Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Caroline M. Hinesley"'
Autor:
Michael J. Cotton, Pablo Ariel, Kaiwen Chen, Vanessa A. Walcott, Michelle Dixit, Keith A. Breau, Caroline M. Hinesley, Katarzyna M. Kedziora, Cynthia Y. Tang, Anna Zheng, Scott T. Magness, Joseph Burclaff
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract The intestinal epithelium dynamically controls cell cycle, yet no experimental platform exists for directly analyzing cell cycle phases in non-immortalized human intestinal epithelial cells (IECs). Here, we present two reporters and a comple
Externí odkaz:
https://doaj.org/article/2166ab0898f7409294e33d7ee9771520
Autor:
Kristina R. Rivera, R. Jarrett Bliton, Joseph Burclaff, Michael J. Czerwinski, Jintong Liu, Jessica M. Trueblood, Caroline M. Hinesley, Keith A. Breau, Halston E. Deal, Shlok Joshi, Vladimir A. Pozdin, Ming Yao, Amanda L. Ziegler, Anthony T. Blikslager, Michael A. Daniele, Scott T. Magness
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 16, Iss 5, Pp 823-846 (2023)
Background and Aims: Hypoxia in the intestinal epithelium can be caused by acute ischemic events or chronic inflammation in which immune cell infiltration produces inflammatory hypoxia starving the mucosa of oxygen. The epithelium has the capacity to
Externí odkaz:
https://doaj.org/article/4c003ca116b84e8fb51d880c837e2004
Autor:
Meryem T. Ok, Jintong Liu, R. Jarrett Bliton, Caroline M. Hinesley, Ekaterina Ellyce T. San Pedro, Keith A. Breau, Ismael Gomez-Martinez, Joseph Burclaff, Scott T. Magness
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 324:G262-G280
Novel human colonocyte monolayer cultures, benchmarked by transcriptomics for physiological relevance, detect early cytopathic impacts of Clostridioides difficile toxins TcdA and TcdB. A fluorescent ZO-1 reporter in primary human colonocytes is used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c51352ac1a72cc1720eb939384b23e05
https://doi.org/10.1152/ajpgi.00251.2022
https://doi.org/10.1152/ajpgi.00251.2022
Autor:
Kristina R. Rivera, R. Jarrett Bliton, Joseph Burclaff, Michael J. Czerwinski, Jintong Liu, Jessica M. Trueblood, Caroline M. Hinesley, Keith A Breau, Shlok Joshi, Vladimir A. Pozdin, Ming Yao, Amanda L. Ziegler, Anthony T. Blikslager, Michael A. Daniele, Scott T. Magness
Publikováno v:
bioRxiv
Background & AimsHypoxia in the intestinal epithelium can be caused by acute ischemic events or conditions like Inflammatory Bowel Disease (IBD) where immune cell infiltration produces ‘inflammatory hypoxia’, a chronic condition that starves the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24136f3a7aea390d6fcd612e7ed025d0
https://doi.org/10.1101/2023.01.31.524747
https://doi.org/10.1101/2023.01.31.524747
Autor:
Joseph Burclaff, R. Jarrett Bliton, Keith A Breau, Michael J Cotton, Caroline M Hinesley, Meryem T Ok, Caden W Sweet, Anna Zheng, Eric D Bankaitis, Pablo Ariel, Scott T Magness
Background and AimsThe transcription factor SOX9 is expressed in many stem/progenitor cell populations and has biphasic correlations with proliferation rates across different biological systems. In murine intestinal crypts, distinct Sox9 levels mark
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::248ecbb35497d7028a060db785c2797c
https://doi.org/10.1101/2022.11.03.514885
https://doi.org/10.1101/2022.11.03.514885
Autor:
Meryem T. Ok, Jintong Liu, R. Jarrett Bliton, Caroline M. Hinesley, Ekaterina Ellyce T. San Pedro, Keith A. Breau, Ismael Gomez-Martinez, Joseph Burclaff, Scott T. Magness
Background & AimsClostridioides difficile(C. difficile) toxins A (TcdA) and B (TcdB) cause antibiotic-associated colitis and increase morbidity and mortality. Accurate in vitro models are necessary to detect early toxicity kinetics, investigate disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5a5be8fb6c5fda0140f8bc9c64db605
https://doi.org/10.1101/2022.10.13.511617
https://doi.org/10.1101/2022.10.13.511617