Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Caroline L Hoad"'
Autor:
Khaled Heissam, Nichola Abrehart, Caroline L Hoad, Jeff Wright, Alex Menys, Kathryn Murray, Paul M Glover, Geoffrey Hebbard, Penny A Gowland, Jason Baker, William L Hasler, Robin C Spiller, Maura Corsetti, James G Brasseur, Bart Hens, Kerby Shedden, Joseph Dickens, Deanna M Mudie, Greg E Amidon, Gordon L Amidon, Luca Marciani
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0241441 (2020)
ObjectiveThe gastrointestinal environment in which drug products need to disintegrate before the drug can dissolve and be absorbed has not been studied in detail due to limitations, especially invasiveness of existing techniques. Minimal in vivo data
Externí odkaz:
https://doaj.org/article/8b870100c3494f05b33becca50d1d77a
Autor:
Kathryn A Murray, Caroline L Hoad, Jill Garratt, Mehri Kaviani, Luca Marciani, Jan K Smith, Britta Siegmund, Penny A Gowland, David J Humes, Robin C Spiller
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216528 (2019)
BackgroundComplications of diverticular disease are increasingly common, possibly linked to increasing obesity. Visceral fat could contribute to the development of symptomatic diverticular disease through its pro-inflammatory effects.ObjectiveThe stu
Externí odkaz:
https://doaj.org/article/f618c143a9824553bb0ae4fb1992d402
Autor:
Tim J Sloan, Jonna Jalanka, Giles A D Major, Shanthi Krishnasamy, Sue Pritchard, Salah Abdelrazig, Katri Korpela, Gulzar Singh, Claire Mulvenna, Caroline L Hoad, Luca Marciani, David A Barrett, Miranda C E Lomer, Willem M de Vos, Penny A Gowland, Robin C Spiller
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0201410 (2018)
BACKGROUND & AIMS:Ingestion of poorly digested, fermentable carbohydrates (fermentable oligo-, di-, mono-saccharides and polyols; FODMAPs) have been implicated in exacerbating intestinal symptoms and the reduction of intake with symptom alleviation.
Externí odkaz:
https://doaj.org/article/baf301fd890543c188f98ec62f70859a
Autor:
Faiz Alqarni, Tejal Akbar, Hala Fatani, Soma Kumasaka, Caroline L. Hoad, Robin C. Spiller, Moira A. Taylor, Luca Marciani
Publikováno v:
Diagnostics, Vol 14, Iss 19, p 2190 (2024)
Purpose: Knowledge of the length of the colon is relevant to understanding physiological and pathological function. It also has implications for diagnostic and clinical interventions, as well as for the design of delayed-release drug formulations and
Externí odkaz:
https://doaj.org/article/4ffd25e0aac54d2582f70a950286606b
Autor:
Fahad Almutairi, Jaber Alyami, Susan Pritchard, Wala Alsharef, Robin C. Spiller, Penny A. Gowland, Moira A. Taylor, Luca Marciani, Caroline L. Hoad
Publikováno v:
Clinical Nutrition Open Science, Vol 51, Iss , Pp 35-43 (2023)
Summary: The presence of a ‘magenstrasse’, a central ‘stomach road’ for flow and mixing of foods and drinks in the stomach had been predicted from hydrodynamic modelling. Here a magnetic resonance imaging (MRI) tagging technique was used to g
Externí odkaz:
https://doaj.org/article/f98d9193e65041188205539a1800d1a3
Autor:
Hayfa Sharif, Caroline L. Hoad, Nichola Abrehart, Penny A. Gowland, Robin C. Spiller, Sian Kirkham, Sabarinathan Loganathan, Michalis Papadopoulos, Marc A. Benninga, David Devadason, Luca Marciani
Publikováno v:
PLoS ONE, Vol 19, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/639480a865f9413bb01271d29b17784f
Autor:
Amber M. Milan, Matthew P. G. Barnett, Warren C. McNabb, Nicole C. Roy, Schynell Coutinho, Caroline L. Hoad, Luca Marciani, Samson Nivins, Hayfa Sharif, Timothy R. Angeli-Gordon, Peng Du, Armen A. Gharibans, Greg O’Grady, Pankaja Sharma, Aahana Shrestha, Richard F. Mithen
Publikováno v:
Medical Sciences Forum, Vol 18, Iss 1, p 8 (2023)
Milk structural assemblies (e.g., casein micelles) occur naturally and can be altered during processing, and this may influence the milk’s nutritional properties. Heat treatment of dairy ensures microbiological safety and extends shelf-life. Both p
Externí odkaz:
https://doaj.org/article/d450a4aa11194b28bacb48adc286390f
Autor:
Michael Schütt, Connor O’Farrell, Konstantinos Stamatopoulos, Caroline L. Hoad, Luca Marciani, Sarah Sulaiman, Mark J. H. Simmons, Hannah K. Batchelor, Alessio Alexiadis
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1402 (2022)
In the original publication [...]
Externí odkaz:
https://doaj.org/article/a147ba1016604bc4b9fe7911f6d82691
Autor:
Abdulsalam I. Aliyu, Aline Nixon, Caroline L. Hoad, Luca Marciani, Maura Corsetti, Guruprasad P. Aithal, Sally M. Cordon, Ian A. Macdonald, Maha H. Alhussain, Hiroaki Inoue, Masahiko Yamada, Moira A. Taylor
Publikováno v:
British Journal of Nutrition. :1-13
Inclusion in nasogastric tube feeds (NGTF) of acid-sensitive, seaweed-derived alginate, expected to form a reversible gel in the stomach, may create a more normal intragastric state and modified gastrointestinal responses. This may ameliorate NGTF-as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35fdcb22501b569d8d9726e0b4b434ad
https://doi.org/10.1017/s0007114523000302
https://doi.org/10.1017/s0007114523000302
Autor:
Michael Schütt, Connor O’Farrell, Konstantinos Stamatopoulos, Caroline L. Hoad, Luca Marciani, Sarah Sulaiman, Mark J. H. Simmons, Hannah K. Batchelor, Alessio Alexiadis
Publikováno v:
Pharmaceutics, Vol 14, Iss 1, p 184 (2022)
The performance of solid oral dosage forms targeting the colon is typically evaluated using standardised pharmacopeial dissolution apparatuses. However, these fail to replicate colonic hydrodynamics. This study develops a digital twin of the Dynamic
Externí odkaz:
https://doaj.org/article/7613cdd0ba5543b0814e9a526b2a501f