE, Vol 7, Iss 5 (2012)
Externí odkaz:
https://doaj.org/article/3b80435aa15c4a68920ec3dfdc89f3b5
Autor:
Carles Pons, Caroline Mauvezin
The toroidal nucleus is a novel chromosomal instability (CIN) biomarker which complements the micronucleus. Understanding the specific biological stresses leading to the formation of each CIN-associated phenotype requires the evaluation of large pane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b8b65998641e9302d5739562961de4b
https://doi.org/10.1101/2022.11.07.515391
https://doi.org/10.1101/2022.11.07.515391
Autor:
Eugènia Almacellas, Caroline Mauvezin
Publikováno v:
Journal of cell science. 135(11)
Lysosomes exert pleiotropic functions to maintain cellular homeostasis and degrade autophagy cargo. Despite the great advances that have boosted our understanding of autophagy and lysosomes in both physiology and pathology, their function in mitosis
Autor:
Santiago Ambrosio, Eugènia Almacellas, Joffrey Pelletier, Albert Tauler, Charles A. Day, Caroline Mauvezin
Publikováno v:
Autophagy
article-version (VoR) Version of Record
Dipòsit Digital de la UB
Universidad de Barcelona
article-version (VoR) Version of Record
Dipòsit Digital de la UB
Universidad de Barcelona
Lysosomes, as primary degradative organelles, are the endpoint of different converging pathways, including macroautophagy. To date, lysosome degradative function has been mainly studied in interphase cells, while their role during mitosis remains con
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2445
Chromosomal instability (CIN) is a hallmark of cancer, which is characterized by the gain or loss of chromosomes as well as the rearrangement of the genetic material during cell division. Detection of mitotic errors such as misaligned chromosomes or