Enhancing Clinical Information Display to Improve Patient Encounters: Human-Centered Design and Evaluation of the Parkinson Disease-BRIDGE Platform

Autor: Ethan G Brown, Erica Schleimer, Ian O Bledsoe, William Rowles, Nicolette A Miller, Stephan J Sanders, Katherine P Rankin, Jill L Ostrem, Caroline M Tanner, Riley Bove

Publikováno v: JMIR Human Factors, Vol 9, Iss 2, p e33967 (2022)

BackgroundPeople with Parkinson disease (PD) have a variety of complex medical problems that require detailed review at each clinical encounter for appropriate management. Care of other complex conditions has benefited from digital health solutions t

Externí odkaz: https://doaj.org/article/74c86bc52c514a0bb2c98bb75e92ad6e

Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.

Autor: Chuong B Do, Joyce Y Tung, Elizabeth Dorfman, Amy K Kiefer, Emily M Drabant, Uta Francke, Joanna L Mountain, Samuel M Goldman, Caroline M Tanner, J William Langston, Anne Wojcicki, Nicholas Eriksson

Publikováno v: PLoS Genetics, Vol 7, Iss 6, p e1002141 (2011)

Although the causes of Parkinson's disease (PD) are thought to be primarily environmental, recent studies suggest that a number of genes influence susceptibility. Using targeted case recruitment and online survey instruments, we conducted the largest

Externí odkaz: https://doaj.org/article/66e71c88538947f0b1affaba60c8bde2

Parkinson’s Progression Markers Initiative: A Milestone-Based Strategy to Monitor PD Progression

Autor: Michael C. Brumm, Andrew Siderowf, Tanya Simuni, Elliot Burghardt, Seung Ho Choi, Chelsea Caspell-Garcia, Lana M. Chahine, Brit Mollenhauer, Tatiana Foroud, Douglas Galasko, Kalpana Merchant, Vanessa Arnedo, Samantha J. Hutten, Alyssa N. O’Grady, Kathleen L. Poston, Caroline M. Tanner, Daniel Weintraub, Karl Kieburtz, Kenneth Marek, Christopher S. Coffey

BackgroundIdentifying a meaningful progression metric for Parkinson’s disease (PD) that reflects heterogeneity remains a challenge.ObjectiveTo assess the frequency and baseline predictors of progression to clinically relevant motor and non-motor PD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6d8adbd7a834f151007c6f2ea33c410e
https://doi.org/10.1101/2023.05.23.23290344

Genome-wide association study identifies a new susceptibility locus inPLA2G4Cfor Multiple System Atrophy

Autor: Yasuo Nakahara, Jun Mitsui, Hidetoshi Date, Kristine Joyce Porto, Yasuhiro Hayashi, Atsushi Yamashita, Yoshio Kusakabe, Takashi Matsukawa, Hiroyuki Ishiura, Tsutomu Yasuda, Atsushi Iwata, Jun Goto, Yaeko Ichikawa, Yoshio Momose, Yuji Takahashi, Tatsushi Toda, Rikifumi Ohta, Jun Yoshimura, Shinichi Morishita, Emil K Gustavsson, Darren Christy, Melissa Maczis, Matthew J. Farrer, Han-Joon Kim, Sung-Sup Park, Beomseok Jeon, Jin Zhang, Weihong Gu, Sonja W. Scholz, Andrew B. Singleton, Henry Houlden, Ichiro Yabe, Hidenao Sasaki, Masaaki Matsushima, Hiroshi Takashima, Akio Kikuchi, Masashi Aoki, Kenju Hara, Akiyoshi Kakita, Mitsunori Yamada, Hitoshi Takahashi, Osamu Onodera, Masatoyo Nishizawa, Hirohisa Watanabe, Mizuki Ito, Gen Sobue, Kinya Ishikawa, Hidehiro Mizusawa, Kazuaki Kanai, Satoshi Kuwabara, Kimihito Arai, Shigeru Koyano, Yoshiyuki Kuroiwa, Kazuko Hasegawa, Tatsuhiko Yuasa, Kenichi Yasui, Kenji Nakashima, Hijiri Ito, Yuishin Izumi, Ryuji Kaji, Takeo Kato, Susumu Kusunoki, Yasushi Osaki, Masahiro Horiuchi, Ken Yamamoto, Mihoko Shimada, Taku Miyagawa, Yosuke Kawai, Nao Nishida, Katsushi Tokunaga, Alexandra Dürr, Alexis Brice, Alessandro Filla, Thomas Klockgether, Ullrich Wüllner, Caroline M. Tanner, Walter A. Kukull, Virginia M.-Y. Lee, Eliezer Masliah, Phillip A. Low, Paola Sandroni, Laurie Ozelius, Tatiana Foroud, Shoji Tsuji

To elucidate the molecular basis of multiple system atrophy (MSA), a neurodegenerative disease, we conducted a genome-wide association study (GWAS) in a Japanese MSA case/control series followed by replication studies in Japanese, Korean, Chinese, Eu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c0ca23eb995d2b34d1429411448aeb26
https://doi.org/10.1101/2023.05.02.23289328

Impact of possible tardive dyskinesia on physical wellness and social functioning: results from the real-world RE-KINECT study

Autor: Caroline M. Tanner, Stanley N. Caroff, Andrew J. Cutler, William R. Lenderking, Huda Shalhoub, Véronique Pagé, Ericha G. Franey, Michael Serbin, Chuck Yonan

Publikováno v: Journal of patient-reported outcomes, vol 7, iss 1

Abstract Background Tardive dyskinesia (TD) is a persistent and potentially disabling movement disorder associated with antipsychotic use. Data from RE-KINECT, a real-world study of antipsychotic-treated outpatients, were analyzed to assess the effec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e55b75080fad3a2e1c70193bb0577ebf
https://escholarship.org/uc/item/5688d5sp