Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Caroline Jegerschöld"'
Autor:
Gefei Chen, Axel Leppert, Helen Poska, Harriet E. Nilsson, Carlos Piedrafita Alvira, Xueying Zhong, Philip Koeck, Caroline Jegerschöld, Axel Abelein, Hans Hebert, Jan Johansson
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-8 (2023)
Abstract ATP-independent molecular chaperones are important for maintaining cellular fitness but the molecular determinants for preventing aggregation of partly unfolded protein substrates remain unclear, particularly regarding assembly state and bas
Externí odkaz:
https://doaj.org/article/71ccbc7cbdc84d0cba35d704c18e4cb9
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0228607 (2020)
Among the first steps in inflammation is the conversion of arachidonic acid (AA) stored in the cell membranes into leukotrienes. This occurs mainly in leukocytes and depends on the interaction of two proteins: 5-lipoxygenase (5LO), stored away from t
Externí odkaz:
https://doaj.org/article/729de061a73a4fb58f7621a68ae22da2
Autor:
Tonje Bjørnetrø, Kathrine Røe Redalen, Sebastian Meltzer, Nirujah Sivarajah Thusyanthan, Rampradeep Samiappan, Caroline Jegerschöld, Karianne Risberg Handeland, Anne Hansen Ree
Publikováno v:
Journal of Extracellular Vesicles, Vol 8, Iss 1 (2019)
Tumour hypoxia contributes to poor treatment outcome in locally advanced rectal cancer (LARC) and circulating extracellular vesicles (EVs) as potential biomarkers of tumour hypoxia and adverse prognosis have not been fully explored. We examined EV mi
Externí odkaz:
https://doaj.org/article/6a2632bc067847c2b14b10deef94dfcd
Autor:
Qie Kuang, Pasi Purhonen, Johan Ålander, Richard Svensson, Veronika Hoogland, Jens Winerdal, Linda Spahiu, Astrid Ottosson-Wadlund, Caroline Jegerschöld, Ralf Morgenstern, Hans Hebert
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Microsomal glutathione transferase 1 (MGST1) is a detoxification enzyme belonging to the Membrane Associated Proteins in Eicosanoid and Glutathione Metabolism (MAPEG) superfamily. Here we have used electron crystallography of two-dimensional
Externí odkaz:
https://doaj.org/article/fe2feb0db1a94044957a8d5cb9db2cb5
Autor:
Jakob Toudahl Nielsen, Natalia V. Kulminskaya, Morten Bjerring, Juha M. Linnanto, Margus Rätsep, Marie Østergaard Pedersen, Petar H. Lambrev, Márta Dorogi, Győző Garab, Karen Thomsen, Caroline Jegerschöld, Niels-Ulrik Frigaard, Martin Lindahl, Niels Chr. Nielsen
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
The chlorosome of the photosynthetic bacterium C. tepidumharvests light and transfers the energy to the photosynthetic reaction centre. Here the authors determine the structure of the baseplate, a scaffolding super-structure, to show that the basepla
Externí odkaz:
https://doaj.org/article/11b81cc89417464ab8b2b9a3f42d0f15
Autor:
Ramakrishnan B Kumar, Lin Zhu, Helena Idborg, Olof Rådmark, Per-Johan Jakobsson, Agnes Rinaldo-Matthis, Hans Hebert, Caroline Jegerschöld
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152116 (2016)
An important step in the production of inflammatory mediators of the leukotriene family is the Ca2+ mediated recruitment of 5 Lipoxygenase (5LO) to nuclear membranes. To study this reaction in vitro, the natural membrane mimicking environment of nano
Externí odkaz:
https://doaj.org/article/755a0776bee44b2f8363b8b7efc427c3
Autor:
Christian Löw, Yin Hoe Yau, Els Pardon, Caroline Jegerschöld, Lisa Wåhlin, Esben M Quistgaard, Per Moberg, Susana Geifman-Shochat, Jan Steyaert, Pär Nordlund
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77984 (2013)
Mechanosensitive channels (MS) are integral membrane proteins and allow bacteria to survive sudden changes in external osmolarity due to transient opening of their pores. The efflux of cytoplasmic osmolytes reduces the membrane tension and prevents m
Externí odkaz:
https://doaj.org/article/3947c407b3fb436d8b9c27b3747ab996
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38244 (2012)
Progress in functional and structural studies of integral membrane proteins (IMPs) is lacking behind their soluble counterparts due to the great challenge in producing stable and homogeneous IMPs. Low natural abundance, toxicity when over-expressed a
Externí odkaz:
https://doaj.org/article/36a3d428bd464a8ca44d69aa969aca32
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 7, p e0228607 (2020)
PLoS ONE, Vol 15, Iss 7, p e0228607 (2020)
Among the first steps in inflammation is the conversion of arachidonic acid (AA) stored in the cell membranes into leukotrienes. This occurs mainly in leukocytes and depends on the interaction of two proteins: 5-lipoxygenase (5LO), stored away from t
Autor:
Peter Gysbers, Jitka Petrlova, Hans Hebert, Caroline Jegerschöld, Stefan Wallin, Lin Zhu, Jens O. Lagerstedt
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1861:2726-2738
Background Apolipoprotein A-I (apoA-I) in high-density lipoprotein (HDL) is a key protein for the transport of cholesterol from the vascular wall to the liver. The formation and structure of nascent HDL, composed of apoA-I and phospholipids, is criti