Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Caroline M Tobin"'
Autor:
John M. Roe, Andrew M. Lovering, Caroline M Tobin, Anne A. Delsol, Alasdair P. MacGowan, Julie Sunderland
Publikováno v:
International Journal of Antimicrobial Agents. 24:511-514
A HPLC method is described for the simultaneous determination of avilamycin A and B in pig faeces, following extraction using acetonitrile and normal-phase solid phase extraction. The HPLC stationary phase was Kromosil 5 micro C-18 with a mobile phas
Autor:
Bill Hulme, Dinesh Saralaya, Daniel Peckham, Miles Denton, Steve Conway, Caroline M Tobin, Christine Etherington
Publikováno v:
Journal of Antimicrobial Chemotherapy. 53:325-328
Objectives Linezolid is a new oxazolidinone antibiotic with efficacy against a broad range of Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). In this study, we have determined the serum and sputum linezolid conce
Publikováno v:
Journal of Antimicrobial Chemotherapy. 47:271-275
The fluoroquinolones produce multiple photodegradation products. Little is known about these products, particularly whether any possess antimicrobial activity. To investigate this, we used the parallel-line bioassay to investigate discrepancies in zo
Autor:
Caroline M Tobin, John M. Roe, Julie Sunderland, Anne A. Delsol, Andrew M. Lovering, Alasdair P. MacGowan
Publikováno v:
Journal of Antimicrobial Chemotherapy. 52:135-137
An HPLC assay used to determine chlortetracycline (CTC) in pig faeces is reported. Prodigy ODS3 (4.6 x 150 mm) was used for the stationary phase, whereas the mobile phase comprised oxalic acid, sodium oxalate and sodium decane sulfonate (66%)--each o
Publikováno v:
The Journal of antimicrobial chemotherapy. 62(6)
Autor:
Ricardo Nalda-Molina, Steve Shaw, JA Cepeda, Alasdair P. MacGowan, Caroline M Tobin, Tony Whitehouse, C.C. Kibbler, Leon Aarons, Rob Shulman, Mervyn Singer, A Peter R Wilson
Publikováno v:
The Journal of antimicrobial chemotherapy. 55(3)
Objectives: To determine the pharmacokinetic characteristics of linezolid and teicoplanin in critically ill patients.Patients and methods: Serum was collected frequently during day 0 and then pre- and 1 h post-dose on days 1, 2, 3, 5, 7 and every thi
Autor:
Caroline M Tobin, Anne A. Delsol, Alasdair P. MacGowan, Andrew M. Lovering, John M. Roe, Julie Sunderland
Publikováno v:
International journal of antimicrobial agents. 23(4)
A reverse-phase HPLC assay is described for the simultaneous assay of enrofloxacin (ENR) and ciprofloxacin (CPX) in pig faeces. Extraction used dichloromethane, 2-propanol and 0.3M ortho-phosphoric acid (1:5:4 v/v/v). Separation was achieved using a
Publikováno v:
The Journal of antimicrobial chemotherapy. 52(1)
Objective To compare the accuracy and precision of commercial assay techniques in the measurement of gentamicin, tobramycin, amikacin, netilmicin and vancomycin in serum. Methods Data from the measurement of 40 external quality assessment samples fro
Autor:
G. Sweeney, J. M. Darville, Caroline M Tobin, A. P. MacGowan, John Fawcett Wilson, L. O. White, Alison H. Thomson
Publikováno v:
The Journal of antimicrobial chemotherapy. 50(5)
This study investigated vancomycin therapeutic drug monitoring (TDM) and issues related to patient management. Questionnaires were distributed to 310 participants in the UK National External Quality Assessment Scheme (NEQAS) for Antibiotic Assays. Th
Publikováno v:
Journal of Antimicrobial Chemotherapy. 51:1041-1042