Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Caroline I. Biggs"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Controlling the formation and growth of ice is essential to successfully cryopreserve cells, tissues and biologics. Current efforts to identify materials capable of modulating ice growth are guided by iterative changes and human intuition, w
Externí odkaz:
https://doaj.org/article/65f0ec4221bf437b8ae453f8701362a3
Autor:
Caroline I. Biggs, Trisha L. Bailey, Ben Graham, Christopher Stubbs, Alice Fayter, Matthew I. Gibson
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Ice crystal growth is a major problem in cell and tissue cryopreservation for transplantation, transfusion, icing of aircraft wings and many other applications. Here the authors review the emerging field of synthetic macromolecular mimics of antifree
Externí odkaz:
https://doaj.org/article/8caf30d010064db999f55b38abc30c34
Autor:
Alexander James Zwetsloot, Panagiotis G. Georgiou, Ashfaq Ahmad, Neil R Anderson, Caroline I. Biggs, Sarojini Pandey, Alexander N. Baker, Dimitris K. Grammatopoulos, Muhammad Hasan, Simone Dedola, Marc Walker, Robert A. Field, Matthew I. Gibson, Anne Straube, Sarah-Jane Richards, Collette S. Guy
Publikováno v:
ACS Sensors
The COVID-19 pandemic, and future pandemics, require diagnostic tools to track disease spread and guide the isolation of (a)symptomatic individuals. Lateral-flow diagnostics (LFDs) are rapid and of lower cost than molecular (genetic) tests, with curr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38f35a0c593196b289cc5ea558caa897
http://europepmc.org/articles/PMC8525701
http://europepmc.org/articles/PMC8525701
Autor:
Maria Michela Corsaro, Rosa Lanzetta, Matthew I. Gibson, Marie-Sousai Appavou, Angela Casillo, Luigi Paduano, Maria Luisa Tutino, Ermenegilda Parrilli, Aurel Radulescu, Antonio Fabozzi, Irene Russo Krauss, Caroline I. Biggs
Publikováno v:
Biomacromolecules 22, 1445-1457 (2021). doi:10.1021/acs.biomac.0c01659
Biomacromolecules
Biomacromolecules
Extracellular polysaccharides are widely produced by bacteria, yeasts, and algae. These polymers are involved in several biological functions, such as bacteria adhesion to surface and biofilm formation, ion sequestering, protection from desiccation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df21bcb556a89e2d1a699f19678142a7
http://wrap.warwick.ac.uk/150494/7/WRAP-physicochemical-approach-understanding-structure-conformation-activity-mannan-polysaccharides-Gibson-2021.pdf
http://wrap.warwick.ac.uk/150494/7/WRAP-physicochemical-approach-understanding-structure-conformation-activity-mannan-polysaccharides-Gibson-2021.pdf
Publikováno v:
Biomacromolecules
Surface-grafted polymers have been widely applied to modulate biological interfaces and introduce additional functionality. Polymers derived from reversible addition–fragmentation transfer (RAFT) polymerization have a masked thiol at the ω-chain e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::596d5fff39bd7687f7d87039927dced9
https://doi.org/10.1021/acs.biomac.6b00662
https://doi.org/10.1021/acs.biomac.6b00662
Autor:
Caroline I. Biggs, Matthew I. Gibson, Christopher Packer, Steven A. Hindmarsh, Neil R. Wilson, Jonathan P. Rourke, Marc Walker
Publikováno v:
Physical Chemistry Chemical Physics
Base-washed graphene-oxide which has been sequentially modified by thiol-epoxy chemistry, results in materials with ice nucleation activity. The role of hydro-philic/phobic grafts and polymers was evaluated with the most potent functioning at just 0.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad12d2c3046e708c5d73c3c8e7f741b7
http://wrap.warwick.ac.uk/91013/13/WRAP-impact-of-sequential-surface-modification-Biggs--2017.pdf
http://wrap.warwick.ac.uk/91013/13/WRAP-impact-of-sequential-surface-modification-Biggs--2017.pdf
Publikováno v:
ACS Macro Letters
Polymer mimics of antifreeze proteins are emerging as an exciting class of macromolecular cryoprotectants for the storage of donor cells and tissue. Poly(vinyl alcohol), PVA, is the most potent polymeric ice growth inhibitor known, but its mode of ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0107296a50042f03db60c0a33ffc1a1
https://europepmc.org/articles/PMC5718289/
https://europepmc.org/articles/PMC5718289/
Autor:
Ben Graham, Matthew I. Gibson, Christopher D. Stubbs, Trisha L. Bailey, Caroline I. Biggs, Alice E. R. Fayter
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Antifreeze proteins from polar fish species are remarkable biomacromolecules which prevent the growth of ice crystals. Ice crystal growth is a major problem in cell/tissue cryopreservation for transplantation, transfusion and basic biomedical researc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fdaa106de74069d2760ea697d3b936f
https://pubmed.ncbi.nlm.nih.gov/29142216
https://pubmed.ncbi.nlm.nih.gov/29142216
Autor:
Luigi Paduano, Emiliano Bedini, Sandro Cosconati, Alfonso Iadonisi, Angela Casillo, Caroline I. Biggs, Antonio Laezza, Antonio Randazzo, Maria Michela Corsaro, Matthew I. Gibson, Ettore Novellino, Antonio Fabozzi
Publikováno v:
Biomacromolecules
Several threonine (Thr)- and alanine (Ala)-rich antifreeze glycoproteins (AFGPs) and polysaccharides act in nature as ice recrystallization inhibitors. Among them, the Thr-decorated capsular polysaccharide (CPS) from the cold-adapted Colwellia psychr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::013cfd0ed30315c049614590c2dd7eca
http://hdl.handle.net/11591/376613
http://hdl.handle.net/11591/376613
Autor:
Christopher D. Stubbs, Muhammad Hasan, Alice E. R. Fayter, Caroline I. Biggs, Ben Graham, Matthew I. Gibson
Publikováno v:
Macromolecular Bioscience
Macromolecular bioscience
Macromolecular bioscience
Antifreeze proteins and ice‐binding proteins have been discovered in a diverse range of extremophiles and have the ability to modulate the growth and formation of ice crystals. Considering the importance of cryoscience across transport, biomedicine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bbff76a164628880fecce94da22a776
https://doi.org/10.1002/mabi.201900082
https://doi.org/10.1002/mabi.201900082