Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Caroline J, Coats"'
Autor:
Caroline J. Coats, Ahmad Masri, Michael E. Nassif, Roberto Barriales‐Villa, Michael Arad, Nuno Cardim, Lubna Choudhury, Brian Claggett, Hans‐Dirk Düngen, Pablo Garcia‐Pavia, Albert A. Hagège, James L. Januzzi, Matthew M. Y. Lee, Gregory D. Lewis, Chang‐Sheng Ma, Martin S. Maron, Zi Michael Miao, Michelle Michels, Iacopo Olivotto, Artur Oreziak, Anjali T. Owens, John A. Spertus, Scott D. Solomon, Jacob Tfelt‐Hansen, Marion van Sinttruije, Josef Veselka, Hugh Watkins, Daniel L. Jacoby, Polina German, Stephen B. Heitner, Stuart Kupfer, Justin D. Lutz, Fady I. Malik, Lisa Meng, Amy Wohltman, Theodore P. Abraham
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 15 (2024)
Background Aficamten, a novel cardiac myosin inhibitor, reversibly reduces cardiac hypercontractility in obstructive hypertrophic cardiomyopathy. We present a prespecified analysis of the pharmacokinetics, pharmacodynamics, and safety of aficamten in
Externí odkaz:
https://doaj.org/article/ecd7f5b3949f4a8ca276c42cd7292a3f
Autor:
Wendy E. Heywood, Jon Searle, Richard Collis, Ivan Doykov, Michael Ashworth, Neil Sebire, Andrew Bamber, Mathias Gautel, Simon Eaton, Caroline J. Coats, Perry M. Elliott, Kevin Mills
Publikováno v:
Life, Vol 14, Iss 8, p 970 (2024)
Proteomics studies often explore phenotypic differences between whole organs and systems. Within the heart, more subtle variation exists. To date, differences in the underlying proteome are only described between whole cardiac chambers. This study, u
Externí odkaz:
https://doaj.org/article/c8a6dfe6be694246b433b3a2ecda8baf
Autor:
William E. Moody, Lauren Turvey-Haigh, Daniel Knight, Caroline J. Coats, Robert M. Cooper, Rebecca Schofield, Shaun Robinson, Allan Harkness, David L. Oxborough, Julian D. Gillmore, Carol Whelan, Daniel X. Augustine, Marianna Fontana, Richard P. Steeds
Publikováno v:
Echo Research and Practice, Vol 10, Iss 1, Pp 1-25 (2023)
Abstract These guidelines form an update of the BSE guideline protocol for the assessment of restrictive cardiomyopathy (Knight et al. in Echo Res Prac, 2013). Since the original recommendations were conceived in 2013, there has been an exponential r
Externí odkaz:
https://doaj.org/article/8b6cdb6721e34b0fbf54ec05925e496e
Publikováno v:
Cardiogenetics, Vol 6, Iss 1 (2016)
Troponins are thin myofilament proteins that regulate the contraction of cardiac and skeletal muscle. The cardio-specific troponin I (TnI) and T (TnT) proteins are sensitive and specific biomarkers of myocardial injury which over the past twenty year
Externí odkaz:
https://doaj.org/article/7b2376cf6d174071b6a918ebfcdb2f27
Autor:
Julian D, Gillmore, Mary M, Reilly, Caroline J, Coats, Rob, Cooper, Helen, Cox, Mark R E, Coyne, Andrew J, Green, Ruth, McGowan, William E, Moody, Philip N, Hawkins
Publikováno v:
Advances in therapy. 39(6)
Hereditary transthyretin-mediated amyloidosis (hATTR) is challenging to diagnose early owing to the heterogeneity of clinical presentation, which differs according to the TTR gene variant and its penetrance in each individual. The TTR variants seen m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d5f4431cb181c2982fef46f5ca918880
https://pubmed.ncbi.nlm.nih.gov/35419651
https://pubmed.ncbi.nlm.nih.gov/35419651
Autor:
Marilou Huang, Omar Aldalati, Niall G Campbell, Andrew Kennedy, T Irvine, Vetton Chee Kay Lee, Jamal Nasir Khan, Emily Robins, Christopher Eggett, Haotian Gu, Sonecki Piotr, Simon Duckett, Petros Nihoyannopoulos, Keith Pearce, Martin Stout, Sinead Cabezon, Peter Luke, Stavros Apostolakis, Anna Barton, Mehdi Eskandari, David Slessor, Tamara Naneishvili, Thomas Jake Turner, Shaun Robinson, Vishal Sharma, Prathap Kanagala, Arron Pasricha, Liam Batchelor, Bernard Prendergast, Paul Woodmansey, Theodoros Ntoskas, Andreea Mihai, Sean Coffey, Caroline Bleakley, Richard Crawley, Brogan McAdam, Linda Arnold, Hwee Phen Teh, Tamseel Fatima, Allan L. Klein, Anita Macnab, Chih Wong, Loakim Spyridopoulos, Nicolas E R Goodfield, Jo Wilson, Saul G. Myerson, Alan C. Cameron, Caroline J Coats, Phang Gyee Vuei, Andrew J Fletcher, Bushra S. Rana, Matthew M.Y. Lee, Grant Heatlie, Shanat Baig, Conor Steele, Timothy Griffiths, Almira R Whittaker, Farhanda Ahmad, Maryam Alsharqi, Emma Lane, Vera Lennie, Phil Chowienczyk, Christos Voukalis, Chun Shing Kwok, Mark J. Monaghan, Louise C Mayall, Kully Sandhu, Alice M Jackson, Nashwah Ismail, Robert Butler, Margaret Loudon, Hannah Garnett
Publikováno v:
Echo Research & Practice. 6:M1-M2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4f5e2812b8386f51d5da9344e0ec20d
https://doi.org/10.1530/erp-19-0056
https://doi.org/10.1530/erp-19-0056
Autor:
Caroline J. Coats, Wendy E. Heywood, Alex Virasami, Nadia Ashrafi, Petros Syrris, Cris dos Remedios, Thomas A. Treibel, James C. Moon, Luis R. Lopes, Christopher G.A. McGregor, Michael Ashworth, Neil J. Sebire, William J. McKenna, Kevin Mills, Perry M. Elliott
Publikováno v:
Circulation: Genomic and Precision Medicine. 11
Background: Hypertrophic cardiomyopathy (HCM) is characterized by a complex phenotype that is only partly explained by the biological effects of individual genetic variants. The aim of this study was to use proteomic analysis of myocardial tissue to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7411569404626ea1f621023a6bd2f418
https://doi.org/10.1161/circgenetics.117.001974
https://doi.org/10.1161/circgenetics.117.001974
Autor:
Caroline J. Coats
Publikováno v:
International journal of cardiology. 271
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fabe80b3ae305909876c9294faf7b5f
https://pubmed.ncbi.nlm.nih.gov/30087038
https://pubmed.ncbi.nlm.nih.gov/30087038
Autor:
Jonathan R. Dalzell, Pardeep S. Jhund, Niki Walker, Caroline J Coats, Mark C. Petrie, Alice M Jackson
Learning objectives In 2010, the Heart Failure Association of the European Society of Cardiology Working Group on peripartum cardiomyopathy (PPCM) defined PPCM as ‘an idiopathic cardiomyopathy presenting with heart failure secondary to left ventric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88b2fca048382be36d128129358b35f7
https://eprints.gla.ac.uk/148487/7/148487.pdf
https://eprints.gla.ac.uk/148487/7/148487.pdf
Autor:
Francesco Papalia, Simon Woldman, Michael A. Kuskowski, Inder S. Anand, Adrian S. H. Cheng, Hua Zen Ling, Swan Kang, Morten Damgaard, Suneil Aggarwal, Shanti Velmurugan, Julia Flint, Susanne Weissert, Mohammed Rashid, Michelle Mendonca, Martin Thomas, Peter K. Bonfils, Jay N. Cohn, Caroline J. Coats, Darlington O. Okonko
Publikováno v:
European Journal of Heart Failure. 17:35-43
© 2014 The Authors European Journal of Heart Failure © 2014 European Society of Cardiology. Aims: Plasma volume (PV) expansion hallmarks worsening chronic heart failure (CHF) but no non-invasive means of quantifying volume status exists. Because we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1da2095a87a7db361d950d6c308cccd
https://doi.org/10.1002/ejhf.193
https://doi.org/10.1002/ejhf.193