Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Caroline Johnson-Leger"'
Autor:
Beat A. Imhof, Caroline Johnson-Leger
Publikováno v:
Cell and Tissue Research, Vol. 314, No 1 (2003) pp. 93-105
During an inflammatory response, changes in the adhesive properties of the endothelium occur that enable normally non-adherent blood-borne leukocytes to adhere and subsequently to traverse the endothelium through small gaps at inter-cellular junction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6af50e0a766161c16fc33567a087b10
https://doi.org/10.1007/s00441-003-0775-4
https://doi.org/10.1007/s00441-003-0775-4
Autor:
Chrystelle Lamagna, Michel Aurrand-Lions, Toru Kita, Harunobu Ozaki, Beat A. Imhof, Caroline Johnson-Leger
Publikováno v:
Cells Tissues Organs, Vol. 172, No 3 (2002) pp. 152-160
Similar to epithelia, endothelial cells are linked to each other via intercellular junctional complexes including gap junctions, adherens junctions and tight junctions. While polarized epithelial cells show a high degree of spatial sorting of junctio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77223c8797ddf199835fa9c0075a6a08
https://doi.org/10.1159/000066967
https://doi.org/10.1159/000066967
Autor:
Louis Du Pasquier, Michel Aurrand-Lions, Beat A. Imhof, Cindy W.Y. Wong, Caroline Johnson-Leger
Publikováno v:
Blood, Vol. 98, No 13 (2001) pp. 3699-3707
Endothelial cells are linked to each other through intercellular junctional complexes that regulate the barrier and fence function of the vascular wall. The nature of these intercellular contacts varies with the need for permeability: For example, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91656b928f8491a000d19f2f0caa264d
https://doi.org/10.1182/blood.v98.13.3699
https://doi.org/10.1182/blood.v98.13.3699
Publikováno v:
Nature Immunology, Vol. 3, No 2 (2002) pp. 116-118
Leukocyte arrest on inflamed endothelium constitutes only the first phase of their recruitment into the tissues. New data points to the roles played by JAM-1 and CD99 in leukocyte passage through the barrier posed by the vascular endothelium during i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74ebdafdcf3ecb004eeb410dd58d1234
https://doi.org/10.1038/ni0202-116
https://doi.org/10.1038/ni0202-116
Autor:
Catherine Jorand-Lebrun, Vittoria Ardissone, Dominique Perrin, Chiara Ferrandi, Agnes Bombrun, Linfeng Chen, Corine Gillieron, Pierre Juillard, Margaret A. Shipp, Serge Halazy, Patrick Gerber, Fiona J. Pixley, Caroline Johnson-Leger, Christian Rommel, Rob Hooft van Huijsduijnen, Rosanna Pescini Gobert, Pierre-Alain Vitte, Cedric Szyndralewiez, Montserrat Camps, Dominique Swinnen, Monique van den Eijnden
We describe novel, cell-permeable, and bioavailable salicylic acid derivatives that are potent and selective inhibitors of GLEPP1/protein-tyrosine phosphatase φ. Two previously described GLEPP1 substrates, paxillin and Syk, are both required for cyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1393fa2d5f75599b740ee084d01e4963
https://europepmc.org/articles/PMC2670144/
https://europepmc.org/articles/PMC2670144/
Autor:
Harald S. Haugen, Monica Anderson, Katarzyna Warszawska, Sandra Philipp, Kim Waggie, Ellen Witte, Wolfram Sterry, Katrin Witte, Wenfeng Xu, Hans-Dieter Volk, Elmar vom Baur, Kerstin Wolk, Robert Sabat, Caroline Johnson-Leger
Publikováno v:
Journal of molecular medicine (Berlin, Germany). 87(5)
Psoriasis is a common chronic skin disease with a largely unknown pathogenesis. We demonstrate here that transgenic over-expression of interleukin (IL)-22 in mice resulted in neonatal mortality and psoriasis-like skin alterations including acanthosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::633c9a958fdbaa5573f571e9e5d92ebe
https://pubmed.ncbi.nlm.nih.gov/19330474
https://pubmed.ncbi.nlm.nih.gov/19330474
Publikováno v:
International immunology, Vol. 20, No 2 (2008) pp. 247-57
One of the key components of the innate immune response is the recognition of microbial products such as LPS by Toll-like receptors on monocytes and neutrophils. We show here that short-term stimulation of primary human monocytes with LPS led to an i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6507f7951c55fbc1564d703c7c1a17dc
https://archive-ouverte.unige.ch/unige:768
https://archive-ouverte.unige.ch/unige:768
Despite the presence of tumor-specific effector cells in the circulation of cancer patients, the immune response of the majority of these patients is not sufficient to prevent the growth and spread of their tumors. That tumor cells can be killed in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba227998c7f60e680703be582da47b91
Publikováno v:
Vascular Pharmacology, Vol. 39, No 4-5 (2002) pp. 239-246
The function of endothelium is the lining of the vessel wall and the control of vascular permeability, homeostasis and leukocyte emigration from the blood into the surrounding tissue. Different adhesion molecules expressed in a coordinated and regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::903e7900686851c464ddd315a641003e
https://pubmed.ncbi.nlm.nih.gov/12747963
https://pubmed.ncbi.nlm.nih.gov/12747963
Autor:
Beat A. Imhof, Caroline Johnson-Leger, Michel Aurrand-Lions, Nicolas Fasel, Nicola Beltraminelli
Publikováno v:
Blood, Vol. 100, No 7 (2002) pp. 2479-2486
The molecular mechanisms underlying lymphocyte extravasation remain poorly characterized. We have recently identified junctional adhesion molecule-2 (JAM-2), and have shown that antibodies to JAM-2 stain high endothelial venules (HEVs) within lymph n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38fab9c3513fe0ccf6bbd81fef044b88
https://pubmed.ncbi.nlm.nih.gov/12239159
https://pubmed.ncbi.nlm.nih.gov/12239159