Výsledky vyhledávání - "Caroline M. Hodin"

Reduced Paneth cell antimicrobial protein levels correlate with activation of the unfolded protein response in the gut of obese individuals

Autor: Caroline M. Hodin, Fons Verheyen, Froukje J. Verdam, Joep Grootjans, Wim A. Buurman, Kaatje Lenaerts, Sander S. Rensen, Cornelis H. C. Dejong, Jan Greve

Publikováno v: The Journal of Pathology. 225:276-284

The intestinal microbiota is increasingly acknowledged to play a crucial role in the development of obesity. A shift in intestinal microbiota composition favouring the presence of Firmicutes over Bacteroidetes has been observed in obese subjects. A s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2b8d0273b55a68d8a94a7e798e82c5f3
https://doi.org/10.1002/path.2917

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Localization of the lipopolysaccharide recognition complex in the human healthy and inflamed premature and adult gut

Autor: Charles L. Bevins, Joris Vanderlocht, Caroline M. Hodin, Wim A. Buurman, Wim G. van Gemert, Ann Driessen, Felix Lasitschka, Nikolaus Gassler, Tim G. A. M. Wolfs, Adriaan P. de Bruïne, Joep P. M. Derikx

Publikováno v: Inflammatory Bowel Diseases, 16(1), 68-75. LIPPINCOTT WILLIAMS & WILKINS

Background: Microbiota in the intestinal lumen provide an abundant source of potentially detrimental antigens, including lipopolysaccharide (LPS), a potent immunostimulatory product of Gram-negative bacteria recognized by the host via TLR-4 and MD-2.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a0854e842b7a5e2b77a904d89d06fb
https://doi.org/10.1002/ibd.20995

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Regulated Proteolysis of NOTCH2 and NOTCH3 Receptors by ADAM10 and Presenilins

Autor: Jan Theys, Paul Saftig, Sanaz Yahyanejad, Marc Vooijs, Karina Reiss, Caroline M. Hodin, Arjan J. Groot, Roger Habets

Publikováno v: Molecular and Cellular Biology, 34(15), 2822-2832. American Society for Microbiology

In mammals, there are four NOTCH receptors and five Delta-Jagged-type ligands regulating many aspects of embryonic development and adult tissue homeostasis. NOTCH proteins are type I transmembrane receptors that interact with ligands on adjacent cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0a1b9b3acc95f0df041370428b2b309
https://cris.maastrichtuniversity.nl/en/publications/92c0580c-1f6e-4f0a-b166-600904307c8d

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Lipid-rich enteral nutrition regulates mucosal mast cell activation via the vagal anti-inflammatory reflex

Autor: M'hamed Hadfoune, Cathy Cailotto, Jacco J. de Haan, Tim Lubbers, Wouter J. de Jonge, Akihiko Ito, Jan Greve, Kaatje Lenaerts, Isabelle Verbaeys, Michael J. Skynner, Caroline M. Hodin, Jan van der Vliet, Wim A. Buurman

Publikováno v: American Journal of Physiology : Gastrointestinal and Liver Physiology, 305, 5, pp. G383-91
American journal of physiology. Gastrointestinal and liver physiology, 305(5), G383-G391. American Physiological Society
American Journal of Physiology : Gastrointestinal and Liver Physiology, 305, G383-91
American Journal of Physiology-Gastrointestinal and Liver Physiology, 305(5), G383-G391. American Physiological Society

Nutritional stimulation of the cholecystokinin-1 receptor (CCK-1R) and nicotinic acetylcholine receptor (nAChR)-mediated vagal reflex was shown to reduce inflammation and preserve intestinal integrity. Mast cells are important early effectors of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65ba3ed21d9263da1fc2a76cbe02310f
https://hdl.handle.net/2066/185170

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Total parenteral nutrition induces a shift in the Firmicutes to Bacteroidetes ratio in association with Paneth cell activation in rats

Autor: Caroline M, Hodin, Ruben G J, Visschers, Sander S, Rensen, Bas, Boonen, Steven W M, Olde Damink, Kaatje, Lenaerts, Wim A, Buurman

Publikováno v: The Journal of nutrition. 142(12)

The use of total parenteral nutrition (TPN) in the treatment of critically ill patients has been the subject of debate because it has been associated with disturbances in intestinal homeostasis. Important factors in maintaining intestinal homeostasis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::98c78924f4b99c7421f7f0df5b1dee68
https://pubmed.ncbi.nlm.nih.gov/23096015

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Reduced Paneth cell antimicrobial protein levels correlate with activation of the unfolded protein response in the gut of obese individuals

Autor: Caroline M, Hodin, Froukje J, Verdam, Joep, Grootjans, Sander S, Rensen, Fons K, Verheyen, Cornelis H C, Dejong, Wim A, Buurman, Jan Willem, Greve, Kaatje, Lenaerts

Publikováno v: The Journal of pathology. 225(2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::06718c0e4a99d8041b22958c3b867005
https://pubmed.ncbi.nlm.nih.gov/21630271

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Starvation compromises paneth cells

Autor: Fons Verheyen, Hiroshi Kiyama, Caroline M. Hodin, Wim A. Buurman, Jacco J de Haan, Joep Grootjans, M'hamed Hadfoune, Kaatje Lenaerts, Erik Heineman

Publikováno v: American Journal of Pathology, 179(6), 2885-2893. Elsevier Science
The American Journal of Pathology, 179(6), 2885-2893. ELSEVIER SCIENCE INC

Lack of enteral feeding, with or without parenteral nutritional support, is associated with increased intestinal permeability and translocation of bacteria. Such translocation is thought to be important in the high morbidity and mortality rates of pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ef24c6f1abcf847f7a7786a5e6318c0
https://cris.maastrichtuniversity.nl/en/publications/d13be4f9-0727-4dba-b25f-42ec4daa390e

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Hemolysis results in impaired intestinal microcirculation and intestinal epithelial cell injury

Autor: Caroline M. Hodin, Michael J. Jacobs, Frits W. Prinzen, Tim Lubbers, Wim A. Buurman, Sebastiaan J. Hanssen

Publikováno v: World Journal of Gastroenterology, 17(2), 213-218. Baishideng Publishing Group Inc

AIM: To study the effect of circulating cell-free oxyhemoglobin (FHb) on intestinal microcirculation and intestinal epithelial injury in a rat model. METHODS: To induce elevated intravascular circulating FHb, male Sprague-Dawley rats received water o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2a37fc722dca649264ab74558baade3
https://cris.maastrichtuniversity.nl/en/publications/09d3a069-9824-433f-a3b4-d978195bdfe6

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