Zobrazeno 1 - 10
of 171
pro vyhledávání: '"Caroline Lynn Kamerlin"'
Autor:
Marina Corbella, Joe Bravo, Andrey O. Demkiv, Ana Rita Calixto, Kitty Sompiyachoke, Celine Bergonzi, Alfie-Louise R. Brownless, Mikael H. Elias, Shina Caroline Lynn Kamerlin
Publikováno v:
JACS Au, Vol 4, Iss 9, Pp 3519-3536 (2024)
Externí odkaz:
https://doaj.org/article/fa4005343c2f4dc9ab8bb0acc449e9ac
Autor:
Enrico Hupfeld, Sandra Schlee, Jan Philip Wurm, Chitra Rajendran, Dariia Yehorova, Eva Vos, Dinesh Ravindra Raju, Shina Caroline Lynn Kamerlin, Remco Sprangers, Reinhard Sterner
Publikováno v:
JACS Au, Vol 4, Iss 8, Pp 3258-3276 (2024)
Externí odkaz:
https://doaj.org/article/d93e4f16987b4d8c80cb7c4b1b0c6508
Publikováno v:
ACS Central Science, Vol 8, Iss 8, Pp 1040-1042 (2022)
Externí odkaz:
https://doaj.org/article/bf115d35a69e42a19e416120c64e0808
Publikováno v:
ACS Omega, Vol 5, Iss 9, Pp 4380-4385 (2020)
Externí odkaz:
https://doaj.org/article/28b11df047fd42178402787a3f17259e
Autor:
Vimal Parkash, Yashraj Kulkarni, Josy ter Beek, Polina V. Shcherbakova, Shina Caroline Lynn Kamerlin, Erik Johansson
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Mutations in the human POLE gene are associated with tumours with high mutational loads. Here the authors provide a structural rationale for the mutagenic activity of the cancer-associated DNA polymerase ε P286R variant.
Externí odkaz:
https://doaj.org/article/347e31414f014ab19733e8e7a0a88110
Autor:
Philippe B. Wilson, Chiemela S. Odoemelam, Elena Hunter, Zeeshan Ahmad, Caroline Lynn Kamerlin, Samuel White
Publikováno v:
Current Pharmaceutical Design. 28:3637-3648
Aim: The cytochrome P450 enzymes play a significant role in regulating cellular and physiological processes by activating endogenous compounds. They also play an essential role in the detoxification process of xenobiotics. Flavonoids belong to a clas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::921caf83f19933bbda18007f8887e658
https://doi.org/10.2174/1381612829666221121151713
https://doi.org/10.2174/1381612829666221121151713
Autor:
Aleksandra Maršavelski, Dušan Petrović, Paul Bauer, Robert Vianello, Shina Caroline Lynn Kamerlin
Publikováno v:
ACS Omega, Vol 3, Iss 4, Pp 3665-3674 (2018)
Externí odkaz:
https://doaj.org/article/40c02973e51b4be0bc790d820cf4c579
Autor:
Beat Anton Amrein, Fabian Steffen-Munsberg, Ireneusz Szeler, Miha Purg, Yashraj Kulkarni, Shina Caroline Lynn Kamerlin
Publikováno v:
IUCrJ, Vol 4, Iss 1, Pp 50-64 (2017)
The tremendous interest in enzymes as biocatalysts has led to extensive work in enzyme engineering, as well as associated methodology development. Here, a new framework for computer-aided directed evolution of enzymes (CADEE) is presented which allow
Externí odkaz:
https://doaj.org/article/1d624775a53c4aa78b73074d83ceb136
Publikováno v:
EMBO reports.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c4eaaae2be3a56fe485f0c53ce61c43
https://doi.org/10.15252/embr.202357409
https://doi.org/10.15252/embr.202357409
Simulation datasets of proteins (e.g., those generated by molecular dynamics simulations) are filled with information about how the non-covalent interaction network within a protein regulates the conformation and thus function of said protein. Most p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::267bb694a8cd30ae53bccf4770218b32
https://doi.org/10.26434/chemrxiv-2023-d0h8h
https://doi.org/10.26434/chemrxiv-2023-d0h8h
