Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Caroline M. Grunenwald"'
Autor:
Hualiang Pi, Andy Weiss, Clare L. Laut, Caroline M. Grunenwald, Hannah K. Lin, Xinjie I. Yi, Devin L. Stauff, Eric P. Skaar
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
HitRS is a two-component system that responds to cell envelope damage in the bacterium Bacillus anthracis. Here, the authors identify an RNA-binding protein that regulates HitRS function by modulating the stability of the hitRS mRNA. In addition, the
Externí odkaz:
https://doaj.org/article/802b2c0c56704f229028f642e853b6b4
Autor:
Caroline M. Grunenwald, Erika Butler, Arno Wünschmann, Anibal G. Armien, Michelle Carstensen, Erik Hildebrand, Roger D. Moon, Richard W. Gerhold
Publikováno v:
Parasites & Vectors, Vol 11, Iss 1, Pp 1-11 (2018)
Abstract Background Moose (Alces alces) are a culturally and economically valued species in Minnesota. However, the moose population has experienced a sudden, marked decline in their range, including extirpation in the northwest and a 66% decline in
Externí odkaz:
https://doaj.org/article/2020e268659a46a69344fa2aaf369ca9
Autor:
Caroline M. Grunenwald, Jacob E. Choby, Lillian J. Juttukonda, William N. Beavers, Andy Weiss, Victor J. Torres, Eric P. Skaar
Publikováno v:
mBio, Vol 10, Iss 1 (2019)
ABSTRACT Manganese (Mn) is an essential micronutrient critical for the pathogenesis of Staphylococcus aureus, a significant cause of human morbidity and mortality. Paradoxically, excess Mn is toxic; therefore, maintenance of intracellular Mn homeosta
Externí odkaz:
https://doaj.org/article/60f1432fa64645f791d315ca384e153c
Staphylococcus aureus HemX Modulates Glutamyl-tRNA Reductase Abundance To Regulate Heme Biosynthesis
Autor:
Jacob E. Choby, Caroline M. Grunenwald, Arianna I. Celis, Svetlana Y. Gerdes, Jennifer L. DuBois, Eric P. Skaar
Publikováno v:
mBio, Vol 9, Iss 1 (2018)
ABSTRACT Staphylococcus aureus is responsible for a significant amount of devastating disease. Its ability to colonize the host and cause infection is supported by a variety of proteins that are dependent on the cofactor heme. Heme is a porphyrin use
Externí odkaz:
https://doaj.org/article/405059706deb49fc97647c9d061a40c4
Autor:
William J. Perry, Caroline M. Grunenwald, Raf Van de Plas, James C. Witten, Daniel R. Martin, Suneel S. Apte, James E. Cassat, Gösta B. Pettersson, Richard M. Caprioli, Eric P. Skaar, Jeffrey M. Spraggins
Publikováno v:
Cell Chemical Biology. 29(7)
Bacterial pathogens have evolved virulence factors to colonize, replicate, and disseminate within the vertebrate host. Although there is an expanding body of literature describing how bacterial pathogens regulate their virulence repertoire in respons
Autor:
Hualiang, Pi, Andy, Weiss, Clare L, Laut, Caroline M, Grunenwald, Hannah K, Lin, Xinjie I, Yi, Devin L, Stauff, Eric P, Skaar
Publikováno v:
Nature communications. 13(1)
HitRS is a two-component system that responds to cell envelope damage in the human pathogen Bacillus anthracis. Here we identify an RNA-binding protein, KrrA, that regulates HitRS function by modulating the stability of the hitRS mRNA. In addition to
Autor:
James E. Cassat, Jessica R. Sheldon, David E. Heinrichs, Richard M. Caprioli, Eric P. Skaar, Caroline M. Grunenwald, William J. Perry, Jeffrey M. Spraggins
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Siderophores, iron-scavenging small molecules, are fundamental to bacterial nutrient metal acquisition and enable pathogens to overcome challenges imposed by nutritional immunity. Multimodal imaging mass spectrometry allows visualization of host−pa
Autor:
McKenzie E. Daanen, Caroline M. Grunenwald, Jessica L. Kelliher, Warren E. Rose, Rhiannon R. Abrahams, John-Demian Sauer, Cassandra Lew
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 10, p e1009881 (2021)
PLoS Pathogens, Vol 17, Iss 10, p e1009881 (2021)
Pathogenic bacteria rely on protein phosphorylation to adapt quickly to stress, including that imposed by the host during infection. Penicillin-binding protein and serine/threonine-associated (PASTA) kinases are signal transduction systems that sense
Publikováno v:
Microbiology spectrum. 6(6)