Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Caroline Lassnig"'
Autor:
Ulrike Schmidt, Betül Uluca, Iva Vokic, Barizah Malik, Thomas Kolbe, Caroline Lassnig, Martin Holcmann, Veronica Moreno-Viedma, Bernhard Robl, Carina Mühlberger, Dagmar Gotthardt, Maria Sibilia, Thomas Rülicke, Mathias Müller, Agnes Csiszar
Publikováno v:
PLoS ONE, Vol 18, Iss 9, p e0286256 (2023)
FAM3C/ILEI is an important factor in epithelial-to-mesenchymal transition (EMT) induction, tumor progression and metastasis. Overexpressed in many cancers, elevated ILEI levels and secretion correlate with poor patient survival. Although ILEI's causa
Externí odkaz:
https://doaj.org/article/994b8dfe26b74aa0b5ce6ad114d089ef
Autor:
Katharina Woess, Sabine Macho-Maschler, Dorette S. van Ingen Schenau, Miriam Butler, Caroline Lassnig, Daniel Valcanover, Andrea Poelzl, Katrin Meissl, Barbara Maurer, Tania Brandstoetter, Claus Vogl, Anna Koren, Stefan Kubicek, Anna Orlova, Richard Moriggl, Birgit Strobl, Veronika Sexl, Frank N. van Leeuwen, Roland P. Kuiper, Mathias Mueller
Publikováno v:
Haematologica, Vol 108, Iss 4 (2022)
Tyrosine kinase 2 (TYK2) is a member of the Janus kinase/signal transducer and activator of transcription pathway, which is central in cytokine signaling. Previously, germline TYK2 mutations have been described in two patients developing de novo T-ce
Externí odkaz:
https://doaj.org/article/16495fc0f1644407926d2399569c73ec
Autor:
Duygu Demiroz, Ekaterini Platanitis, Michael Bryant, Philipp Fischer, Michaela Prchal-Murphy, Alexander Lercher, Caroline Lassnig, Manuela Baccarini, Mathias Müller, Andreas Bergthaler, Veronika Sexl, Marlies Dolezal, Thomas Decker
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009697 (2021)
Listeria monocytogenes (L. monocytogenes) is a food-borne bacterial pathogen. Innate immunity to L. monocytogenes is profoundly affected by type I interferons (IFN-I). Here we investigated host metabolism in L. monocytogenes-infected mice and its pot
Externí odkaz:
https://doaj.org/article/beb651fb415042b485b48a268a33620a
Publikováno v:
Animals, Vol 12, Iss 16, p 2141 (2022)
Ambient temperature is an important non-biotic environmental factor influencing immunological and oncological parameters in laboratory mice. It is under discussion which temperature is more appropriate and whether the commonly used room temperature i
Externí odkaz:
https://doaj.org/article/a1534fcbc32944a1b30e89b48953b7be
Autor:
Katrin Meissl, Natalija Simonović, Lena Amenitsch, Agnieszka Witalisz-Siepracka, Klara Klein, Caroline Lassnig, Ana Puga, Claus Vogl, Andrea Poelzl, Markus Bosmann, Alexander Dohnal, Veronika Sexl, Mathias Müller, Birgit Strobl
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Natural killer (NK) cells are important components of the innate immune defense against infections and cancers. Signal transducer and activator of transcription 1 (STAT1) is a transcription factor that is essential for NK cell maturation and NK cell-
Externí odkaz:
https://doaj.org/article/66b5c411e76242849b6bb7f69d378e49
Autor:
Eva Harter, Caroline Lassnig, Eva Maria Wagner, Andreas Zaiser, Martin Wagner, Kathrin Rychli
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
The pathogenicity of the human foodborne pathogen Listeria monocytogenes relies on virulence factors such as internalins. In 2009/2010 two L. monocytogenes strains were responsible for a serious listeriosis outbreak in Austria, Germany, and the Czech
Externí odkaz:
https://doaj.org/article/504fda4873694e96b99ddc2bc0df50bf
Autor:
Daniel Szappanos, Roland Tschismarov, Thomas Perlot, Sandra Westermayer, Katrin Fischer, Ekaterini Platanitis, Fabian Kallinger, Maria Novatchkova, Caroline Lassnig, Mathias Müller, Veronika Sexl, Keiryn L Bennett, Michelle Foong-Sobis, Josef M Penninger, Thomas Decker
Publikováno v:
PLoS Pathogens, Vol 14, Iss 11, p e1007397 (2018)
DExD/H box RNA helicases, such as the RIG-I-like receptors (RLR), are important components of the innate immune system. Here we demonstrate a pivotal and sex-specific role for the heterosomal isoforms of the DEAD box RNA helicase DDX3 in the immune s
Externí odkaz:
https://doaj.org/article/cc39cd3dbcd34a1a93d9551afd1f3bfa
Autor:
Tom Grunert, Avril Monahan, Caroline Lassnig, Claus Vogl, Mathias Müller, Monika Ehling-Schulz
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115959 (2014)
Bacterial pathogens are known for their wide range of strategies to specifically adapt to host environments and infection sites. An in-depth understanding of these adaptation mechanisms is crucial for the development of effective therapeutics and new
Externí odkaz:
https://doaj.org/article/ce4ded49a97746e5ade71188885e4331
Autor:
Nicole R Leitner, Caroline Lassnig, Rita Rom, Susanne Heider, Zsuzsanna Bago-Horvath, Robert Eferl, Simone Müller, Thomas Kolbe, Lukas Kenner, Thomas Rülicke, Birgit Strobl, Mathias Müller
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86608 (2014)
Signal transducer and activator of transcription (STAT) 1 is a key player in interferon (IFN) signaling, essential in mediating host defense against viruses and other pathogens. STAT1 levels are tightly regulated and loss- or gain-of-function mutatio
Externí odkaz:
https://doaj.org/article/6fd3c0b5cb514c1389f90ac6c5a95fc6
Autor:
Afitap Derya Köprülü, Renate Kastner, Sebastian Wienerroither, Caroline Lassnig, Eva Maria Putz, Olivia Majer, Benjamin Reutterer, Veronika Sexl, Karl Kuchler, Mathias Müller, Thomas Decker, Wilfried Ellmeier
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e60476 (2013)
In this study we investigated the role of Bruton's tyrosine kinase (Btk) in the immune response to the Gram-positive intracellular bacterium Listeria monocytogenes (Lm). In response to Lm infection, Btk was activated in bone marrow-derived macrophage
Externí odkaz:
https://doaj.org/article/58939eec8e2f40328ff293b57e933d81