Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Caroline Joannesse"'
Autor:
Dominique Lambin, Katja Conrath, Tom De Munck, Ann De Blieck, Hans Kelgtermans, Steven Emiel Van Der Plas, Marlon D. Cowart, Christel Jeanne Marie Menet, Sebastien Dropsit, Caroline Joannesse, Oscar Mammoliti, Sebastien Laurent Xavier Martina, Maarten Gees, Giovanni Tricarico, Martin James Inglis Andrews, Anne-Sophie Wesse
Publikováno v:
Journal of Medicinal Chemistry. 64:343-353
Cystic fibrosis (CF) is a life-threatening recessive genetic disease caused by mutations in the gene encoding for the cystic fibrosis transmembrane conductance regulator (CFTR). With the discovery of Ivacaftor and Lumacaftor, it has been shown that a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95c3164798d3ba2edd8da65585ae94bc
https://doi.org/10.1021/acs.jmedchem.0c01796
https://doi.org/10.1021/acs.jmedchem.0c01796
Autor:
Thierry Christophe, Nicolas Houvenaghel, Philippe Clément-Lacroix, Reginald Brys, Line Oste, Inge Duys, Emanuelle Wakselman, Bertrand Heckmann, Caroline Joannesse, Alex Jaunet, Adeline Marie Elise Palisse, Brigitte Allart, Laurent Saniere, Mia Jans, Monica Borgonovi, Sandy El Bkassiny, Oscar Mammoliti, Beatrice Coornaert, Christel Jeanne Marie Menet, Kathleen Sonck
Publikováno v:
Journal of medicinal chemistry. 64(9)
Mounting evidence from the literature suggests that blocking S1P2 receptor (S1PR2) signaling could be effective for the treatment of idiopathic pulmonary fibrosis (IPF). However, only a few antagonists have been so far disclosed. A chemical enablemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8bf77a662664d4953efc380b9590624
https://pubmed.ncbi.nlm.nih.gov/33939425
https://pubmed.ncbi.nlm.nih.gov/33939425
Autor:
Sebastien Dropsit, Pieter F. W. Stouten, Linda Tomaskovic, Thierry Christophe, Ellen van der Aar, Maarten Gees, Luc Nelles, Mia Jans, Monica Borgonovi, Evelyne M. Quinton, Katja Conrath, Jan Van Der Schueren, Caroline Joannesse, Hans Kelgtermans, Martin James Inglis Andrews, Sebastien Laurent Xavier Martina, Oscar Mammoliti, Ann De Blieck, Steven Emiel Van Der Plas, Tom De Munck
Publikováno v:
Journal of Medicinal Chemistry. 61:1425-1435
Cystic fibrosis (CF) is caused by mutations in the gene for the cystic fibrosis transmembrane conductance regulator (CFTR). With the discovery of Ivacaftor and Orkambi, it has been shown that CFTR function can be partially restored by administering o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc1598dc3e22fb401aa0908c21814b75
https://doi.org/10.1021/acs.jmedchem.7b01288
https://doi.org/10.1021/acs.jmedchem.7b01288
Autor:
Steven Emiel Van Der Plas, Ann De Blieck, Dominique Lambin, Giovanni Tricarico, Martin James Inglis Andrews, Anne-Sophie Wesse, Marlon D. Cowart, Katja Conrath, Tom De Munck, Maarten Gees, Christel Jeanne Marie Menet, Hans Kelgtermans, Oscar Mammoliti, Caroline Joannesse, Sebastien Laurent Xavier Martina, Sebastien Dropsit
Publikováno v:
Journal of Medicinal Chemistry. 64:13933-13933
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef530fe540a7f240ca9942862582716b
https://doi.org/10.1021/acs.jmedchem.1c01537
https://doi.org/10.1021/acs.jmedchem.1c01537
Autor:
Steven E, Van der Plas, Hans, Kelgtermans, Tom, De Munck, Sébastien L X, Martina, Sébastien, Dropsit, Evelyne, Quinton, Ann, De Blieck, Caroline, Joannesse, Linda, Tomaskovic, Mia, Jans, Thierry, Christophe, Ellen, van der Aar, Monica, Borgonovi, Luc, Nelles, Maarten, Gees, Pieter, Stouten, Jan, Van Der Schueren, Oscar, Mammoliti, Katja, Conrath, Martin, Andrews
Publikováno v:
Journal of medicinal chemistry. 61(4)
Cystic fibrosis (CF) is caused by mutations in the gene for the cystic fibrosis transmembrane conductance regulator (CFTR). With the discovery of Ivacaftor and Orkambi, it has been shown that CFTR function can be partially restored by administering o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::528097bcdc809fb179a6c30494225cb7
https://pubmed.ncbi.nlm.nih.gov/29148763
https://pubmed.ncbi.nlm.nih.gov/29148763
Autor:
Andrew D. Smith, Craig D. Campbell, Louis C. Morrill, Caroline Joannesse, Alexandra M. Z. Slawin
Publikováno v:
Synthesis. 2011:1865-1879
The ability of a chiral isothiourea to promote the regio-and enantioselective O- to C-carboxyl transfer of a series of 3-alkyl-5-aryl- and 5-methyl-3-phenylfuranyl carbonates is examined, generating preferentially the α-regioisomers (α/γ up to 83:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ae48e35e7f7ed2836e59d27b4f7486b
https://doi.org/10.1055/s-0030-1260602
https://doi.org/10.1055/s-0030-1260602
Autor:
Craig D. Campbell, Carmen Concellon, Dorine Belmessieri, Nicolas Duguet, Andrew D. Smith, Philip A. Woods, Ryan A. Bragg, Caroline Joannesse, Callum I. MacGregor, Craig P. Johnston, Caroline Jones
Publikováno v:
Org. Biomol. Chem.. 9:559-570
The catalytic activity and enantioselectivity in the kinetic resolution of (±)-1-naphthylethanol with a range of structurally related 3,4-dihydropyrimido[2,1-b]benzothiazole-based catalysts is examined. Of the isothiourea catalysts screened, (2S,3R)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acd2b692d324c4920b64a212c997ea71
https://doi.org/10.1039/c0ob00515k
https://doi.org/10.1039/c0ob00515k
Autor:
Carmen Concellon, Andrew D. Smith, Craig P. Johnston, Carmen Simal, Douglas Philp, Caroline Joannesse
Publikováno v:
Angewandte Chemie International Edition. 48:8914-8918
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c94d926ecd588e444bbcf90631d8c76
https://doi.org/10.1002/anie.200904333
https://doi.org/10.1002/anie.200904333
Autor:
Andrew J. Miller, Carmen Concellon, Louis C. Morrill, Alexandra M. Z. Slawin, Philip Lenden, Jennifer E. Thomson, Caroline Joannesse, Katherine A. Gallagher, Andrew D. Smith, Andrew F. Kyle
Publikováno v:
Synthesis. 2008:2805-2818
The ability of N-heterocyclic carbenes to promote 0-to-C carboxyl transfer on a range of indolyl and benzofuranyl carbonates is examined, and the scope and limitations of this process delineated.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1683b18c493e6921b8db5cc119d37d5b
https://doi.org/10.1055/s-2008-1077890
https://doi.org/10.1055/s-2008-1077890
The authors would like to thank the Royal Society for a University Research Fellowship (ADS), The Carnegie Trust for the Universities of Scotland (CDC and LCM) and the EPSRC (CJ) for funding, and the EPSRC National Mass Spectrometry Service Centre (S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0d90c6e7cfb916ac9613210547c1783
https://hdl.handle.net/10023/6733
https://hdl.handle.net/10023/6733
