FGF21 regulates hepatic metabolic pathways to improve steatosis and inflammation

Autor: Helle Keinicke, Gao Sun, Caroline M Junker Mentzel, Merete Fredholm, Linu Mary John, Birgitte Andersen, Kirsten Raun, Marina Kjaergaard

Publikováno v: Endocrine Connections, Vol 9, Iss 8, Pp 755-768 (2020)

The prevalence of non-alcoholic fatty liver disease (NAFLD) has increased dramatically worldwide and, subsequently, also the risk of developing non-alcoholic steatohepatitis (NASH), hepatic fibrosis, cirrhosis and cancer. Today, weight lo ss is the o

Externí odkaz: https://doaj.org/article/e68e13f481f74afe897403913b097076

Joint Profiling of miRNAs and mRNAs Reveals miRNA Mediated Gene Regulation in the Göttingen Minipig Obesity Model.

Autor: Caroline M Junker Mentzel, Ferhat Alkan, Helle Keinicke, Mette J Jacobsen, Jan Gorodkin, Merete Fredholm, Susanna Cirera

Publikováno v: PLoS ONE, Vol 11, Iss 11, p e0167285 (2016)

Obesity and its comorbidities are an increasing challenge for both affected individuals and health care systems, worldwide. In obese individuals, perturbation of expression of both protein-coding genes and microRNAs (miRNA) are seen in obesity-releva

Externí odkaz: https://doaj.org/article/28b2ef31f04a4270b3a85ea2033c7c65

Fecal virome transfer improves proliferation of commensal gut Akkermansia muciniphila and unexpectedly enhances the fertility rate in laboratory mice

Autor: Torben Sølbeck Rasmussen, Caroline M. Junker Mentzel, Malene Refslund Danielsen, Rasmus Riemer Jakobsen, Line Sidsel Fisker Zachariassen, Josue Leonardo Castro Mejia, Anders Brunse, Lars Hestbjerg Hansen, Camilla Hartmann Friis Hansen, Axel Kornerup Hansen, Dennis Sandris Nielsen

Publikováno v: Rasmussen, T S, Mentzel, C M J, Danielsen, M R, Jakobsen, R R, Zachariassen, L S F, Castro Mejia, J L, Brunse, A, Hansen, L H, Hansen, C H F, Hansen, A K & Nielsen, D S 2023, ' Fecal virome transfer improves proliferation of commensal gut Akkermansia muciniphila and unexpectedly enhances the fertility rate in laboratory mice ', Gut Microbes, vol. 15, no. 1, 2208504 . https://doi.org/10.1080/19490976.2023.2208504

Probiotics are intended to improve gastrointestinal health when consumed. However, the probiotics marketed today only colonize the densely populated gut to a limited extent. Bacteriophages comprise the majority of viruses in the human gut virome and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c15989a786a3c5cca020e5f92956e1d
https://doi.org/10.1080/19490976.2023.2208504

FGF21 regulates hepatic metabolic pathways to improve steatosis and inflammation

Autor: Kirsten Raun, Helle Keinicke, Gao Sun, Birgitte Andersen, Merete Fredholm, Linu M. John, Marina Kjaergaard, Caroline M. Junker Mentzel

Publikováno v: Endocrine Connections, Vol 9, Iss 8, Pp 755-768 (2020)
Endocrine Connections
Keinicke, H, Sun, G, Mentzel, C M J, Fredholm, M, John, L M, Andersen, B, Raun, K & Kjaergaard, M 2020, ' Fgf21 regulates hepatic metabolic pathways to improve steatosis and inflammation ', Endocrine Connections, vol. 9, no. 8, pp. 755-768 . https://doi.org/10.1530/EC-20-0152

The prevalence of non-alcoholic fatty liver disease (NAFLD) has increased dramatically worldwide and, subsequently, also the risk of developing non-alcoholic steatohepatitis (NASH), hepatic fibrosis, cirrhosis and cancer. Today, weight loss is the on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b1b8aa4c65fcc8781460b252b5636c7
https://ec.bioscientifica.com/view/journals/ec/9/8/EC-20-0152.xml

Faecal virome transplantation decrease symptoms of type-2-diabetes and obesity in a murine model

Autor: Torben Rasmussen, Axel Kornerup Hansen, Simone Zuffa, Witold Kot, Dennis Sandris Nielsen, Finn K. Vogensen, Caroline M. Junker Mentzel, Jonathan R. Swann, Lars Hestbjerg Hansen, Josué L. Castro-Mejía

ObjectiveDevelopment of obesity and type-2-diabetes (T2D) are associated with gut microbiota (GM) changes. The gut viral community is predominated by bacteriophages (phages), which are viruses that attack bacteria in a host-specific manner. As a proo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6277908e4c4aedd10541546fd07a51c