Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Caroline M. Finn"'
Autor:
Caroline M. Finn, K. Kai McKinstry
Publikováno v:
Cells, Vol 13, Iss 7, p 639 (2024)
Current Influenza A virus (IAV) vaccines, which primarily aim to generate neutralizing antibodies against the major surface proteins of specific IAV strains predicted to circulate during the annual ‘flu’ season, are suboptimal and are characteriz
Externí odkaz:
https://doaj.org/article/df6f488f26534c9a9212970c15c74b1a
Autor:
Daniel Nierenberg, Orielyz Flores, David Fox, Yuen Yee Li Sip, Caroline M. Finn, Heba Ghozlan, Amanda Cox, Melanie Coathup, Karl Kai McKinstry, Lei Zhai, Annette R. Khaled
Publikováno v:
Biomimetics, Vol 7, Iss 4, p 219 (2022)
Optimizing the biological identity of nanoparticles (NPs) for efficient tumor uptake remains challenging. The controlled formation of a protein corona on NPs through protein absorption from biofluids could favor a biological identity that enables tum
Externí odkaz:
https://doaj.org/article/14948fc2c5f841329c43e0ba2b9cbce6
Publikováno v:
The Journal of Immunology. 210:1292-1304
It is generally accepted that influenza A virus (IAV) infection promotes a Th1-like CD4 T cell response and that this effector program underlies its protective impact. Canonical Th1 polarization requires cytokine-mediated activation of the transcript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::338aae90a5ef9f643cf1da326485739a
https://doi.org/10.4049/jimmunol.2200407
https://doi.org/10.4049/jimmunol.2200407
Autor:
Kunal Dhume, Caroline M. Finn, Priyadharshini Devarajan, Ayushi Singh, Joanne D. Tejero, Emily Prokop, Tara M. Strutt, Stewart Sell, Susan L. Swain, Karl Kai McKinstry
Publikováno v:
J Immunol
Optimal transcriptional programming needed for CD4 T cells to protect against influenza A virus (IAV) is unclear. Most IAV-primed CD4 T cells fit Th1 criteria. However, cells deficient for the Th1 “master regulator,” T-bet, although marked by red
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20f879c1d766d052f5c3f0a2db4be29c
https://doi.org/10.4049/jimmunol.2100801
https://doi.org/10.4049/jimmunol.2100801
Publikováno v:
The Journal of Immunology. 208:114.04-114.04
CD4+ tissue-resident memory (TRM) T cells act as sentinels at previous sites of infection and rapidly initiate protective inflammatory responses upon antigen re-encounter. Here, we tested if beyond local impacts in the lung, TRM responses lead to fas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32c2135109c001d0e68e87c8a280fab7
https://doi.org/10.4049/jimmunol.208.supp.114.04
https://doi.org/10.4049/jimmunol.208.supp.114.04
Publikováno v:
The Journal of Immunology. 206:65.06-65.06
Though bulk CD4 T cell responses against influenza A virus (IAV) are characterized as Th1, expression of the transcription factor T-bet (Tbx21), the ‘master regulator’ of Th1 fate, is not required for mice to clear IAV. While the Tbx21−/− CD4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59cc61e04bc13e8838070d5ec692acf0
https://doi.org/10.4049/jimmunol.206.supp.65.06
https://doi.org/10.4049/jimmunol.206.supp.65.06
Publikováno v:
The Journal of Immunology. 206:103.15-103.15
Most CD4 T cells responding to influenza A virus (IAV) fit prototypical Th1 criteria including high expression of the transcription factor T-bet, the Th1 ‘master regulator’, and strong IFNg production. Optimal Th1 development in vitro also requir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f643be7efffc2e500158704caa4956d2
https://doi.org/10.4049/jimmunol.206.supp.103.15
https://doi.org/10.4049/jimmunol.206.supp.103.15
Autor:
Karl Kai McKinstry, Caroline M Finn
Publikováno v:
The Journal of Immunology. 202:66.13-66.13
Tissue-resident memory (TRM) CD4 T cells are emerging as critical orchestrators of immunity but little is known about their response kinetics during secondary challenges. We recently developed an adoptive transfer model in which virus-specific CD4 TR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e7e5cefd9d5f0e7a345eb10b6d5b72e
https://doi.org/10.4049/jimmunol.202.supp.66.13
https://doi.org/10.4049/jimmunol.202.supp.66.13
Publikováno v:
Stress and Environmental Regulation of Gene Expression and Adaptation in Bacteria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04cd0bf0ef68ae3d206405d6f5f00a95
https://doi.org/10.1002/9781119004813.ch66
https://doi.org/10.1002/9781119004813.ch66
