Zobrazeno 1 - 10
of 209
pro vyhledávání: '"Caroline L Hoad"'
Autor:
Faiz Alqarni, Tejal Akbar, Hala Fatani, Soma Kumasaka, Caroline L. Hoad, Robin C. Spiller, Moira A. Taylor, Luca Marciani
Publikováno v:
Diagnostics, Vol 14, Iss 19, p 2190 (2024)
Purpose: Knowledge of the length of the colon is relevant to understanding physiological and pathological function. It also has implications for diagnostic and clinical interventions, as well as for the design of delayed-release drug formulations and
Externí odkaz:
https://doaj.org/article/4ffd25e0aac54d2582f70a950286606b
Autor:
Fahad Almutairi, Jaber Alyami, Susan Pritchard, Wala Alsharef, Robin C. Spiller, Penny A. Gowland, Moira A. Taylor, Luca Marciani, Caroline L. Hoad
Publikováno v:
Clinical Nutrition Open Science, Vol 51, Iss , Pp 35-43 (2023)
Summary: The presence of a ‘magenstrasse’, a central ‘stomach road’ for flow and mixing of foods and drinks in the stomach had been predicted from hydrodynamic modelling. Here a magnetic resonance imaging (MRI) tagging technique was used to g
Externí odkaz:
https://doaj.org/article/f98d9193e65041188205539a1800d1a3
Autor:
Hayfa Sharif, Caroline L. Hoad, Nichola Abrehart, Penny A. Gowland, Robin C. Spiller, Sian Kirkham, Sabarinathan Loganathan, Michalis Papadopoulos, Marc A. Benninga, David Devadason, Luca Marciani
Publikováno v:
PLoS ONE, Vol 19, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/639480a865f9413bb01271d29b17784f
Autor:
Amber M. Milan, Matthew P. G. Barnett, Warren C. McNabb, Nicole C. Roy, Schynell Coutinho, Caroline L. Hoad, Luca Marciani, Samson Nivins, Hayfa Sharif, Timothy R. Angeli-Gordon, Peng Du, Armen A. Gharibans, Greg O’Grady, Pankaja Sharma, Aahana Shrestha, Richard F. Mithen
Publikováno v:
Medical Sciences Forum, Vol 18, Iss 1, p 8 (2023)
Milk structural assemblies (e.g., casein micelles) occur naturally and can be altered during processing, and this may influence the milk’s nutritional properties. Heat treatment of dairy ensures microbiological safety and extends shelf-life. Both p
Externí odkaz:
https://doaj.org/article/d450a4aa11194b28bacb48adc286390f
Autor:
Michael Schütt, Connor O’Farrell, Konstantinos Stamatopoulos, Caroline L. Hoad, Luca Marciani, Sarah Sulaiman, Mark J. H. Simmons, Hannah K. Batchelor, Alessio Alexiadis
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1402 (2022)
In the original publication [...]
Externí odkaz:
https://doaj.org/article/a147ba1016604bc4b9fe7911f6d82691
Autor:
Abdulsalam I. Aliyu, Aline Nixon, Caroline L. Hoad, Luca Marciani, Maura Corsetti, Guruprasad P. Aithal, Sally M. Cordon, Ian A. Macdonald, Maha H. Alhussain, Hiroaki Inoue, Masahiko Yamada, Moira A. Taylor
Publikováno v:
British Journal of Nutrition. :1-13
Inclusion in nasogastric tube feeds (NGTF) of acid-sensitive, seaweed-derived alginate, expected to form a reversible gel in the stomach, may create a more normal intragastric state and modified gastrointestinal responses. This may ameliorate NGTF-as
Autor:
Khaled Heissam, Nichola Abrehart, Caroline L Hoad, Jeff Wright, Alex Menys, Kathryn Murray, Paul M Glover, Geoffrey Hebbard, Penny A Gowland, Jason Baker, William L Hasler, Robin C Spiller, Maura Corsetti, James G Brasseur, Bart Hens, Kerby Shedden, Joseph Dickens, Deanna M Mudie, Greg E Amidon, Gordon L Amidon, Luca Marciani
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0241441 (2020)
ObjectiveThe gastrointestinal environment in which drug products need to disintegrate before the drug can dissolve and be absorbed has not been studied in detail due to limitations, especially invasiveness of existing techniques. Minimal in vivo data
Externí odkaz:
https://doaj.org/article/8b870100c3494f05b33becca50d1d77a
Autor:
Michael Schütt, Connor O’Farrell, Konstantinos Stamatopoulos, Caroline L. Hoad, Luca Marciani, Sarah Sulaiman, Mark J. H. Simmons, Hannah K. Batchelor, Alessio Alexiadis
Publikováno v:
Pharmaceutics, Vol 14, Iss 1, p 184 (2022)
The performance of solid oral dosage forms targeting the colon is typically evaluated using standardised pharmacopeial dissolution apparatuses. However, these fail to replicate colonic hydrodynamics. This study develops a digital twin of the Dynamic
Externí odkaz:
https://doaj.org/article/7613cdd0ba5543b0814e9a526b2a501f
Autor:
Sarah Sulaiman, Pavel Gershkovich, Caroline L. Hoad, Matthew Calladine, Robin C. Spiller, Snow Stolnik, Luca Marciani
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 270 (2022)
Oral specially coated formulations have the potential to improve treatment outcomes of a range of diseases in distal intestinal tract whilst limiting systemic drug absorption and adverse effects. Their development is challenging, partly because of li
Externí odkaz:
https://doaj.org/article/f68c840370fa4199bda136de72ef4c95
Autor:
Ali Alyami, Caroline L. Hoad, Christopher Tench, Uday Bannur, Christopher Clarke, Khalid Latief, Konstantinos Argyriou, Alan Lobo, Philip Lung, Rachel Baldwin-Cleland, Kapil Sahnan, Ailsa Hart, Jimmy K. Limdi, John Mclaughlin, David Atkinson, Geoffrey J. M. Parker, James P. B. O’Connor, Ross A. Little, Penny A. Gowland, Gordon W. Moran
Publikováno v:
Diagnostics, Vol 11, Iss 11, p 2135 (2021)
Perianal Crohn’s Disease (pCD) is a common manifestation of Crohn’s Disease. Absence of reliable disease measures makes disease monitoring unreliable. Qualitative MRI has been increasingly used for diagnosing and monitoring pCD and has shown pote
Externí odkaz:
https://doaj.org/article/74ba319f25de4b3fae15fcb087fe6c40