Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Caroline M.M. Gits"'
Autor:
Azadeh Amirnasr, Caroline M.M. Gits, Patricia F. van Kuijk, Marcel Smid, Anne L.M. Vriends, Piotr Rutkowski, Raf Sciot, Patrick Schöffski, Maria Debiec-Rychter, Stefan Sleijfer, Erik A. C. Wiemer
Publikováno v:
Cancers, Vol 11, Iss 6, p 882 (2019)
Despite the success of imatinib in advanced gastrointestinal stromal tumor (GIST) patients, 50% of the patients experience resistance within two years of treatment underscoring the need to get better insight into the mechanisms conferring imatinib re
Externí odkaz:
https://doaj.org/article/b2780d72ee3441ab9a1863fcfeb36bd7
Autor:
Maria Debiec-Rychter, Patricia F. van Kuijk, Marcel Smid, Stefan Sleijfer, Piotr Rutkowski, Patrick Schöffski, Erik A.C. Wiemer, Raf Sciot, Caroline M.M. Gits, Anne L.M. Vriends, Azadeh Amirnasr
Publikováno v:
Cancers, 11(6):882. Multidisciplinary Digital Publishing Institute (MDPI)
Cancers
Cancers, Vol 11, Iss 6, p 882 (2019)
Volume 11
Issue 6
Cancers
Cancers, Vol 11, Iss 6, p 882 (2019)
Volume 11
Issue 6
Despite the success of imatinib in advanced gastrointestinal stromal tumor (GIST) patients, 50% of the patients experience resistance within two years of treatment underscoring the need to get better insight into the mechanisms conferring imatinib re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4ca218afe3cf8c4ed2a1bae12a83062
https://pure.eur.nl/en/publications/5697bb36-8591-43cc-b0c6-564c3141e477
https://pure.eur.nl/en/publications/5697bb36-8591-43cc-b0c6-564c3141e477
Autor:
Jean-Michel Coindre, Caroline M.M. Gits, Stefan Sleijfer, Cornelis Verhoef, Michael A. den Bakker, Antonius W. M. Boersma, Marcel Smid, Frédéric Chibon, Ron H.J. Mathijssen, Moniek B E Jonkers, Erik A.C. Wiemer, Jaap Verweij, Patricia F. van Kuijk, Wilfred F. J. van IJcken
Publikováno v:
International Journal of Cancer. 135:348-361
Liposarcomas are rare, heterogeneous and malignant tumors that can be divided into four histological subtypes with different characteristics and clinical behavior. Treatment consists of surgery in combination with systemic chemotherapy, but neverthel
Autor:
Erik A.C. Wiemer, Patrick Schöffski, Antonius W. M. Boersma, Stefan Sleijfer, Caroline M.M. Gits, Ron H.J. Mathijssen, Moniek B E Jonkers, W F J van IJcken, Agnieszka Wozniak, Piotr Rutkowski, P F van Kuijk, Raf Sciot, Jaap Verweij, Takahiro Taguchi, Maria Debiec-Rychter
Publikováno v:
British Journal of Cancer, 109(6), 1625-1635. Nature Publishing Group
British Journal of Cancer
British Journal of Cancer
BACKGROUND: Gastrointestinal stromal tumours (GIST) are characterised by high expression of KIT and ETV1, which cooperate in GIST oncogenesis. Our aim was to identify microRNAs that are deregulated in GIST, have a role in GIST pathogenesis, and could
Autor:
Erik A.C. Wiemer, Patricia F. van Kuijk, Stefan Sleijfer, Marcel Smid, Azadeh Amirnasr, Caroline M.M. Gits, Maria Debiec-Rychter
Publikováno v:
Cancer Research. 78:4345-4345
Background and aim: Gastrointestinal stromal tumors (GISTs) are rare mesenchymal tumors of the gastrointestinal tract. Gain-of-function mutations in KIT or, less frequently, PDGFRA underlie the pathogenesis of the majority of these tumors. The introd
Autor:
Erik A.C. Wiemer, Jonneke C.W.M. de Rijck, Ron H.J. Mathijssen, Nikky Muskens, Jaap Verweij, Moniek B E Jonkers, Patricia F. van Kuijk, Wilfred F. J. van IJcken, Caroline M.M. Gits, Stefan Sleijfer
Publikováno v:
BMC Cancer, 14. BioMed Central Ltd.
BMC Cancer
BMC Cancer
Background Hypoxia is often encountered in solid tumors and known to contribute to aggressive tumor behavior, radiation- and chemotherapy resistance resulting in a poor prognosis for the cancer patient. MicroRNAs (miRNAs) play a role in the regulatio
Autor:
Stefan Sleijfer, Patricia F. van Kuijk, Caroline M.M. Gits, Erik A.C. Wiemer, Jonneke C.W.M. de Rijck, Moniek B E Jonkers, Jaap Verweij
Publikováno v:
Cancer Research. 71:A5-A5
Many solid tumors encounter hypoxia; a state in which the tumor tissue is deprived of oxygen. Hypoxia is of great clinical importance since it promotes malignant progression by increasing genetic instability, angiogenesis, local invasion and distant